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Cited by 112Virus-based gene therapy researchImmunotherapy and Immune ResponsesPoxvirus research and outbreaks

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Viral vectors for vaccine applications

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Choi, Youngjoo, Chang, Jun·2013·Clinical and Experimental Vaccine Research
DOI 10.7774/cevr.2013.2.2.97PMC PMC3710930
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Abstract

Traditional approach of inactivated or live-attenuated vaccine immunization has resulted in impressive success in the reduction and control of infectious disease outbreaks. However, many pathogens remain less amenable to deal with the traditional vaccine strategies, and more appropriate vaccine strategy is in need. Recent discoveries that led to increased understanding of viral molecular biology and genetics has rendered the used of viruses as vaccine platforms and as potential anti-cancer agents. Due to their ability to effectively induce both humoral and cell-mediated immune responses, viral vectors are deemed as an attractive alternative to the traditional platforms to deliver vaccine antigens as well as to specifically target and kill tumor cells. With potential targets ranging from cancers to a vast number of infectious diseases, the benefits resulting from successful application of viral vectors to prevent and treat human diseases can be immense.

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Cited by

Metadata

Authors
Choi, Y., & Chang, J.
Affiliations
Ewha Womans University (KR)
Corresponding author
Chang, Jun
ORCID
Venue
Clinical and Experimental Vaccine Research
Publisher
XMLink
Published
2013
Volume
2
Issue
2
Pages
97
ISSN
  • 2287-3651 (ISSN-L)
  • 2287-366X
DOI
10.7774/cevr.2013.2.2.97
PMC
PMC3710930
OpenAlex
W2120183880
Cited by
112
References
0
Citations by year
2026: 2 · 2025: 8 · 2024: 8 · 2023: 10 · 2022: 15 · 2021: 16 · 2020: 17 · 2019: 5 · 2018: 4 · 2017: 6 · 2016: 10 · 2015: 6 · 2014: 3 · 2013: 2
FWCI
4.64
Type
journal article
Language
en
Open access
Licence
  • cc-by-nc
  • creativecommons.org/licenses/by-nc/3.0/ (tdm)
Locations
  • Clinical and Experimental Vaccine Research (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
Funders
Ministry of Education, Science and Technology
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Virus-based gene therapy research
  • Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
  • Life Sciences › Immunology and Microbiology › Virology › Poxvirus research and outbreaks
Keywords
viral vectors, vaccine platforms, vaccine antigens, cancer vaccines, tumor cell targeting, humoral immune response, cell-mediated immunity, infectious disease vaccines, inactivated vaccine, live attenuated vaccine

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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