Cited by 40Obstructive Sleep Apnea ResearchNon-Invasive Vital Sign MonitoringSleep and related disorders

Screening of obstructive sleep apnea in patients who snore using a patch-type device with electrocardiogram and 3-axis accelerometer

Open access
Hsu, Ying-Shuo, Chen, Tien-Yu, Wu, Dean, Lin, Chia-Mo, Juang, Jer-Nan, Liu, Wen-Te·2020·Journal of Clinical Sleep Medicine

Abstract

Study objectives People with obstructive sleep apnea (OSA) remain undiagnosed because of the lack of easy and comfortable screening tools. Through this study, we aimed to compare the diagnostic accuracy of chest wall motion and cyclic variation of heart rate (CVHR) in detecting OSA by using a single-lead electrocardiogram (ECG) patch with a 3-axis accelerometer.Methods In total, 119 patients who snore simultaneously underwent polysomnography with a single-lead ECG patch. Signals of chest wall motion and CVHR from the single-lead ECG patch were collected. The chest effort index (CEI) was calculated using the chest wall motion recorded by a 3-axis accelerometer in the device. The ability of CEI and CVHR indices in diagnosing moderate-to-severe OSA (apnea-hypopnea index ≥ 15) was compared using the area under the curve (AUC) by using the DeLong test.Results CVHR detected moderate-to-severe OSA with 52.9% sensitivity and 94.1% specificity (AUC: 0.76, 95% confidence interval: 0.67-0.84, optimal cutoff: 21.2 events/h). By contrast, CEI identified moderate-to-severe OSA with 80% sensitivity and 79.4% specificity (AUC: 0.87, 95% confidence interval: 0.80-0.94, optimal cutoff: 7.1 events/h). CEI significantly outperformed CVHR regarding the discrimination ability for moderate-to-severe OSA (ΔAUC: 0.11, 95% confidence interval: 0.009-0.21, P = .032). For determining severe OSA, the performance of discrimination ability was greater (AUC = 0.90, 95% confidence interval: 0.85-0.95) when combining these two signals.Conclusions Both CEI and CVHR recorded from a patch-type device with ECG and a 3-axis accelerometer can be used to detect moderate-to-severe OSA. Thus, incorporation of CEI is helpful in the detection of sleep apnea by using a single-lead ECG with a 3-axis accelerometer.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.5664/jcsm.8462

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The e-tattoo achieves one of the lowest current draws (940 μA) among wearable cardiac sensors developed in prior work.

    “This form factor coupled with innovative firmware for sensor interfacing and transmission of data allows us to achieve one of the lowest total device weights (2.5 g including battery) and current draws (940 µ A) among wearable cardiac sensors developed in prior work as illustrated via Ashby plot in Figure 1e. [18-24]”
  • The e-tattoo achieves one of the lowest total device weights (2.5 g including battery) among wearable cardiac sensors developed in prior work.

    “This form factor coupled with innovative firmware for sensor interfacing and transmission of data allows us to achieve one of the lowest total device weights (2.5 g including battery) and current draws (940 µ A) among wearable cardiac sensors developed in prior work as illustrated via Ashby plot in Figure 1e. [18-24]”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Hsu, Y.-S., Chen, T.-Y., Wu, D., Lin, C.-M., Juang, J.-N., & Liu, W.-T.
Affiliations
  • Fu Jen Catholic University (TW)
  • Tri-Service General Hospital (TW)
  • Taipei Medical University-Shuang Ho Hospital (TW)
  • National Cheng Kung University (TW)
  • Taipei Medical University Hospital (TW)
Corresponding author
Liu, Wen-Te
Venue
Journal of Clinical Sleep Medicine
Published
2020-07-15
Volume
16
Issue
7
Pages
1149-1160
ISSN
  • 1550-9389 (ISSN-L)
  • 1550-9397
OpenAlex
W3015147832
Cited by
40
References
37
Citations by year
2026: 7 · 2025: 4 · 2024: 7 · 2023: 9 · 2022: 3 · 2021: 9 · 2020: 1
FWCI
3.30
Type
journal article
Language
en
Open access
Locations
  • Journal of Clinical Sleep Medicine (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
  • Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Keywords
obstructive sleep apnea, sleep apnea screening, snoring, chest wall motion, single-lead ECG, 3-axis accelerometer, wearable devices, diagnostic accuracy, apnea-hypopnea index
MeSH terms
Electrocardiography, Humans, Sleep Apnea Syndromes, Polysomnography, Sleep Apnea, Obstructive, Accelerometry

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review