The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Medical Futility: Its Meaning and Ethical Implications
Abstract
The notion of medical futility has quantitative and qualitative roots that offer a practical approach to its definition and application. Applying these traditions to contemporary medical practice, we propose that when physicians conclude (either through personal experience, experiences shared with colleagues, or consideration of published empiric data) that in the last 100 cases a medical treatment has been useless, they should regard that treatment as futile. If a treatment merely preserves permanent unconsciousness or cannot end dependence on intensive medical care, the treatment should be considered futile. Unlike decision analysis, which defines the expected gain from a treatment by the joint product of probability of success and utility of outcome, our definition of futility treats probability and utility as independent thresholds. Futility should be distinguished from such concepts as theoretical impossibility, such expressions as "uncommon" or "rare," and emotional terms like "hopelessness." In judging futility, physicians must distinguish between an effect, which is limited to some part of the patient's body, and a benefit, which appreciably improves the person as a whole. Treatment that fails to provide the latter, whether or not it achieves the former, is "futile". Although exceptions and cautions should be borne in mind, we submit that physicians can judge a treatment to be futile and are entitled to withhold a procedure on this basis. In these cases, physicians should act in concert with other health care professionals, but need not obtain consent from patients or family members.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The sad conse-quences of not telling the truth regarding a cancer include depriving the patient of an opportunity for completion of important life-tasks”
From Principles of Clinical Ethics and Their Application to Practice (2021) · cites this paper as [21]
Citations
Cites
Knaus, W. A., Draper, E. A., Wagner, D. P., & Zimmerman, J. E. (1985) · Critical Care Medicine · doi:10.1097/00003246-198510000-00009 · Cited by 15,518
APACHE II-A Severity of Disease Classification System
Knaus, W. A., Draper, E. A., Wagner, D. P., & Zimmerman, J. E. (1986) · Critical Care Medicine · doi:10.1097/00003246-198608000-00028 · Cited by 13,379
Beecher, H. K. (1955) · JAMA · doi:10.1001/jama.1955.02960340022006 · Cited by 1,850
Freiman, J. A., Chalmers, T. C., Smith, H., & Kuebler, R. R. (1978) · New England Journal of Medicine · doi:10.1056/nejm197809282991304 · Cited by 1,628
An Evaluation of Outcome from Intensive Care in Major Medical Centers
Knaus, W. A., DRAPER, E. A., WAGNER, D. P., & ZIMMERMAN, J. E. (1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-104-3-410 · Cited by 1,191
Survival after Cardiopulmonary Resuscitation in the Hospital
Bedell, S. E., Delbanco, T. L., Cook, E. F., & Epstein, F. H. (1983) · New England Journal of Medicine · doi:10.1056/nejm198309083091001 · Cited by 860
The Physician's Responsibility toward Hopelessly Ill Patients
Wanzer, S. H., Adelstein, S. J., Cranford, R. E., Federman, D. D., Ed, H., Cg, M., Safar, P. J., Stone, A. A., Taussig, H. B., & van Eys, J. (1984) · New England Journal of Medicine · doi:10.1056/nejm198404123101505 · Cited by 427
In-Hospital Cardiopulmonary Resuscitation
Taffet, G. E. (1988) · JAMA · doi:10.1001/jama.1988.03410140081027 · Cited by 412
Outcomes of Cardiopulmonary Resuscitation in the Elderly
Murphy, D. J., Murray, A. M., Robinson, B. E., & Campion, E. W. (1989) · Annals of Internal Medicine · doi:10.7326/0003-4819-111-3-199 · Cited by 368
Blackhall, L. (1987) · New England Journal of Medicine · doi:10.1056/nejm198711123172009 · Cited by 368
Research works printed but not linked: 10
- . Deciding to Forego Life-Sustaining Treatment: A Report on the Ethical, Medical, and Legal Issues in Treatment Decisions. Washington DC: U.S. Government Printing Office; 1983:60-89.
- Jonsen A, 1987, Pharos., 50, 4
- Lo B, 1989, The Meaning of AIDS, 1, 86
- Weinstein M, 1980, Clinical Decision Analysis.
- Jonsen A . The Old Ethics and the New Medicine. Cambridge: Harvard University Press; 1990.
- 1977, Ethics in Medicine: Historical Perspectives and Contemporary Concerns., 6
- 1981, Republic., 76
- Plum F, 1980, The Diagnosis of Stupor and Coma.
- Katz J, 1984, The Silent World of Doctor and Patient.
- Jecker N, 1990, J Clin Med.
