The MR-Base platform supports systematic causal inference across the human phenome

Hemani, Gibran, Zheng, Jie, Elsworth, Benjamin, Wade, Kaitlin H, Haberland, Valeriia, Baird, Denis, Laurin, Charles, Burgess, Stephen +12 more·2018·eLife

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    Liu, Yunjia, Ren, Hongyan, Zhang, Yamin, Deng, Wei, Ma, Xiaohong, Zhao, Liansheng, Li, Xiaojing, Sham, Pak, Wang, Qiang, Li, Tao · 2024 · Psychological Medicine
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    Jang, Beomjin, Kailash, BP, Tokolyi, Alex, Cuddleston, Winston H., Ravi, Ashvin, Jung, Sang-Hyuk, Naito, Tatsuhiko, Kim, Beomsu, Kim, Min Seo, Cho, Minyoung et al. · 2025
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    Kalnapenkis, Anette, Jõeloo, Maarja, Lepik, Kaido, Kukuškina, Viktorija, Kals, Mart, Alasoo, Kaur, Estonian Biobank Research Team, Metspalu, Andres, Milani, Lili, Nelis, Mari et al. · 2024 · Scientific Reports
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    Polimanti, Renato, Peterson, Roseann E., Ong, Jue-Sheng, MacGregor, Stuart, Edwards, Alexis C., Clarke, Toni-Kim, Frank, Josef, Gerring, Zachary, Gillespie, Nathan A., Lind, Penelope A. et al. · 2018
  6. Genetic evidence strongly supports managing weight and blood pressure in addition to glycemic control in preventing vascular complications in people with type 2 diabetes
    Ahmed, Altayeb, Amin, Hasnat, Drenos, Fotios, Sattar, Naveed, Yaghootkar, Hanieh · 2023 · Diabetes Care
  7. Comprehensive analysis of MAPK genes in the prognosis, immune characteristics, and drug treatment of renal clear cell carcinoma using bioinformatic analysis and Mendelian randomization
    Zheng, Xinyi, Wang, Yiqiu, Qiu, Xiaoyan · 2024 · European Journal of Pharmacology
  8. Association between psychiatric disorders and irritable bowel syndrome: A bidirectional Mendelian randomization study
    Wang, Fan, Liu, Yi-Long, Jiang, Chun-Hui, Wu, Hong-yu, Jin, Jing, Sun, Yu-Wei, He, Zi-Xuan, Kang, Le, Fang, Xue · 2025 · Journal of Affective Disorders
  9. The hidden genetic and microbial networks connecting neuropsychiatric and digestive disorders
    Xiong, Jiayi, Xu, Tiantian, Wang, Zheng, Huang, Yuanfeng, Zhang, Shiyu, Yang, Guang, Yang, Jiaqi, Gao, Shuo, Wang, Tianyang, Jian, Xingxing et al. · 2025 · Computational and Structural Biotechnology Journal
  10. Genetic proxy of lipid-lowering drugs and calcific aortic valve stenosis: A Mendelian randomization study
    Hou, Yucheng, Zhao, Jingwei, Xu, Wanchuang, Chen, Lei, Yang, Jingyue, Wang, Ziheng, Si, Ke · 2024 · Heliyon
  11. Low overlap of plasma and CSF protein quantitative trait loci affects protein discovery for neurological disease
    Western, Daniel, Yang, Chengran, Timsina, Jigyasha, Liu, Menghan, Wang, Ciyang, Campbell, Meghan C., Kotzbauer, Paul, Perlmutter, Joel S., Schindler, Suzanne E., Morris, John C. et al. · 2026 · Science Translational Medicine
  12. Multi-omics Mendelian randomisation reveals distinct molecular drivers of pathological myopia complications <i>vs</i> simple myopia
    Wang, Tong, Wang, Aoxiang, Chen, Zhongping, Lin, Xiaofeng · 2026 · Journal of Global Health
  13. MR-MAS: an end-to-end multi-agent system for autonomous Mendelian randomization analysis
    Wei, Wendi, Fan, Yuling, Li, Lin, Le, Thuc Duy, Li, Xiaomei, Cheng, Debo, Feng, Zaiwen · 2026 · Bioinformatics
  14. Plasma proteomics enhances genetic risk prediction and biological understanding of venous thromboembolism
    Mei, Yingyi, Vad, Oliver Bundgaard, Beyer, Astrid Filt, Ghouse, Jonas, Lundegaard, Pia Rengtved · 2026 · Molecular &amp; Cellular Proteomics