Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling

Wilkinson, Dan C., Alva-Ornelas, Jackelyn A., Sucre, Jennifer M.S., Vijayaraj, Preethi, Durra, Abdo, Richardson, Wade, Jonas, Steven J., Paul, Manash K. +3 more·2017·Stem Cells Translational Medicine

Cited by (165)

Items 101–165 of 165

  1. A Novel Airway-Organoid Model Based on a Nano-Self-Assembling Peptide: Construction and Application in Adenovirus Infection Studies
    Yun-E Xu, Di-Shu Ao, Xin Sun, Wei Chen, Xue Luo, Can Zhao, Shengyu Wang, Hong Yan Song · 2023 · International Journal of Nanomedicine
  2. Current strategies and opportunities to manufacture cells for modeling human lungs
    Ratna Varma, John P. Soleas, Thomas K. Waddell, Golnaz Karoubi, Alison P. McGuigan · 2020 · Advanced Drug Delivery Reviews
  3. Induced Pluripotent Stem Cell-Derived Organoids: Their Implication in COVID-19 Modeling
    Mária Csöbönyeiová, Martin Klein, Marcela Kuniaková, Ivan Varga, Ľuboš Danišovič · 2023 · International Journal of Molecular Sciences
  4. Construction of artificial lung tissue structure with 3D-inkjet bioprinting core for pulmonary disease evaluation
    Weimin Wan, Xi Wang, Rongtao Zhang, Yixuan Li, Hang Wu, Yiman Liu, Fan Zhang, Jia Liu, Guiquan Liu, Lin Zhou et al. · 2025 · Journal of Tissue Engineering
  5. Advanced Non-animal Models in Biomedical Research: Respiratory Tract Diseases
    Hynes Jarlath, Marshall Lindsay, Ian Michael Adcock, Novotny Tomas, Miloslav Nič, Kryštof Dibusz, Laura Gribaldo, Whelan Maurice · 2020 · Joint Research Centre (European Commission)
  6. Modeling of Respiratory Diseases Evolving with Fibrosis from Organoids Derived from Human Pluripotent Stem Cells
    Irene Chamorro-Herrero, Alberto Zambrano · 2023 · International Journal of Molecular Sciences
  7. Proceedings: Regenerative Medicine for Lung Diseases: A CIRM Workshop Report
    Lisa C. Kadyk, Natalie D. DeWitt, Brigitte N. Gomperts · 2017 · Stem Cells Translational Medicine
  8. Lung-on-a-chip platforms for modeling disease pathogenesis
    Alessandra Dellaquila, Emma Thomée, Alexander H. McMillan, Sasha Cai Lesher‐Pérez · 2019 · Elsevier eBooks
  9. A Two-Dimensional Human Minilung System (Model) for Respiratory Syncytial Virus Infections
    Esmeralda Magro-López, Trinidad Guijarro, Isidoro Martínez, María Martin‐Vicente, Isabel Liste, Alberto Zambrano · 2017 · Viruses
  10. Organoid Technology and the COVID Pandemic
    Ria Sanyal, Manash Kumar Paul · 2021 · IntechOpen eBooks
  11. Leveraging mechanobiology and biophysical cues in lung organoids for studying lung development and disease
    Ziming Shao, Paolo De Coppi, Federica Michielin · 2023 · Frontiers in Chemical Engineering
  12. State of the Art in 3D Culture Models Applied to Thyroid Cancer
    Alessandro Prete, Antonio Matrone, Roberto Plebani · 2024 · Medicina
  13. Emerging Opportunities in Human Pluripotent Stem-Cells Based Assays to Explore the Diversity of Botulinum Neurotoxins as Future Therapeutics
    Juliette Duchesne de Lamotte, Anselme L. Perrier, Cécile Martinat, Camille Nicoleau · 2021 · International Journal of Molecular Sciences
  14. Reconstructing the lung stem cell niche in vitro
    Dayanand Swami, Jyotirmoi Aich, Bharti Bisht, Manash Kumar Paul · 2022 · Advances in stem cells and their niches
  15. Innovative approaches in lung tissue engineering: the role of exosome-loaded bioscaffolds in regenerative medicine
