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Skeletal muscle sonography: a correlative study of echogenicity and morphology
Abstract
In skeletal muscle sonography high echogenicities have proved to be of diagnostic value. The following study examines whether these echointensities are caused mainly by interstitial fat or fibrosis. Consequently, the echogenicities of 86 muscles, their diameters, and the thickness of subcutaneous fat layers superficial to these muscles were measured and compared for content of fat and connective tissue, which were assessed by morphometry and biochemical testing in the corresponding muscle biopsy samples. The results indicate that fat replacement constitutes the main cause of increased muscle echogenicity, whereas intramuscular fibrosis did not significantly affect the muscles' echogenicity.
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“The degree of echogenicity also appears to differ based on the bioenergetics of the muscle and its location (Reimers et al., 1993).”
From Myosteatosis in the Context of Skeletal Muscle Function Deficit: An Interdisciplinary Workshop at the National Institute on Aging (2020) · cites this paper as Reimers et al., 1993
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“Muscle echo intensity is an index of intramuscular adipose and fi brosis tissue ( 19 , 31 ).”
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“16,17 The importance of evaluating the quality of IntraMAT, in patients, in addition to muscle quantity (i.e., cross-sectional area, CSA), has been increasingly recognized.”
Neue Methode zur portablen Muskelanalyse mittels Ultraschall
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“Increased muscle echogenicity has been associated with structural alterations such as intra-muscular fat infiltration, connective tissue proliferation, and fibrosis, indicating qualitative changes in muscle composition rather than quantitative changes in muscle mass [36–38].”
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“This may be particularly challenging in paretic muscle, where potentially increased fat and fibrotic tissue could alter ultrasound image quality and contrast (Pillen et al., 2008; Pillen et al., 2009; Reimers et al., 1993).”
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Metadata
- Authors
- Reimers, K., Reimers, C. D., Wagner, S., Paetzke, I., & Pongratz, D. E.
- Affiliations
- Ludwig-Maximilians-Universität München (DE)
- Venue
- Journal of Ultrasound in Medicine
- Publisher
- Wiley
- Published
- 1993-02
- Volume
- 12
- Issue
- 2
- Pages
- 73-77
- ISSN
- 0278-4297 (ISSN-L)
- OpenAlex
- W2228483624
- Cited by
- 385
- References
- 2
- Citations by year
- 2026: 6 · 2025: 16 · 2024: 26 · 2023: 21 · 2022: 39 · 2021: 42 · 2020: 32 · 2019: 32 · 2018: 35 · 2017: 16 · 2016: 16 · 2015: 23 · 2014: 14 · 2013: 5 · 2012: 9
- FWCI
- 0.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Ultrasound in Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Ultrasound Imaging and Elastography
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Ultrasound in Clinical Applications
- Keywords
- muscle echogenicity, intramuscular fat, muscle morphology, subcutaneous fat thickness, muscle biopsy, fat replacement, connective tissue
- MeSH terms
- Adipose Tissue, Adolescent, Adult, Aged, Biopsy, Child, Female, Humans, Male, Middle Aged, Muscles, Neuromuscular Diseases, Ultrasonography
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