The role of different exercises in irisin, heat shock protein 70 and some biochemical parameters
Open accessAbstract
Background: The aim of the study was to determine the effects of different and regularly applied exercise programs on irisin, heat shock protein 70 and some biochemical parameters. Methods: 120 male university students participated in the study. Participants were divided into 4 equal groups as control (C), resistance exercise group (RE), high intensity interval (HIIT) and aerobic exercise group (AE). While the control group did not perform any exercise, the pre-determined exercise programs were applied to the other groups for 8 weeks and 3 days in a week. Blood samples were taken from all participants before and after the exercise program. Cholesterol, High-density Lipoprotein (HDL) and Low-density Lipoprotein (LDL) cholesterol, triglyceride (TG), Creatine kinase (CK), Lactate dehydrogenase (LDH), Irisin and Heat shock protein 70 (HSP70) levels were analyzed in blood samples. Results: It is determined that there are significant differences in pre-posttest values of the AE group's LDH, cholesterol, HDL-cholesterol, TG and HSP 70 levels, HIIT group's CK, LDH, Cholesterol, HDL-cholesterol, TG, Irisin and HSP70 levels and RE group's CK, LDH, Cholesterol, LDL-cholesterol, TG and Irisin levels (p<0.05). Conclusions: It can be said that exercise can provide improvements in lipid profile, changes in HSP70 levels may vary depending on muscle damage, the increase of irisin due to exercise.
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Endurance training increases circulating irisin in healthy adults.
“It has been reported that endurance training increases circulating irisin in healthy adults [41].”
From Exercise-Induced Myokines in Obesity-Related Metabolic Disorders and Cardiovascular Protection: A Narrative Review (2026) · cites this paper as [41]
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“It has been reported that endurance training increases circulating irisin in healthy adults [41].”
- Authors
- Akbulut, T., Cinar, V., Aydin, S., & Yardim, M.
- Affiliations
- Fırat University (TR)
- ORCID
- Akbulut, Taner
- Venue
- Journal of Medical Biochemistry
- Published
- 2022
- Volume
- 41
- Issue
- 2
- Pages
- 149-155
- ISSN
- 1452-8266 (ISSN-L)
- 1452-8258
- PMC
- PMC9010043
- OpenAlex
- W3194173387
- Cited by
- 14
- References
- 20
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 6 · 2023: 2 · 2022: 2
- FWCI
- 1.31
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Journal of Medical Biochemistry (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- DSpace - FIRAT (Fırat University) (submittedVersion, cc-by-nc-nd)
- Topics
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Keywords
- irisin, HSP70, resistance training, high-intensity interval training, aerobic exercise, exercise training, lipid profile, creatine kinase, lactate dehydrogenase, muscle damage, cholesterol, triglycerides, university students
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