    Mohammad Torkashvand, Leila Rezakhani, Zahra Habibi, Abdolhamid Mikaeili, Shima Rahmati · 2024 · Frontiers in Bioengineering and Biotechnology
  16. Organoids and Commercialization
    Anubhab Mukherjee, Aprajita Sinha, Maheshree Maibam, Bharti Bisht, Manash Kumar Paul · 2022 · Biomedical engineering
  17. Upscaling: efficient generation of human lung organoids from induced pluripotent stem cells using a stirring bioreactor
    Bettina Budeus, Chiara Kroepel, Zehra Fatma Sevindik, Luca Fabian Buttler, Diana Klein · 2025 · Frontiers in Bioengineering and Biotechnology
  18. RGD-Alginate beads as scaffolds for culturing primary human dermal and pulmonary fibroblasts
    M.C. Stahl, K.G. Bergendahl, Daria Zaytseva‐Zotova, K.R. Rytterager, Catherine Taylor Nordgård, Joachim Sebastian Kjesbu, H. Haslene-Hox, Ø. Halaas, Pål Sætrom, AS Chahal et al. · 2026 · Carbohydrate Polymers
  19. Natural biopolymer-based hydrogels as designer matrices for organoid cultures
    Yun Kee Jo · 2023 · Organoid
  20. Lung tissue bioengineering for transplantation and modelling of development, disease and regeneration
    Martina M. De Santis, Federica Michielin, Soichi Shibuya, Paolo De Coppi, Darcy Elizabeth Wagner · 2021 · European Respiratory Society eBooks
  21. The Scar-in-a-Jar: In Vitro Fibrosis Model for Anti-Fibrotic Drug Testing
    Simon Stebler, Michael Raghunath · 2021 · Methods in molecular biology
  22. Bioreactors in Regenerative Medicine
    Jin-Ho Kim, Kelsey M. Kennedy, Gordana Vunjak‐Novakovic · 2018 · Elsevier eBooks
  23. From the pathophysiology of the human lung alveolus to epigenetic editing: Congress 2018 highlights from ERS Assembly 3 “Basic and Translational Science.”
    Marko Nikolić, Eva Maria Garrido-Martin, Flavia R. Greiffo, Aurélie Fabre, Irene H. Heijink, Agnes W. Boots, Catherine M. Greene, Pieter Sicco Hiemstra, Sabine Bartel · 2019 · ERJ Open Research
  24. Acute ascites with blunt cardiac rupture.
    François Dagenais, L Dion, Gilles Beauchamp · 1996 · PubMed
  25. Small cell lung cancer co-culture organoids provide insights into cancer cell survival after chemotherapy
    Chandani Sen, Caroline R. Koloff, Souvik Kundu, Dan Wilkinson, Juliette M. Yang, David W. Shia, Luisa K. Meneses, Tammy M. Rickabaugh, Brigitte N. Gomperts · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  26. TGF-β signaling in organoids: The mechanisms and applications in 3D
    Shichao Zhu, Jing Liu, Xuewen Qiu, Guoqing Cai, Mei Gao · 2025 · Cell organoid (Print)
  27. The Development of Lung Tissue Engineering: From Biomaterials to Multicellular Systems
    Jingge Ma, Chengtie Wu, Jin‐Fu Xu · 2024 · Advanced Healthcare Materials
  28. Rising influence of synthetic biology in regenerative medicine
    Angharad Evans, Elizabeth Ratcliffe · 2017 · Engineering Biology
  29. Nanotechnology Application and Intellectual Property Right Prospects of Mammalian Cell Culture
    Hari Krishnareddy Rachamalla, Anubhab Mukherjee, Manash Kumar Paul · 2021 · Biochemistry
  30. Insight into the pathogenesis of interstitial lung diseases and near-to-native lung fibrosis models
    Marianna Štefániková, Veronika Sedláková, Türkan Portakal, Aleš Hampl, Petr Vaňhara, Martina Doubková · 2025 · European journal of medical research
  31. Biomaterials in Organoid Development
