Caffeine-induced cardiac arrhythmia: an unrecognised danger of healthfood products
Abstract
We describe a 25-year-old woman with pre-existing mitral valve prolapse who developed intractable ventricular fibrillation after consuming a "natural energy" guarana health drink containing a high concentration of caffeine. This case highlights the need for adequate labelling and regulation of such products.
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Acute intake of caffeine stimulates a modest increase in blood pressure (both systolic and diastolic), effects on heart rate (bradycardia or tachycardia, depending on dose), and neuroendocrine effects (release of epinephrine, norepinephrine, and renin).
“In general, acute intake of caffeine stimulates a modest increase in blood pressure (both systolic and diastolic), effects on heart rate (bradycardia or tachycardia, depending on dose), and neuroendocrine effects (release of epinephrine, norepinephrine, and renin) (101).”
From The Safety of Ingested Caffeine: A Comprehensive Review (2017) · cites this paper as [101]
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- Authors
- Cannon, M. E., Cooke, C. T., & McCarthy, J. S.
- Affiliations
- Fremantle Hospital (AU)
- Queen Elizabeth II Medical Centre (AU)
- The University of Western Australia (AU)
- ORCID
- McCarthy, James S
- Venue
- Medical Journal of Australia
- Publisher
- AMPCo
- Published
- 2001-05
- Volume
- 174
- Issue
- 10
- Pages
- 520-521
- ISSN
- 0025-729X (ISSN-L)
- 1326-5377
- OpenAlex
- W56477952
- Cited by
- 136
- References
- 17
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 4 · 2023: 2 · 2022: 4 · 2021: 6 · 2020: 6 · 2019: 4 · 2018: 7 · 2017: 13 · 2016: 4 · 2015: 7 · 2014: 7 · 2013: 10 · 2012: 15
- FWCI
- 1.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- The Medical Journal of Australia (publishedVersion)
- PubMed (publishedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Coffee research and impacts
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Keywords
- caffeine, cardiac arrhythmias, ventricular fibrillation, guarana, health foods, functional beverages, mitral valve prolapse, product labeling, food regulation, adverse drug reactions
- MeSH terms
- Adult, Beverages, Caffeine, Drug Combinations, Female, Humans, Mitral Valve Prolapse, Theobromine, Theophylline, Ventricular Fibrillation, Fatal Outcome, Food, Organic
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