Cited by 7Essential Oils and Antimicrobial ActivityMedicinal Plant ResearchEthnobotanical and Medicinal Plants Studies

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Evaluation of in Vitro Antibacterial Activity of Caralluma umbellata Haw Used in Traditional Medicine by Indian Tribes

Open access
Babu, K.·2014·Annual Research & Review in Biology

Abstract

Aims: To find out a scientific validation for the traditional knowledge of tribals of Chittoor District, India for their usage of Caralluma umbellata Haw to cure stomach disorder and pain.Methodology: Antibacterial activity of Caralluma umbellata Haw was studied on a few Gram positive and Gram negative bacteria.The dry roots and stems were extracted using hexane, benzene, diethyl ether, chloroform, acetone and methanol and were tested for their antibacterial activity. Results:The root extracts were found to be effective against most of the organisms than the stem extracts.The extracts were highly effective against Bacillus subtillis, Bacillus cereus, Escherichia coli and Staphylococcus aureus.Chloroform extracts of both roots and stems exhibited good antibacterial activity against Gram positive and Gram negative bacteria except Pseudomonas aeruginosa.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.9734/arrb/2014/6401

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Earlier studies have illustrated Caralluma plants' antidiabetic, anti-inflammatory, anti-nociceptive, antiulcerogenic, anti-oxidant and hepatoprotective activities.

    “Earlier studies have illustrated their antidiabetic, anti-inflammatory, anti-nociceptive, antiulcerogenic anti-oxidant and hepatoprotective activities. 12”

    From Caralluma umbellata Haw. protects liver against paracetamol toxicity and inhibits CYP2E1 (2017) · cites this paper as [12]

    Section 1.2 lists anti-inflammatory, antiulcer, antinociceptive, antioxidant, and antihyperglycemic properties of Caralluma, broadly supporting five of the six activities claimed. It does not mention hepatoprotective activity. No page number is available in our copy. (LLM, conf=0.89)

    Experimental — accuracy not yet measured
  • Traditionally Caralluma umbellata has been used to relieve stomach disorders and abdominal pains.

    “Traditionally this plant has been used to relieve stomach disorders and abdominal pains. 12”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 76