    Asmak Abdul Samat, Badrul Hisham Yahaya · 2022 · Stem cell biology and regenerative medicine
  32. Cryopreservation of human lung tissue for 3D ex vivo analysis
    Nickolas G. Diodati, Ganlin Qu, Borna Mehrad, Matthew A Schaller · 2025 · Respiratory Research
  33. Pitfalls in developing new compounds for idiopathic pulmonary fibrosis
    Steven D. Nathan, Fernando J. Martínez · 2017 · Current Opinion in Pulmonary Medicine
  34. The Role of Advanced Technologies against COVID-19: Prevention, Detection, and Treatments
    Elham Hasanzadeh, Adele Rafati, Seyedeh Masoumeh Seyedhosseini Tamijani, Raheleh Rafaiee, Ali Golchin, Mozhgan Abasi · 2022 · Current Stem Cell Research & Therapy
  35. Recent Advancements in the Generation and Application of Therapeutic Cell Populations for Lung Epithelial Repair
    Muyang Zhou, Dana Brinson, Cindy Lei, Golnaz Karoubi · 2025 · Journal of Tissue Engineering and Regenerative Medicine
  36. Disease modeling and drug screening using human airway organoids: a systematic review
    Do Hyun Kim, Sung Won Kim · 2021 · Organoid
  37. 3D modeling of the lung in health and disease
    Ranu Surolia, K.G. Dsouza, Veena B. Antony · 2022 · Elsevier eBooks
  38. Advanced strategies in organoids for metabolic monitoring and metabolic disease modeling
    Wenjun Ma, Yongxin Xu, Zhifeng Gu, Dong Li · 2025 · Nano Research
  39. Next-Generation In Vitro Pulmonary Platforms for Respiratory Disease Modelling and Therapeutic Development: Current Advances and Future Prospects
    Fariya Khan, Pratibha Verma, Arun Kumar Singh, Manoj Kumar, Jalaj Gupta, Girijesh Kumar Patel, Samradhi Singh, Vinod Kumar, Alok Kumar Yadav, Vinod Verma · 2026 · Medicina
  40. Techniques to Produce and Culture Lung Tumor Organoids
    Cameron D. Yamanishi, Kimberly Jen, Shuichi Takayama · 2017 · Cancer drug discovery and develogment/Cancer drug discovery and development
  41. 3D culture of multipotent Sox9+ mouse embryonic lung progenitors: Isolation, Expansion and Cryopreservation
    Massimo Nichane, Massimo Nichane, Asif Javed, Sivakamasundari Vijayakumar, Monisha Ganesan, Lay Teng Ang, Petra Kraus, Thomas Lufkin, Kyle M. Loh, Bing Lim · 2017 · Protocol Exchange
  42. Introductory Chapter: Organoid Technology and Potential Applications
    Manash Kumar Paul · 2022 · Biomedical engineering
  43. Abacavir enhances the efficacy of doxorubicin via inhibition of histone demethylase KDM5B in breast cancer
    Anmi Jose, Pallavi Kulkarni, Naveena A. N. Kumar, Nawaz Usman, Gabriel Sunil Rodrigues, Gautham G. Shenoy, Rama Rao Damerla, Murali Munisamy, Bharti Bisht, Sooryanarayana Varambally et al. · 2025 · Scientific Reports
  44. InnovativeIn VitroModels for the Study of Lung Diseases
    Vittorio Picchio, Vittoria Cammisotto, Francesca Pagano, Roberto Carnevale, Isotta Chimenti · 2021 · IntechOpen eBooks
  45. Stem Cell-Based Organoid Models in Lung Development and Diseases
    Ahmed H. K. El-Hashash · 2018 · Springer eBooks
  46. Drug development using pancreatic and lung organoid models
    Minsig Choi, Meghan Bialt DeCelie, John D. Haley · 2019 · Elsevier eBooks
  47. Induced pluripotent stem cells
    Ben A. Calvert, Zareeb Lorenzana, Christiana N. Senger, Che-Yu Hsu, Shana M. Busch, Sinem Koç-Günel, Erik J. Quiroz, Amy L. Ryan · 2022 · Elsevier eBooks
  48. Lung Organoids: A New Pathway into Lung Regeneration and Repair