Cited by
Sorted by citations
Items 901–1,000 of 1,000
How Ethics Can Support Clinicians Caring for Critically Ill Patients
Milliken, A. B., & Sadovnikoff, N. (2020) · Springer eBooks · doi:10.1007/978-3-030-43127-3_1 · Cited by 1
Exposing futility by searching beneath the concept
Richards, S. (2020) · Clinical Ethics · doi:10.1177/1477750920983577 · Cited by 1
Ethical Considerations in the Use of Technology in the Cardiac Intensive Care Unit
Hofmann, B. (2021) · Springer eBooks · doi:10.1007/978-3-030-80112-0_13 · Cited by 1
Medical Futility: Choosing the Next Intervention
Myers, R. K., & Weir, A. (2022) · Southern Medical Journal · doi:10.14423/smj.0000000000001351 · Cited by 1
Hakan Volkan, A. C. A. R. (2016) · Turkish Journal of Bioethics · doi:10.5505/tjob.2016.77486 · Cited by 1
Neuro-Oncological Problems in the Intensive Care Unit
Bindu, B., Mahajan, C., Kapoor, I., & Prabhakar, H. (2022) · Springer eBooks · doi:10.1007/978-981-16-9929-0_32 · Cited by 1
principio terapéutico frente al potenciamiento cognitivo mediante fármacos
Pazos, L. S. (2023) · Medicina y Ética · doi:10.36105/mye.2023v34n3.02 · Cited by 1
Respect for Patient Autonomy: A Patient Perspective
Adwedaa, E. (2022) · Postgraduate Medical Journal of Ghana · doi:10.60014/pmjg.v4i1.82 · Cited by 1
End of Life: Ethical and Legal Considerations
Devictor, D. J., Mokhtari, M., & Tissières, P. (2013) · Springer eBooks · doi:10.1007/978-1-4471-4619-3_170 · Cited by 1
Ethical and Policy Issues in End-of-Life Care
Bottrell, M. M., Cassel, C. K., & Felzenberg, E. R. (2006) · Springer eBooks · doi:10.1007/0-387-22621-4_86 · Cited by 1
Enjeux éthiques en neuroréanimation
Baumann, A., & Puybasset, L. (2013) · Cited by 1
Mission statements: politically correct or countercultural?
Fitzpatrick, A., & Gaylor, C. C. (1994) · PubMed · Cited by 1
Futility in Emergency Medicine
Derse, A. R. (2012) · doi:10.1002/9781118292150.ch11 · Cited by 1
Termination of resuscitation in the out‐of‐hospital setting
Morrison, L. J., Drennan, I. R., & Verbeek, P. R. (2015) · Emergency medical services · doi:10.1002/9781118990810.ch65 · Cited by 1
Rie, M. A. (1995) · Philosophy and medicine · doi:10.1007/978-94-011-0259-9_3 · Cited by 1
Berger, R. (2002) · Springer eBooks · doi:10.1007/978-1-4615-0939-4_18 · Cited by 1
Ban, K., & Rosen, P. L. (2006) · Internal and Emergency Medicine · doi:10.1007/bf02934743 · Cited by 1
Commentary: Weighing and Comparing Expert Testimony by Medical Ethicists
Schneiderman, L. J. (2000) · The Journal of Law Medicine & Ethics · doi:10.1111/j.1748-720x.2000.tb00665.x · Cited by 1
Self-citationLuce, J. M. (2007) · Critical Care Medicine · doi:10.1097/01.ccm.0000262395.14521.77 · Cited by 1
DNR policies in North America: A procedural morass - resuscitation practices revisited
Puri, V. K. (2006) · Indian Journal of Critical Care Medicine · doi:10.4103/0972-5229.24688 · Cited by 1
MATTERS OF LIFE AND DEATH: MAKING MORAL THEORY WORK IN MEDICAL ETHICS AND THE LAW
Cowan, D. H. (2002) · Journal of Legal Medicine · doi:10.1080/01947640290050292 · Cited by 1
Ethische Aspekte der geriatrischen Onkologie
