The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Immunologic Abnormalities in Patients Receiving Multiple Blood Transfusions
Abstract
Concern for the potential risk of the acquired immunodeficiency syndrome among blood cell recipients led us to measure immunologic functions in patients who had received multiple transfusions. Abnormalities of two immunologic tests, natural killer cell function and helper/suppressor (T4/T8) lymphocyte subpopulation ratio, have characterized patients with the acquired immunodeficiency syndrome and are prevalent in populations at risk for this syndrome. Natural killer cell function was severely depressed in multiply transfused patients. However, T4/T8 ratios were normal in this population. The role of chronic antigenic stimulation was studied by measurement of HLA-DR expression on T cells. The expression of HLA-DR antigen is markedly elevated in multiply transfused patients. These results show that chronic exposure to foreign antigens may be associated with abnormalities of immunologic function, but that chronically transfused patients do not have the same immunologic profile as reported in some homosexuals and hemophiliacs.
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Cites
Gottlieb, M. S., Schroff, R., Schanker, H. M., Weisman, J. D., Fan, P. T., Wolf, R. A., & Saxon, A. (1981) · New England Journal of Medicine · doi:10.1056/nejm198112103052401 · Cited by 2,728
Natural Killer Cells: Their Roles in Defenses Against Disease
Herberman, R. B., & Ortaldo, J. R. (1981) · Science · doi:10.1126/science.7025208 · Cited by 1,336
Disseminated Kaposi's Sarcoma in Homosexual Men
FRIEDMAN-KIEN, A. E., LAUBENSTEIN, L. J., RUBINSTEIN, P., BUIMOVICI-KLEIN, E., MARMOR, M., STAHL, R., SPIGLAND, I., KIM, K. S., & ZOLLA-PAZNER, S. (1982) · Annals of Internal Medicine · doi:10.7326/0003-4819-96-6-693 · Cited by 717
Ko, H. S., Fu, S. M., Winchester, R. J., Yu, D. T., & Kunkel, H. G. (1979) · The Journal of experimental medicine · doi:10.1084/jem.150.2.246 · Cited by 439
ACQUIRED IMMUNODEFICIENCY IN AN INFANT: POSSIBLE TRANSMISSION BY MEANS OF BLOOD PRODUCTS
Ammann, A., Wara, D., Dritz, S., Cowan, M., Weintrub, P., Goldman, H., & Perkins, H. (1983) · The Lancet · doi:10.1016/s0140-6736(83)92082-2 · Cited by 380
Warner, J. F., & Dennert, G. (1982) · Nature · doi:10.1038/300031a0 · Cited by 224
Increased Circulating Ia-Antigen-Bearing T Cells in Type I Diabetes Mellitus
Jackson, R. A., Morris, M. A., Haynes, B. F., & Eisenbarth, G. S. (1982) · New England Journal of Medicine · doi:10.1056/nejm198204013061305 · Cited by 222
Interferons with Special Emphasis on the Immune System
Friedman, R. M., & Vogel, S. N. (1983) · Advances in Immunology · doi:10.1016/s0065-2776(08)60378-8 · Cited by 201
Viruses and bone marrow failure
Young, N., & Mortimer, P. (1984) · Blood · doi:10.1182/blood.v63.4.729.bloodjournal634729 · Cited by 171
Self-citationAllogeneic Leukocytes as a Possible Factor in Induction of AIDS in Homosexual Men
Shearer, G. M. (1983) · New England Journal of Medicine · doi:10.1056/nejm198301273080415 · Cited by 71
Cited by
Circulating Activated Suppressor T Lymphocytes in Aplastic Anemia
Zoumbos, N. C., Gascón, P., Djeu, J. Y., Trost, S. R., & Young, N. S. (1985) · New England Journal of Medicine · doi:10.1056/nejm198501313120501 · Cited by 339
Self-citationZoumbos, N. C., Gascon, P., Djeu, J. Y., & Young, N. S. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.1.188 · Cited by 330
Self-citationHenry, D. H., Beall, G. N., Benson, C. A., Carey, J., Cone, L. A., Eron, L. J., Fiala, M., Fischl, M. A., Gabin, S. J., Gottlieb, M. S., et al. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-117-9-739 · Cited by 180
Metadata
- Authors
- GASCÓN, P., ZOUMBOS, N. C., & YOUNG, N. S.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1984-02-01
- Volume
- 100
- Issue
- 2
- Pages
- 173-177
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2092291251
- Cited by
- 305
- References
- 12
- FWCI
- 4.78
- Type
- journal article
- Language
- en
- Open access
- closed
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- GASCÓN, P., ZOUMBOS, N. C., & YOUNG, N. S. (1984). Immunologic Abnormalities in Patients Receiving Multiple Blood Transfusions. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-100-2-173
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