    Lu Tian, Chennan Carrie Zhang, Martha Rea-Moreno, Ya‐Wen Chen · 2022 · Stem cell biology and regenerative medicine
  49. Modelling of a wide variety of disease using adult stem cell-derived organoids
    Jelte Yoran van der Vaart · 2022
  50. Novel Approaches to Drug Discovery in Interstitial Lung Disease
    Laura Fabbri, Gisli R. Jenkins · 2020 · Elsevier eBooks
  51. Bioengineering Approaches for the Distal Lung
    Darcy Elizabeth Wagner · 2021 · Elsevier eBooks
  52. Evolution of Organoids in Oncology
    Allen Thayakumar Basanthakumar, Janitha Chandrasekhar Darlybai, Jyothsna Ganesh · 2022 · Biomedical engineering
  53. Development of an advanced multi-cellular and dynamic flow model of the human alveolar airway
    Duarte, Joana Amaral · 2022
  54. Pulmonary fibrosis: risk factors, pathogenesis and in vivo/in vitro experimental modeling
    Irena V. Chistyakova, Anna Malashicheva · 2023 · Genes and Cells
  55. Hydrogels in cell and tissue engineering
    Sarah Rajabi, Sadaf Vahdat, Fatemeh Ganji, Melika Parchehbaf Kashani, Fatemeh Safari, Ravin Narain · 2025 · Elsevier eBooks
  56. The Future of Precision Medicine in Interstitial Lung Disease
    Traci Nicole Adams, Chandni Patel, Mridu Gulati · 2025 · Respiratory medicine
  57. Current Advances in the use of Tumor Organoids in Lung Cancer Modeling and Precision Oncology
    Bharti Bisht, Arkaprabha Basu, Keshav S. Moharir, Swati Tripathi, Rohit Gundamaraju, Jyotirmoi Aich, Soumya Basu, Manash Kumar Paul · 2025 · BENTHAM SCIENCE PUBLISHERS eBooks
  58. Bioengineering Organoids for Disease Modeling and Drug Discovery
    Kaplana Mandal, Shalaka Wahane, Muhammad Nihad, Anubhab Mukherjee, Bharti Bisht, Chrianjay Mukhopadhyay, Bipasha Bose, Manash Kumar Paul · 2025 · BENTHAM SCIENCE PUBLISHERS eBooks
  59. Organoids: New Research Tool in Cancer Diagnostics and Therapeutics
    Pravin D. Potdar · 2025 · BENTHAM SCIENCE PUBLISHERS eBooks
  60. Additional file 1 of Organoids: a systematic review of ethical issues
    Dide de Jongh, Massey, Emma K., Eline Maria Bunnik · 2022 · Figshare
  61. Additional file 2 of Organoids: a systematic review of ethical issues
    Dide de Jongh, Massey, Emma K., Eline Maria Bunnik · 2022 · Figshare
  62. Modeling cell-cell interactions to advance drug discovery in Idiopathic Pulmonary Fibrosis
    Chandani Sen, Justin Langerman, Konstantinos–Dionysios Alysandratos, Andrea Brigitta Alber, Caroline L. Cherry, Kristen Castillo, Sarah Siegel, Rachana R. Chandran, WooSuk Choi, Tammy M. Rickabaugh et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  63. Next‐Generation Respiratory Models: Bridging the Gap Between Biology and Bioengineering
    Eun‐Ho Lee, Dong Hyuk Youn, Kang Song, Bumjun Park, Ji‐Hoon Lee, Byung‐Soo Kim, Yun Suk Huh, Sung‐Min Kang · 2026 · Advanced Healthcare Materials
  64. Optimisation du traitement du cancer du sein Triple-Négatif : développement des modèles de culture cellulaire en trois dimensions, efficacité de l'Olaparib (anti-PARP1) en combinaison avec la radiothérapie et chimiorésistance instaurée par les protéines Multi Drug Résistance
    Clémence Dubois · 2018
  65. Alveolar organoids: from model systems to applications in respiratory diseases
    Yuanfang Xing, Luyu Yang, Zhimin Cao, Dongchang Wang, Huan Ye · 2026 · Journal of Translational Medicine