Meran, J. G., & Widder, J. (2002) · Der Onkologe · doi:10.1007/s00761-001-0274-8 · Cited by 1
Jecker, N. S. (1992) · HEC Forum · doi:10.1007/bf00057791 · Cited by 1
Self-citationPatient care decision‐making: A legal guide for providers
Gregory, D. R. (1992) · Journal of Legal Medicine · doi:10.1080/01947649209510897 · Cited by 1
Case Studies in Medical Futility
Mains, D. A., Coustasse, A., & Lurie, S. G. (2008) · Journal of Hospital Marketing & Public Relations · doi:10.1300/j375v18n01_05 · Cited by 1
Checchia, P. A., Sehra, R., Daher, N. S., Chinnock, R., & Bailey, L. L. (2004) · The Journal of Heart and Lung Transplantation · doi:10.1016/s1053-2498(03)00116-5 · Cited by 1
Problems in the Care of the Terminally Ill
Loewy, E. H. (1989) · Springer eBooks · doi:10.1007/978-94-017-4479-9_10 · Cited by 1
Disaggregating Data: From Groups to Individuals
Carlet, J. M., Montuclard, L., & Garrouste-Orgeas, M. (2002) · Springer eBooks · doi:10.1007/978-1-4615-6939-8_22 · Cited by 1
Doig, G. S. (1999) · Library and Archives Canada (Government of Canada) · Cited by 1
Chen, Y. (2009) · OhioLink ETD Center (Ohio Library and Information Network) · Cited by 1
Catholic Teaching on Life and the Challenge of the HIV/AIDS Crisis in Sub-Saharan Africa
Saidi, E. (2004) · The Linacre Quarterly · doi:10.1080/20508549.2004.11877698 · Cited by 1
Cummins, R. O. (1992) · Journal of General Internal Medicine · doi:10.1007/bf02599465 · Cited by 1
Ethics, distribution and Oregon
Gaut, B. D. (1993) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1993.tb137837.x · Cited by 1
Medical futility and the critically ill patient.
Ll, L., & Lj, K. (1999) · PubMed · Cited by 1
End-of-life Care: Challenges and Obligations in Setting Limits to Life-sustaining Therapy
Lee, A. O. K. (2003) · Annals of the Academy of Medicine Singapore · doi:10.47102/annals-acadmedsg.v32n6p785 · Cited by 1
Medical Futility in the New Millennium: Our View
van Heerden, P. V., Solomon, M., & Roberts, B. L. (1999) · Yearbook of intensive care and emergency medicine · doi:10.1007/978-3-662-13453-5_61 · Cited by 1
Letting vegetative patients die
Jennett, B. (1995) · Cambridge University Press eBooks · doi:10.1017/cbo9780511663444.014 · Cited by 1
PEDIATRIC CARDIOPULMONARY RESUSCITATION
Schleien, C. L., Gelman, B., & Kuluz, J. W. (1995) · Anesthesiology Clinics of North America · doi:10.1016/s0889-8537(21)00589-7 · Cited by 1
(2005) · The Internet Journal of Pain Symptom Control and Palliative Care · doi:10.5580/1883 · Cited by 1
Withdrawal of life-sustaining therapy: the case for delay
Foex, B. A. (2016) · Emergency Medicine Journal · doi:10.1136/emermed-2016-206397 · Cited by 1
Etiske valg ved medisinsk nytteløs behandling
Miljeteig, I., Johansson, K. A., & Norheim, O. F. (2008) · Tidsskrift for Den Norske Laegeforening · Cited by 1
Young, R. (2011) · Oxford University Press eBooks · doi:10.1093/obo/9780195396577-0042 · Cited by 1
Ethical Considerations in Managing Critically Ill Patients
Danis, M., Emanuel, E. E., & SILVERMAN, H. J. (2008) · Elsevier eBooks · doi:10.1016/b978-032304841-5.50074-1 · Cited by 1
Reliable neurological prediction after cardiac arrest — Are we willing to pay the price?