  1. Hartmann T. The lost origin of chemical ecology in the late 19th century. Proc Natl Acad Sci. USA. 2008;105(12):4541-6.
  2. Bruneton Jean. Pharmacognosy, Phytochemistry, Medicinal plants. 2 nd edition. France Lavoisier publishing; 1999.
  3. Patel NB, Patel KC. Molecular Docking Study On Anisomeles Indica Linn. Wild Ethnomedicinal Plant for Therapeutic Purpose. Life Sci Leaflets. 2012;11:33-9.
  4. Ramesh MY, Appa Rao AVN, Prabhakar MC, Murlidhar N, Seshagiri Rao C, Madhava Reddy B. Antinociceptive and anti-inflammatory activity of a flavonoid isolated from Caralluma attenuata. J Ethnopharmcol. 1998;62:63-6.
  5. Atal CK, Sharma BM, Bhatia AK. Search of emergency foods through wild flora of Jamu and Kashmir state. Sunderbani area-1. The Indian Forester. 1980;106:211-19.
  6. Qiu SY, Lin LZ, Cordell GA, Ramesh M, Ravi Kumar B, Radhakrishna M, et al. Acylated C-21 steroidal Bisdesmosidic glycosides from Caralluma umbellata. Phytochem. 1997;46:333-40.
  7. Zakaria MNM, Islam MW, Radhakrishnan R, et al. Antinociceptive and anti- inflammatory properties of Caralluma arabica. J Ethnopharmacol. 2001;76:155-8.
  8. AL-Yaha MA, Abdel-Sattar E. Pregnane Glycoside from Caralluma russeliana. J Nat Pro Chemical constitue. 2000;63(45):1451-53.
  9. Stewart RR, Eds Nasir E, Ali S. Annolated Catalogue of Vascular Plants of West Pakistan and Kashmir; Fakhri Print Press, Karachi; 1972.
  10. Zakaria MNM, Islam MW, Radhakrishnan, et al. Antigastric ulcer and cytoprotective properties of Caralluma arabica. Pharm Biol. 2002;40:225-30.
  11. Abdel-Sattar E, Ahmed AA, Hegazy MEF, Farag MA, Al-Yahya MA. Acylated pregnane glycosides from Caralluma russeliana. Phytochem. 2007;68:1459-63.
  12. Tatiya AU, Kulkarni AS, Surana SJ, Bari ND. Anti oxidant and hypoglycemic effect of Caralluma adscendens Roxb. in Alloxanized diabetic rats. Int J Pharmacol. 2010;6(4):362-68.
  13. Venktesh S, Reddy GD, Reddy BM, Ramesh M. Appa Rao AVN. Anti hyper glycemic activity of Caralluma attenuate. Fitotherapia. 2003;74:274-79.
  14. Khan SW, Khatoon S. Ethnobotanical Studies on some Useful Herbs of Haramosh and Bugrote Valleys in Gilgit. Northern Areas of Pakistan. Pak J Bot. 2008;40:43-58.
  15. Bader A, Braca A, De Tommasi N, Morelli I. Further constituents from Caralluma negevensis. Phytochem. 2003;62:1277-81.
  16. Qiu SY, Cordell GA, Ravi Kumar B, Nageswara Rao Y, Ramesh M, Kokate C, et al. Bisdesmosidic Pregnane glycosides from Caralluma Lasiantha. Phytochem. 1999;50:485-91.
  17. Ray S, Nagaiah K, Khan NF. Anti-inflammatory activity of Carumbelloside-III, isolated from Caralluma umbellata. NSHM J Pham Health Mgt. 2011;2:83-8.
  18. Sawant BM, Sayad TD. n-Pentatriacontane from Caralluma fimbriata. J Shivaji Univ Sci. 1978;18:87-91.
  19. Vedavathy S, Mridula V, Sudhakar A. Tribal Medicine of Chittoor District of Andhra Pradesh, India, I edition, Herbal Folklore Research Centre; Tirupati; 1997.
  20. Pullaiah T. Encyclopedia of world medicinal plants. Regency Publications New Delhi India. 2006;2:437-9.
  21. Basavaraju R, Vennel Raj J, Bhiravamurthy PV, Medicinal Plant Resources of Puttaparthi Mandal, Taxonomic Overview and Need for Conservation. Ethnobotanical Leaflets. 2009;13:1382-1400.
  22. Vogel AI, A Text Book of Practical Organic Chemistry. 3 rd edition. London ELBS. 1971;46.
  23. Trease and Evans Pharmacognosy. 15 th edition. U.K. W.B. Company. 2002;135.
  24. Jefrey B. Harborne. Phytochemical Methods -A Guide to Modern Techniques of Plant Analysis. 3 rd edition. London. Chapman & Hall. 1998;129.
  25. Krishnaswamy NR. Chemistry of Natural Products: A Laboratory Handbook. 1 st Edition. Hyderabad. Universities Press,India, Private Limited. 2003;48.
  26. Marchese A, Shito GC. Resistance pattern of lower respiratory tract pathogens of Europe. Int J Antimicrobl Agent. 2001;16:25-29.
  27. Aliero AA, Afolayan AJ. Antimicrobial activity of Solanum tomentosum. African J Biotech. 2006;5(4):369-2.
  28. John D. One hundred useful raw drugs of the Kani tribes of Trivandrum forest division, Kerala. Int J Crude Drug Res. 1984;22:17-39.
  29. Adoum OA, Akinniyi JA, Omar T. The effect of geographical location on the antimicrobial activities and trace element concentrations in the root of Calotropis procera (Ait.) R. Br, Annals of Borno. 1997;13(14):199-207.
