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The Efficacy of Low-Level Continuous Positive Airway Pressure for the Treatment of Snoring
Open accessAbstract
Study objectives To assess effects of low-level continuous positive airway pressure (CPAP) on snoring in habitual snorers without obstructive sleep apnea (OSA).Methods A multicenter prospective in-laboratory reversal crossover intervention trial was conducted between September 2013 and August 2014. Habitual snorers were included if they snored (inspiratory sound pressure level ≥ 40 dBA) for ≥ 30% all sleep breaths on a baseline sleep study (Night 1), and if significant OSA and daytime somnolence were absent. Included participants then underwent a CPAP titration study at 2, 4, or 6 cm H 2 O (Night 2) to examine snoring responses to step-increases in nasal pressure, a treatment night at optimal pressure (Night 3), followed by baseline night (Night 4). At each pressure, snoring intensity was measured on each breath. Snoring frequency was quantified as a percentage of sleep breaths at thresholds of 40, 45, 50, and 55 dBA. Sleep architecture and OSA severity were characterized using standard measurements.Results On baseline sleep studies, participants demonstrated snoring at ≥ 40 dBA on 53 ± 3% and ≥ 45 dBA on 35 ± 4% of breaths. Snoring frequency decreased progressively as nasal pressure increased from 0 to 4 cm H 2 O at each threshold, and plateaued thereafter. CPAP decreased snoring frequency by 67% and 85% at 40 and 45 dBA, respectively. Intervention did not alter sleep architecture and sleep apnea decreased minimally.Conclusions Low-level CPAP below the range required to treat OSA diminished nocturnal snoring, and produced uniform reduction in nightly noise production below the World Health Organization's limit of 45 dBA.Clinical trial registration ClinicalTrials.gov, identifier: NCT01949584.
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Role of Nasal Surgery in Adult Obstructive Sleep Apnea: A Systematic Review
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Metadata
- Authors
- Guzman, M. A., Sgambati, F. P., Pho, H., Arias, R. S., Hawks, E. M., Wolfe, E. M., Ötvös, T., Rosenberg, R., Dakheel, R., Schneider, H., Kirkness, J. P., Smith, P. L., & Schwartz, A. R.
- Affiliations
- Johns Hopkins University (US)
- NeuroTrials Research (United States) (US)
- Doctors Community Hospital (US)
- ORCID
- Venue
- Journal of Clinical Sleep Medicine
- Published
- 2017-05-15
- Volume
- 13
- Issue
- 5
- Pages
- 703-711
- ISSN
- 1550-9389 (ISSN-L)
- 1550-9397
- PMC
- PMC5406953
- OpenAlex
- W2613447757
- Cited by
- 12
- References
- 48
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 2 · 2020: 5 · 2019: 1
- FWCI
- 1.21
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Clinical Sleep Medicine (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Keywords
- snoring, continuous positive airway pressure, obstructive sleep apnea, snoring frequency, nasal pressure, sleep architecture, snoring intensity
- MeSH terms
- Female, Humans, Male, Middle Aged, Prospective Studies, Snoring, Treatment Outcome, Cross-Over Studies, Continuous Positive Airway Pressure
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