Cronberg, T., & Nolan, J. P. (2019) · Resuscitation · doi:10.1016/j.resuscitation.2019.04.040 · Cited by 1
Abd‐Allah, S., & Checchia, P. A. (2008) · Springer eBooks · doi:10.1007/978-1-84800-923-3_24 · Cited by 1
Blasimme, A. (2022) · Pathy's Principles and Practice of Geriatric Medicine · doi:10.1002/9781119484288.ch116 · Cited by 1
Intensive Care Foundation Research Free Paper Presentations
(2013) · Journal of the Intensive Care Society · doi:10.1177/17511437130141s101 · Cited by 1
Kopelman, L. M. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-373932-2.00154-x · Cited by 1
Wilkinson, D. J. C. (2017) · The International Encyclopedia of Ethics · doi:10.1002/9781444367072.wbiee839 · Cited by 1
The Need for Consistency in NICUs
Weir, R. F. (1992) · The Journal of Clinical Ethics · doi:10.1086/jce199203418 · Cited by 1
U.S. Catholic Bishops on Nutrition and Hydration: A Second Opinion
Connors, R. B. (1993) · The Journal of Clinical Ethics · doi:10.1086/jce199304310 · Cited by 1
Weir, R. F. (1992) · The Journal of Clinical Ethics · doi:10.1086/jce199203310 · Cited by 1
End-of-Life Decisionmaking in the Veterans Health Administration
Berkowitz, K. A. (1997) · HEC Forum · doi:10.1023/a:1008831223382 · Cited by 1
Mantenimiento del soporte vital o tratamiento de postergación de la muerte en la UCI pediátrica
Devictor, D., Latour, J. M., & Tissières, P. (2008) · Clínicas pediátricas de Norteamérica · Cited by 1
Arnold, R. M. (2007) · Springer eBooks · doi:10.1007/978-1-4020-6260-5_9
Ethical Issues in the Neurointensive Care Unit
Allen, W. (2013) · Springer eBooks · doi:10.1007/978-1-4471-5226-2_45
Bioethical Issues in the Neurosciences Critical Care Unit
Suarez, J. I., & Youngner, S. J. (2004) · Humana Press eBooks · doi:10.1007/978-1-59259-660-7_15
Sokol, D. K. (2011) · SpringerBriefs in ethics · doi:10.1007/978-94-007-2783-0_5
Toney, S. (2022) · Digital Archive @ GSU · doi:10.57709/1062309
Limitations et arrêts de traitements à la phase aigu vasculaires cérébraux graves
Crozier, S. (2010) · Springer eBooks · doi:10.1007/978-2-287-99072-4_41
Social, ethical and legal issues in chronic hemodialysis and transplantation
Patel, S. S., & Kimmel, P. L. (2004) · Springer eBooks · doi:10.1007/978-1-4020-2275-3_54
Physicians' Disagreements About Life-Sustaining Treatments: A Case Study
Gordon, E. J., & Weiss, A. H. (1999) · HEC Forum · doi:10.1023/a:1008939908311
Infertility Treatment in Perimenopausal Women: Ethical Considerations
Browne, H. N., Armstrong, A. Y., & DeCherney, A. H. (2008) · Cambridge University Press eBooks · doi:10.1017/cbo9780511547287.075
The hospitalized prisoner with a life-threatening illness: criminal first and patient second?
Badger, J. M., Ladd, R. E., & Friedemann, G. R. (2012) · PubMed · doi:10.1097/nhl.0b013e3182570904
Therapiebegrenzung und Therapieabbruch in der Intensivmedizin
Junginger, T. (2008) · Springer eBooks · doi:10.1007/978-3-540-75820-4_15
No intentar la reanimación en pediatría
Morrison, W. E., & Berkowitz, I. (2007) · Clínicas pediátricas de Norteamérica
Simon, A. F. (2003) · Internet Journal of Allied Health Sciences and Practice · doi:10.46743/1540-580x/2003.1021
Should Patient B Receive Critical Care?
Vincent, J. (2002) · Springer eBooks · doi:10.1007/978-1-4615-0939-4_19
A Multilevel Examination of a Critically Ill Patient
Kilcullen, J. K. (2002) · Springer eBooks · doi:10.1007/978-1-4615-0939-4_17
Dilemas éticos en perinatología
Gómez-Gómez, C., Danglot-Banck, C., & Gómez, M. G. (2005)
Ethical Issues in the Care of Patients With Hematologic Diseases
Hook, C. C. (2001) · Humana Press eBooks · doi:10.1007/978-1-59259-228-9_29
The Arguments for Euthanasia and Physician-Assisted Suicide: Catholic Response
Rodriguez, E. (2003) · The Linacre Quarterly · doi:10.1080/20508549.2003.11877664
Couper, K. (2026) · Warwick Research Archive Portal (University of Warwick) · doi:10.82444/warw.33689812
Pace, N. A. (1993) · Current Anaesthesia and Critical Care · doi:10.1016/0953-7112(93)90016-7
CE: “Medically futile” treatments require more than going to court
Trotochaud, K. (2006) · The Case Manager · doi:10.1016/j.casemgr.2006.04.009
Markman, M. M. (2010) · Case Reports in Oncology · doi:10.1159/000295905
Circulation Cardiovascular Case Series
Beckman, J. A., & Loscalzo, J. (2010) · Circulation · doi:10.1161/circulationaha.110.989160
Campanini, G. E. M., Fontanella, A., Nozzoli, C., Mazzone, A., & Nardi, R. (2014) · Italian Journal of Medicine · doi:10.4081/itjm.q.2014.1
End-of-Life Decision Making in the Intensive Care Unit
Siegel, M. D. (2008) · Clinical Pulmonary Medicine · doi:10.1097/cpm.0b013e31818cd412
The Outpatient Management of a Brain Dead Child
Stidham, G. L., Goldworth, A., Joralemon, G., Bennahum, D. A., & Ivanjushkin, A. (1993) · Cambridge Quarterly of Healthcare Ethics · doi:10.1017/s0963180100004370
Meilaender, G. C. (2014) · Journal of the Society of Christian Ethics · doi:10.1353/sce.2014.0040
Convergent Expert Views on Decision-Making for Decompressive Craniectomy in Malignant MCA Syndrome
Mendelsohn, D. A., Haw, C. S., & Illes, J. (2014) · Neuroethics · doi:10.1007/s12152-014-9206-3
Ethical Issues and the Allocation of Scarce Resources During a Public Health Emergency
Siegel, M. D. (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-150-12-200906160-00018
Should a patient in persistent vegetative state live?
