The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
The Effect of Exercise Training on Obstructive Sleep Apnea and Sleep Quality: A Randomized Controlled Trial
Open accessAbstract
STUDY OBJECTIVES: To evaluate the efficacy of a 12-week exercise training program for reducing obstructive sleep apnea (OSA) severity and improving sleep quality, and to explore possible mechanisms by which exercise may reduce OSA severity. DESIGN: Randomized controlled trial. SETTING: Clinical exercise physiology center, sleep laboratory. PARTICIPANTS: Forty-three sedentary and overweight/obese adults aged 18-55 years with at least moderate-severity untreated OSA (screening apnea-hypopnea index [AHI] ≥ 15). INTERVENTIONS: Participants randomized to exercise training (n = 27) met 4 times/week for 12 weeks and performed 150 min/week of moderate-intensity aerobic activity, followed by resistance training twice/week. Participants randomized to a stretching control (n = 16) met twice weekly for 12 weeks to perform low-intensity exercises designed to increase whole-body flexibility. MEASUREMENTS AND RESULTS: OSA severity was assessed with one night of laboratory polysomnography (PSG) before and following the 12-week intervention. Measures of sleep quality included PSG, actigraphy (7-10 days), and the Pittsburgh Sleep Quality Index. Compared with stretching, exercise resulted in a significant AHI reduction (exercise: 32.2 ± 5.6 to 24.6 ± 4.4, stretching: 24.4 ± 5.6 to 28.9 ± 6.4; P < 0.01) as well as significant changes in oxygen desaturation index (ODI; P = 0.03) and stage N3 sleep (P = 0.03). Reductions in AHI and ODI were achieved without a significant decrease in body weight. Improvements in actigraphic sleep and subjective sleep quality were also noted following exercise compared with stretching. CONCLUSIONS: Exercise training had moderate treatment efficacy for the reduction of AHI in sedentary overweight/obese adults, which suggests that exercise may be beneficial for the management of OSA beyond simply facilitating weight loss. TRIAL REGISTRATION: Clinicaltrials.gov identification number NCT00956423.
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Cites
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Self-citationSleep-disordered Breathing and Cardiovascular Disease
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Cited by
Diagnosis and Management of Obstructive Sleep Apnea: A Review
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Metadata
- Authors
- Kline, C. E., Crowley, E. P., Ewing, G. B., Burch, J. B., Blair, S. N., Durstine, J. L., Davis, J. M., & Youngstedt, S. D.
- Venue
- Sleep
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-12
- Volume
- 34
- Issue
- 12
- Pages
- 1631-1640
- ISSN
- 0161-8105 (ISSN-L)
- 1550-9109
- OpenAlex
- W1974402435
- Cited by
- 354
- References
- 11
- FWCI
- 12.52
- Type
- journal article
- Language
- en
- Open access
- bronze
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