The DOI matches its Crossref record.
Identification of Major Prognostic Subgroups of Patients with Large-Cell Lymphoma Treated with m-BACOD or M-BACOD
Abstract
One hundred twenty-one patients with diffuse large-cell lymphoma treated with m- or M-BACOD (methotrexate, bleomycin, doxorubicin, cyclophosphamide, vincristine, and dexamethasone) were evaluated for pretreatment characteristics predictive for response and survival. Two characteristics, poor performance status and massive bulky disease, were negatively associated with response rate in a multivariate analysis. These two characteristics were also negatively associated with survival in multivariate analysis, as was another factor, an increased number of extranodal sites of disease. These three pretreatment characteristics were used to construct a model containing 12 categories of patients at increasing risk for relapse and shortened survival. These categories divided naturally into three broad groups of patients with respective 5-year survival rates of 68%, 55%, and 24%.
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Citations
Cited by
A Predictive Model for Aggressive Non-Hodgkin's Lymphoma
(1993) · New England Journal of Medicine · doi:10.1056/nejm199309303291402 · Cited by 4,949
Gianni, A. M., Bregni, M., Siena, S., Brambilla, C., Di Nicola, M., Lombardi, F., Gandola, L., Tarella, C., Pileri, A., Ravagnani, F., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199705013361804 · Cited by 470
Vose, J. M., Link, B. K., Grossbard, M. L., Czuczman, M., Grillo-Lopez, A., Gilman, P., Lowe, A., Kunkel, L. A., & Fisher, R. I. (2001) · Journal of Clinical Oncology · doi:10.1200/jco.2001.19.2.389 · Cited by 417
Sociodemographic factors and quality of life as prognostic indicators in head and neck cancer
de Graeff, A., de Leeuw, J. R. J., Ros, W. J. G., Hordijk, G. J., Blijham, G. H., & Winnubst, J. A. M. (2001) · European Journal of Cancer · doi:10.1016/s0959-8049(00)00385-3 · Cited by 199
Metadata
- Authors
- SHIPP, M. A., HARRINGTON, D. P., KLATT, M. M., JOCHELSON, M. S., PINKUS, G. S., MARSHALL, J. L., ROSENTHAL, D. S., SKARIN, A. T., & CANELLOS, G. P.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1986-06-01
- Volume
- 104
- Issue
- 6
- Pages
- 757-765
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2075732668
- Cited by
- 277
- References
- 0
- FWCI
- 14.55
- Type
- journal article
- Language
- en
- Open access
- closed
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- SHIPP, M. A., HARRINGTON, D. P., KLATT, M. M., JOCHELSON, M. S., PINKUS, G. S., MARSHALL, J. L., ROSENTHAL, D. S., SKARIN, A. T., & CANELLOS, G. P. (1986). Identification of Major Prognostic Subgroups of Patients with Large-Cell Lymphoma Treated with m-BACOD or M-BACOD. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-104-6-757
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
