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Cited by 72Bariatric Surgery and OutcomesBody Contouring and SurgeryMinimally Invasive Surgical Techniques

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

Treatment of Mild to Moderate Obesity with Laparoscopic Adjustable Gastric Banding or an Intensive Medical Program: A Randomized Trial

O'Brien, Paul E., Dixon, John B., Laurie, Cheryl, Skinner, Stewart, Proietto, Joe, McNeil, John, Strauss, Boyd, Marks, Sharon, Schachter, Linda, Chapman, Leon, Anderson, Margaret·2006·Annals of Internal Medicine
DOI 10.7326/0003-4819-144-9-200605020-00005
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Abstract

Background: Obesity is a major, growing health problem. Observational studies suggest that bariatric surgery is more effective than nonsurgical therapy, but no randomized, controlled trials have confirmed this. Objective: To ascertain whether surgical therapy for obesity achieves better weight loss, health, and quality of life than nonsurgical therapy. Design: Randomized, controlled trial. Setting: University departments of medicine and surgery and an affiliated private hospital. Patients: 80 adults with mild to moderate obesity (body mass index, 30 kg/m2 to 35 kg/m2) from the general community. Interventions: Patients were assigned to a program of very-low-calorie diets, pharmacotherapy, and lifestyle change for 24 months (nonsurgical group) or to placement of a laparoscopic adjustable gastric band (LAP-BAND System, INAMED Health, Santa Barbara, California) (surgical group). Measurements: Outcome measures were weight change, presence of the metabolic syndrome, and change in quality of life at 2 years. Results: At 2 years, the surgical group had greater weight loss, with a mean of 21.6% (95% CI, 19.3% to 23.9%) of initial weight lost and 87.2% (CI, 77.7% to 96.6%) of excess weight lost, while the nonsurgical group had a loss of 5.5% (CI, 3.2% to 7.9%) of initial weight and 21.8% (CI, 11.9% to 31.6%) of excess weight (P < 0.001). The metabolic syndrome was initially present in 15 (38%) patients in each group and was present in 8 (24%) nonsurgical patients and 1 (3%) surgical patient at the completion of the study (P < 0.002). Quality of life improved statistically significantly more in the surgical group (8 of 8 subscores of Short Form-36) than in the nonsurgical group (3 of 8 subscores). Limitations: The study included mildly and moderately obese participants, was not powered for comparison of adverse events, and examined outcomes only for 24 months. Conclusions: Surgical treatment using laparoscopic adjustable gastric banding was statistically significantly more effective than nonsurgical therapy in reducing weight, resolving the metabolic syndrome, and improving quality of life during a 24-month treatment program.

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Crossref · 10.7326/0003-4819-144-9-200605020-00005

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Research works printed but not linked: 2

  1. 10.1001/jama.287.3.356 · DOI · Paper page
  2. 10.1016/S0039-6060(03)00392-1 · DOI · Paper page

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Metadata

Authors
O'Brien, P. E., Dixon, J. B., Laurie, C., Skinner, S., Proietto, J., McNeil, J., Strauss, B., Marks, S., Schachter, L., Chapman, L., & Anderson, M.
Affiliations
  • From Monash University and University of Melbourne, Melbourne, Victoria, Australia.
  • The University of Melbourne (AU)
ORCID
Venue
Annals of Internal Medicine
Publisher
American College of Physicians
Published
2006-05-02
Volume
144
Issue
9
Pages
625-633
ISSN
  • 0003-4819 (ISSN-L)
  • 1539-3704
DOI
10.7326/0003-4819-144-9-200605020-00005
OpenAlex
W1528885340
Cited by
46
References
30
Citations by year
2020: 1 · 2019: 1 · 2017: 2 · 2015: 2 · 2014: 2 · 2013: 6 · 2012: 2
FWCI
7.41
Type
journal article
Language
en
Open access
closed
Licence
www.acpjournals.org/journal/aim/text-and-data-mining (tdm)
Locations
  • Annals of Internal Medicine (publishedVersion)
  • Annals of Internal Medicine
Topics
  • Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
  • Health Sciences › Medicine › Surgery › Body Contouring and Surgery
  • Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
Keywords
laparoscopic adjustable gastric banding, bariatric surgery, very low calorie diet, pharmacotherapy, lifestyle intervention, weight loss, metabolic syndrome, quality of life, excess weight loss

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