The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Stress induced gene expression drives transient DNA methylation changes at adjacent repetitive elements
Open accessAbstract
Cytosine DNA methylation (mC) is a genome modification that can regulate the expression of coding and non-coding genetic elements. However, little is known about the involvement of mC in response to environmental cues. Using whole genome bisulfite sequencing to assess the spatio-temporal dynamics of mC in rice grown under phosphate starvation and recovery conditions, we identified widespread phosphate starvation-induced changes in mC, preferentially localized in transposable elements (TEs) close to highly induced genes. These changes in mC occurred after changes in nearby gene transcription, were mostly DCL3a-independent, and could partially be propagated through mitosis, however no evidence of meiotic transmission was observed. Similar analyses performed in Arabidopsis revealed a very limited effect of phosphate starvation on mC, suggesting a species-specific mechanism. Overall, this suggests that TEs in proximity to environmentally induced genes are silenced via hypermethylation, and establishes the temporal hierarchy of transcriptional and epigenomic changes in response to stress.
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DNA methylation patterns and epigenetic memory
Bird, A. (2002) · Genes & Development · doi:10.1101/gad.947102 · Cited by 7,124
Differential analysis of gene regulation at transcript resolution with RNA-seq
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Global epigenomic reconfiguration during mammalian brain development
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Self-citationConservation and divergence of methylation patterning in plants and animals
Feng, S., Cokus, S. J., Zhang, X., Chen, P.-Y., Bostick, M., Goll, M. G., Hetzel, J., Jain, J., Strauss, S. H., Halpern, M. E., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002720107 · Cited by 1,285
Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state
Crevillén, P., Yang, H., Cui, X., Greeff, C., Trick, M., Qiu, Q., Cao, X., & Dean, C. (2014) · Nature · doi:10.1038/nature13722 · Cited by 280
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Epigenetic regulation in plant abiotic stress responses
Chang, Y., Zhu, C., Jiang, J., Zhang, H., Zhu, J., & Duan, C. (2020) · Journal of Integrative Plant Biology · doi:10.1111/jipb.12901 · Cited by 533
Dynamics of dna methylation and its functions in plant growth and development
Kumar, S., & Mohapatra, T. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.596236 · Cited by 227
Revisiting the Relationship between Transposable Elements and the Eukaryotic Stress Response
Horváth, V., Merenciano, M., & González, J. (2017) · Trends in Genetics · doi:10.1016/j.tig.2017.08.007 · Cited by 219
Heritable Epigenomic Changes to the Maize Methylome Resulting from Tissue Culture
Han, Z., Crisp, P. A., Stelpflug, S., Kaeppler, S. M., Li, Q., & Springer, N. M. (2018) · Genetics · doi:10.1534/genetics.118.300987 · Cited by 78
How Stress Facilitates Phenotypic Innovation Through Epigenetic Diversity
Srikant, T., & Drost, H.-G. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2020.606800 · Cited by 67
Metadata
- Authors
- Secco, D., Wang, C., Shou, H., Schultz, M. D., Chiarenza, S., Nussaume, L., Ecker, J. R., Whelan, J., & Lister, R.
- Venue
- eLife
- Publisher
- eLife Sciences Publications, Ltd
- Published
- 2015-07-21
- Volume
- 4
- ISSN
- 2050-084X (ISSN-L)
- OpenAlex
- W2161148315
- Cited by
- 407
- References
- 5
- FWCI
- 15.44
- Type
- journal article
- Language
- en
- Open access
- gold
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- Secco, D., Wang, C., Shou, H., Schultz, M. D., Chiarenza, S., Nussaume, L., Ecker, J. R., Whelan, J., & Lister, R. (2015). Stress induced gene expression drives transient DNA methylation changes at adjacent repetitive elements. eLife. https://doi.org/10.7554/elife.09343
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