  30. Odugbemi T. A textbook of medicinal plants from Nigeria. University of Lagos Press. Nigeria. 2008;20-323.
  31. Marjorie MC. Plants products as antimicrobial agents. Clin Microbial Rev. 1999;12:564-82.
  32. Kawo AH, Water purification potentials and in-vivo toxicity evaluation of the aqueous and petroleum-ether extracts of Calotropis procera (Ait.F.) Ait.F. latex and Moringa oleifera LAM seed powder. PhD thesis. Microbiology Unit, Department of Biological Sciences, Bayero University, Kano, Nigeria. 2007;184.
  33. Kawo AH, Mustapha A, Abdullahi BA, Rogo LD, Gaiya ZA, Kumurya AS. Phytochemical properties and antibacterial activities of the leaf and latex extracts of Calotropis procera (Ait.F.). Bayero. J Pure Appl Sci. 2009;2(1):34-40.
  34. Yusha'u M, Bukar A, Balarabe AI. Prevalence and sensitivity of enterobacterial isolates from patients with urinary tracts infections to Acalypha wilkisenia extracts. Biol Environ Sci J Trop. 2008;5(3):72-76.
  35. Lin LJ, Lin LZ, Gil RR, Cordell GA, Ramesh MB, Appa Rao AVN. Pregnane glycoside from C. umbellate Phytochem. 1994;35(6):1549-53.
  36. Ramesh M, Nageswara Rao Y, Rama Kumar M, Krishna Mohan G, Ravi Kumar B, Appa Rao AVN, et al. Flavone glycosides from three Caralluma species. Bioche Syst Eco. 1999;27:85-86.
  37. Ramesh M, Nageshwar Rao Y, Kumar MR, Venkata Narasimha Appa Rao A, Prabhakar MC, Reddy BM. Antinociceptive and anti-inflammatory activity of carumbelloside-I isolated from Caralluma umbellata. J Ethnopharmacol. 1999b;68:349-52.
  38. Ramesh M, Ravi Kumar B, Chandra K, Venkatesdh S, Appa Rao AVN. C21 Pregnane Steroid from Caralluma umbellata. Nat Prod Sci. 2005;11(2):115-17.
  39. Krishna Mohan G, Reddy BM, Nageswara Rao Y, Srinivas B, Sunil Thomas N, Appa Rao AVN. Acylated C-21 steroidal bisdesmosidic glycosides from Caralluma umbellata. Phytochem. 1997;46(2):333-340.
  40. Suresh Babu K, Subba Rao R, Radhakrishnan Sriveda VV, Madhusudana Rao J, Siva Rambabu S, A new pregnane steroid from the stems of Caralluma umbellata', J Asian Nat Prod Res. 2008;10(11):1013 -16.
  41. Madhuri V, Amrutha VA, Murthy KSR. Evaluation of Immuno stimulating Activities of Caralluma spp. Int J Pharmacognosy and Phytochem Res. 2010;2(4):1-4.
  42. Bennett R. The 'Direct Costs' of Livestock Disease: The Development of a System of Models for the Analysis of 30 Endemic Livestock Diseases in Great Britain. J Agri Eco. 2003;54(1):55-71.
  43. Peter Josling. Stabilised Allicin, Power, Performance, Proof. 1 st edition. HRC Publications, 2010.
  44. Kulkarni A, Mute Vaishali SM, Dhamane Suchita P, Gadekar AS. Evaluation of Antibacterial Activity of Caralluma adscendens RoxbStem. Int Res J Pharm. 2012;3(9):269-70.
  45. Kamil MA, Fjayaraj F, Ahmad C, Gunasekhar S. Samuel Chan K, et al. Identification and quantification of flavonoids from Caralluma arabica and its quality control studies. J Pharm Pharmacol. 1999;51:225-9.
  46. Dewick PM. Medicinal Natural Products -A Biosynthetic approach. Wiley, New-York, 2001.
  47. Andrzej LD, Wianowska D, Barbara. The antioxidant properties of alcoholic extracts from Sambucus nigra L. LWT-Food Sci Technol. 2006;39(3):308-15
  48. Tanaka O, Tamura Y, Masuda H, Mizutani K. Application of saponins in food and cosmetics. Saponins of Mohave yucca and Sapindus mukurossi In Waller, GR, Yamasaki, K eds., Saponins used in food and Agricultural, Plenum Press, New York. 1996;1-11.
  49. Ali Y, Ahmet M, Ayse AK, Antioxidant and antimicrobial activities of Polygonum cognatum Meissn extracts. J Sci Food Agric. 2000;83:64-69.
  50. Gronhaug TE, Glaeserud S, Skogsrud M, Ballo N, Bah S, Diallo D, Paulsen BS. Ethnopharmacological survey of six medicinal plants from Mali, West Afr J Ethnobiol Ethnomed. 2008;4(26):1186-1746.
  51. Kumar A, IIavarasan R, Jayachandran T, Decaraman M, Aravindhan P, Padmanabhan N, Krishman MRV. Phytochemicals investigation on a tropical plant, Syzgium cumini from Kattuppalayam, Erode District. Tamil Nadu, South India. Pak J Nutr. 2009;8(1):83-85.
  52. Osbourn A. Saponins and plant defense -a soap story. Trends in Plant Sci. 1996;1:4- 9.
  53. Osbourn A, Saponins in cereals. Phytochem. 2003;62:1-4.
  54. Harish H, Ravikumar A, Ramkrishana R. Phytochemical and antibacterial properties of Calotropis igantea, Int J Pharmacol Bio Sci. 2007;1(1):75-7
