Factor affecting photo and thermal stability of levothyroxine sodium
Open accessAbstract
Journal of Pharmaceutical Research International (ISSN: 2456-9119) is dedicated to publish high quality papers in all areas of pharmaceutical Science including pharmaceutical drugs, community pharmacy, hospital pharmacy, clinical pharmacy, compounding pharmacy, consultant pharmacy, internet pharmacy, veterinary pharmacy, nuclear pharmacy, military pharmacy, pharmacy informatics, pharmaceutics, medicinal chemistry, pharmacognosy, pharmacotherapy, pharmacodynamics, pharmacokinetics, clinical pharmacology, neuropharmacology, psychopharmacology, pharmacogenetics, pharmacogenomics, pharmacoepidemiology, toxicology, theoretical pharmacology, posology, pharmacognosy, behavioral pharmacology, environmental pharmacology, medicine development and safety testing, drug legislation and safety, pharmaceutical microbiology, pharmaceutical molecular biology, pharmaceutical biotechnology. The journal also encourages the submission of useful reports of negative results. This is a quality controlled, OPEN peer reviewed, open access INTERNATIONAL journal.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Exposure to sunlight, high temperatures, humidity, and oxygen significantly accelerates the degradation of LT4 tablets.
“Exposure to sunlight, high temperatures, humidity, and oxygen significantly accelerates the degradation of LT4 tablets (121, 122).”
From Levothyroxine: conventional and novel drug delivery formulations. (2023) · cites this paper as [121]
Exposure to direct sunlight for 80 minutes results in more than 60% decomposition of LT4.
“Exposure to direct sunlight for 80 minutes results in more than 60% decomposition (121).”
From Levothyroxine: conventional and novel drug delivery formulations. (2023) · cites this paper as [121]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Practical Pharmaceutical Chemistry
(1941) · Nature · doi:10.1038/147559c0 · Cited by 701 · see citing works
Flagged first, then by citations
Research works printed but not linked: 6
- World Health Organization. Quality assurance. Quality assurance of Pharmaceutical. 2007;2:16.
- Moffat Anthony C, Osselton M David, Brian Widdop, Laurent Y Galichet. Clarke's Analysis of Drugs and Poisons third edition; 2006.
- Gregory W. Roberts, Clinical Pharmacist, Repatriation General Hospital, Daw Park, South Australia, Taking care of thyroxine, Aust Prescr. 2004;27:75-6.
- Brower JF, Toler DY, Reepmeyer JC. J. of pharm. Sc. 1984;73:1315-17.
- Won C. kinetics of degradation of levothyroxine in aqueous solution and in solid state. J. of Pharmaceutical Research. 1992; 9(1):131-7.
- Federal Register, (August 14, 1997). 62(157):43535-4358.
Cited by
Sorted by citations
Levothyroxine: conventional and novel drug delivery formulations.
Liu, H., Li, W., Zhang, W., Sun, S., & Chen, C. (2023) · Endocrine Reviews · doi:10.1210/endrev/bnac030 · Cited by 63 · see citing works
Ledeți, I., Romanescu, M., Cîrcioban, D., Ledeți, A., Vlase, G., Vlase, T., Suciu, O., Murariu, M., Olariu, S., Matusz, P., et al. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12010058 · Cited by 23 · see citing works
Levothyroxine sodium pentahydrate tablets – formulation considerations
Kaur, N., & Suryanarayanan, R. (2021) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2021.08.006 · Cited by 19 · see citing works
- Authors
- Abdallah, S., & Mohamed, I.
- Venue
- British Journal of Pharmaceutical Research
- Publisher
- Sciencedomain International
- Published
- 2016-01-10
- Volume
- 10
- Issue
- 2
- Pages
- 1-11
- ISSN
- 2231-2919 (ISSN-L)
- OpenAlex
- W2995725108
- Cited by
- 7
- References
- 1
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2018: 2
- FWCI
- 0.53
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Journal of Pharmaceutical Research International (publishedVersion)
- HAL (submittedVersion)
- Topics
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical Methods in Pharmaceuticals
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pharmaceutical Quality and Counterfeiting
- Keywords
- levothyroxine sodium, photostability, thermal stability, drug degradation, stability coefficient, thyroid hormones
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
