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Cited by 217

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Plasma Levels of Norepinephrine

KOPIN, IRWIN J., LAKE, RAYMOND C., ZIEGLER, MICHAEL·1978·Annals of Internal Medicine

Abstract

Plasma norepinephrine derives from sympathetic nerves, but the proportion reaching the circulation before being metabolized varies with the type of nerve ending-effector junctions in the tissue. Plasma levels of norepinephrine also will fluctuate because of rapid metabolism rates and environmental, emotional, and endogenous stimuli provoking a sympathetic response. The responses of plasma catecholamines in spontaneously hypertensive rats and in normotensive rats of the same strain were compared after exposure to a variety of stressors. Drugs that inhibit monoamine oxidase, catechol-O-methyl transferase, or neuronal uptake were administered to show the effects of metabolic enzymes and neuronal uptake on the amounts of catecholamines reaching the circulation. Sympathetic nervous activity and the ability of the sympathetic nervous system to respond to a uniform stimulus are studied in hypertensive and normotensive subjects. A survey of the plasma levels of norepinephrine in a variety of neurologic disorders is given.

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Crossref · 10.7326/0003-4819-88-5-671

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Metadata

Authors
KOPIN, I. J., LAKE, R. C., & ZIEGLER, M.
Venue
Annals of Internal Medicine
Published
1978-05-01
Volume
88
Issue
5
Pages
671-680
ISSN
  • 0003-4819 (ISSN-L)
  • 1539-3704
OpenAlex
W2003560001
Cited by
217
References
2
FWCI
17.46
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Plasma Levels of Norepinephrine. https://app.cochat.ai/papers/10.7326/0003-4819-88-5-671
The paper
KOPIN, I. J., LAKE, R. C., & ZIEGLER, M. (1978). Plasma Levels of Norepinephrine. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-88-5-671

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.