Asai, A. (1999) · Bioethics News · doi:10.1007/bf03351220
Easing the burden of decisionmaking in futile situations
Holden, C. M. (1995) · HEC Forum · doi:10.1007/bf01463303
Privacy Beliefs and the Violent Family
Baughan, D. M. (1993) · JAMA · doi:10.1001/jama.1993.03500230068025
Marinelli, R. D. (1994) · Activities Adaptation & Aging · doi:10.1300/j016v18n03_05
The question of futility and Roger C. Bone
Bitsori, M., Georgopoulos, D., & Galanakis, E. (2009) · Medicine Health Care and Philosophy · doi:10.1007/s11019-009-9196-9
The above letter was referred to the author of the original paper, and Dr. Finucane's reply follows
Finucane, T. E. (1991) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1991.tb03587.x
Los Comités Asistenciales de Ética: ¿necesarios o prescindibles?
Romero, J. M. C., & Solsona, J. F. (2004) · Medicina Intensiva · doi:10.1016/s0210-5691(04)70082-0
Privacy Beliefs and the Violent Family-Reply
Jecker, N. S. (1993) · JAMA · doi:10.1001/jama.1993.03500230068026
Self-citationA Very Bad Prognosis for Awakening from Coma
Robinson, L. R. (2007) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0b013e31805b8397
Ethical decision making in the care of seriously ill and dying patients. Theory and practice
Latimer, E. J. (1995) · Springer eBooks · doi:10.1007/978-1-4757-0136-4_28
Out-of-hospital cardiac arrests in older age groups
Deasy, C. (2011) · Journal of Paramedic Practice · doi:10.12968/jpar.2011.3.12.690
Feenstra, R., Schuur, T., & ter Avest, E. (2014) · Huisarts en Wetenschap · doi:10.1007/s12445-014-0102-1
CARE OF TERMINALLY ILL CANCER PATIENTS: A TERTIARY CARE CENTRE SCENARIO IN BHOPAL
Ratre, B. K., & Jain, R. (2013) · International Journal of Pharma and Bio Sciences
Arandomized trial ofethics education for medical houseofficers
PSulmasy, D. (1993)
Metadata
- Authors
- Schneiderman, L. J., Jecker, N. S., & Jonsen, A. R.
- Affiliations
- University of California San Diego (US)
- Corresponding author
- Schneiderman, Lawrence J.
- ORCID
- Jecker, Nancy S.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1990-06-15
- Volume
- 112
- Issue
- 12
- Pages
- 949-954
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2067149985
- Cited by
- 1,215
- References
- 28
- Citations by year
- 2026: 28 · 2025: 29 · 2024: 46 · 2023: 35 · 2022: 38 · 2021: 36 · 2020: 41 · 2019: 55 · 2018: 40 · 2017: 33 · 2016: 39 · 2015: 43 · 2014: 39 · 2013: 44 · 2012: 41
- FWCI
- 15.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics and bioethics in healthcare
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Ethics and Legal Issues in Pediatric Healthcare
- Keywords
- futility, treatment decision-making, withholding treatment, decision analysis, physician judgment, informed consent, end-of-life care
- MeSH terms
- Critical Care, Ethics, Medical, Euthanasia, Passive, Family, Humans, Patient Participation, Philosophy, Medical, Physician's Role, Probability, Risk Assessment, Patient Selection, Personal Autonomy, Paternalism, Moral Obligations, Withholding Treatment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review