  55. Naik JB, Jadge DR. Anti-bacterial and anti-fungal activity of Actiniopteris radiata and Caralluma adscendens. Int J PharmTech Res. 2010;2(3):1751-53.
  56. Bauer AW, Kirby WM, Sherris JC, Turck M. Antibiotic susceptibility testing by a standardized single disc method. Am J Clin Pathol. 1966;45(4): 493-6
  57. Tava A, Avato P. Chemistry and biological activity of triterpene saponins from Medicago species. Nat Prod Commun. 2006;1:1159-80.
  58. Fieser LF, Fieser M. "Reagents for Organic Synthesis" (Translated into Russian), Izd.Mir, Moscow. 1971;5:107.
  59. Gibbons GF, Mitropoulos KA, Myant NB. Biochemistry of Cholesterol. Elsevier, New York,1982;63.
  60. Geissman TA. Flavonoid compounds, tannins, lignins and related compounds. In: Florkin M, Stotz EH (eds). Pyrrole Pigments, Isoprenoid Compounds and Phenolic Plant Constituents, New York: Elsevier. 1963;9:2653.
  61. Dixon RA, Dey PM. Lamb CJ. Phytoalexins: enzymology and molecular biology. Adv Enzymol. 1983;55:1-69.
  62. Cowan MM, Plant products as antimicrobial agents. Clin Microbiol Rev. 1999;12:564- 582.
  63. Scalbert A. Antimicrobial properties of tannins. Phytochem. 1991;30:3875-83.
  64. Tharan NT, Vaidvu R, Palanisamy M, Justin V. Antibacterial activity of Evolvulus alsinoides, Indian Drugs. 2003;40(10):585-86.
  65. Tsuchiya H, Sato M, Miyazaki T, Fujiwara S, Tanigaki S, Ohyama M, et al. Comparative study on the antibacterial activity of phytochemical flavonones against methicillin-resistant Staphylococcus aureus. J Ethnopharmacol. 1996;50:27-34.
  66. Chaurasia SC, Vyas KK. In vitro effect of some volatile oil against Phytophtora parasitica var. piperina. J Res Indian Med Yoga Homeopath. 1997;1:24-6.
  67. Miura YH, Tomita I, Watanabe T, Hirayama T, Fukui S .Active oxygen generation by flavonoids. Biol Pharm Bull. 1998;21:93-96.
  68. Delehanty JB, Johnson BJ, Hickey TE, Pons T, Ligler FS. Plant Proanthocyanidins Bind to and Neutralize Bacterial Lipopolysaccharides. Nrl Review. 2008;101-07.
  69. Matsui T, Tanaka T, Amura S, Toshima A, Miyata Y, Tanaka K, et al. Alpha- glucosidase inhibitory profile of catechins and the aflavins. J Agri Food Chem. 2007;55:99-105.
  70. Ikigai HT, Nakae Hara Y, Shimamura T. Bactericidal catechins damage the lipid bilayer. Biochim Biophys Acta. 1993;1147:132-36.
  71. Toda MS, Okubo Hiyoshi R, Shimamura T. The bactericidal activity of tea and coffee. Lett Appl Microbiol. 1989;8:123-5.
  72. Naz S, Siddiqi R, Ahmad S. Rasool S, Sayeed S. Antibacterial activity directed isolation of compounds from Punica granatum. J Food Sci. 2007;72:341-45.
  73. Fan W, Chi Y, Zhang S. The use of a tea poly phenol dips to extend the shelf life of silver carp during storage of ice. Food Chem. 2008;108:148-53.
  74. David Newman J, Natural Products as Leads to Potential Drugs: An Old Process or the New Hope for Drug Discovery. J Med Chem. 2008;51:2589-99.
  75. Winter J, Lillian H, Moore VR, Dowell JR, Bokkenheuser VD. C-ring cleavage of flavonoids by human intestinal bacteria. Appl Environ Microbiol. 1989;55:1203-8.
  76. Ravikumar S, Syed Ali M, Ramu A, Ferosekhan M. Antibacterial Activity of Chosen Mangrove Plants Against Bacterial Specified Pathogens, World Appl Sci J. 2011;14(8):1198-1202.

Cited by

Sorted by citations

Metadata

Authors
Babu, K.
Corresponding author
Babu, K.
Venue
Annual Research & Review in Biology
Published
2014-01-10
Volume
4
Issue
6
Pages
840-855
ISSN
2347-565X (ISSN-L)
OpenAlex
W2316188700
Cited by
7
References
1
Citations by year
2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 1 · 2018: 1 · 2017: 1
FWCI
0.36
Type
journal article
Language
en
Open access
Locations
  • Annual Research & Review in Biology (publishedVersion)
  • Annual Research & Review in Biology (publishedVersion, cc-by)
  • viXra (submittedVersion)
  • HAL (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Ethnobotanical and Medicinal Plants Studies
Keywords
antibacterial activity, traditional medicine, tribal knowledge, plant extracts, root and stem extracts, Gram-positive bacteria, Gram-negative bacteria, Escherichia coli, Staphylococcus aureus, Bacillus cereus, Bacillus subtilis, Pseudomonas aeruginosa, Chittoor district

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review