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SPONGIFORM ENCEPHALOPATHY OF ROCKY MOUNTAIN ELK
Abstract
A disease with striking clinical and pathologic similarities to the spongiform encephalopathies is described in six Rocky Mountain elk (Cervus elaphus nelsoni) maintained in wildlife facilities in Colorado and Wyoming. Clinical signs included behavioral alterations and progressive weight loss over a period of weeks or months. Consistent microscopic lesions were limited to the central nervous system and characterized by widespread spongiform transformation of the neuropil, intracytoplasmic vacuoles in neuronal perikaryons, and astrocytic hypertrophy and hyperplasia.
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Citations
Cited by
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Ciechanover, A., & Kwon, Y. T. (2015) · Experimental & Molecular Medicine · doi:10.1038/emm.2014.117 · Cited by 898
SCHWARTZ, C. C., HAROLDSON, M. A., WHITE, G. C., HARRIS, R. B., CHERRY, S., KEATING, K. A., MOODY, D., & SERVHEEN, C. (2006) · Wildlife Monographs · doi:10.2193/0084-0173(2006)161[1:tsaeio]2.0.co;2 · Cited by 277
Chronic Wasting Disease and Potential Transmission to Humans
Belay, E. D., Maddox, R. A., Williams, E. S., Miller, M. W., Gambetti, P., & Schonberger, L. B. (2004) · Emerging Infectious Diseases · doi:10.3201/eid1006.031082 · Cited by 257
Self-citationLiberski, P. P., Sikorska, B., Bratosiewicz-Wasik, J., Carleton Gajdusek, D., & Brown, P. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2004.04.016 · Cited by 125
Sikorska, B., Liberski, P. P., Sobów, T., Budka, H., & Ironside, J. W. (2009) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2008.00959.x · Cited by 72
Metadata
- Authors
- WILLIAMS, E. S., & YOUNG, S.
- Venue
- Journal of Wildlife Diseases
- Publisher
- Wildlife Disease Association
- Published
- 1982-10
- Volume
- 18
- Issue
- 4
- Pages
- 465-471
- ISSN
- 0090-3558 (ISSN-L)
- OpenAlex
- W2076133781
- Cited by
- 304
- References
- 0
- FWCI
- 1.15
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: SPONGIFORM ENCEPHALOPATHY OF ROCKY MOUNTAIN ELK. https://app.cochat.ai/papers/10.7589/0090-3558-18.4.465
- The paper
- WILLIAMS, E. S., & YOUNG, S. (1982). SPONGIFORM ENCEPHALOPATHY OF ROCKY MOUNTAIN ELK. Journal of Wildlife Diseases. https://doi.org/10.7589/0090-3558-18.4.465
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
