Johnson, Randall S.

TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens

Peyssonnaux, C., Zinkernagel, A. S., Datta, V., Lauth, X., Johnson, R. S., & Nizet, V. (2006) · Blood

Iron Metabolism and DisordersImmune Response and Inflammation

Cited by 379

Hypoxia-Inducible Factor-1α Is a Key Regulator of Metastasis in a Transgenic Model of Cancer Initiation and Progression

Liao, D., Corle, C., Seagroves, T. N., & Johnson, R. S. (2007) · Cancer Research

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 339

The hypoxia-inducible factor-1α is a negative factor for tumor therapy

Unruh, A., Ressel, A., Mohamed, H. G., Johnson, R. S., Nadrowitz, R., Richter, E., Katschinski, D. M., & Wenger, R. H. (2003) · Oncogene

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 334

Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia

Fang, H.-Y., Hughes, R., Murdoch, C., Coffelt, S. B., Biswas, S. K., Harris, A. L., Johnson, R. S., Imityaz, H. Z., Simon, M. C., Fredlund, E., et al. (2009) · Blood

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 319

Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging

Ho, Y.-H., del Toro, R., Rivera-Torres, J., Rak, J., Korn, C., García-García, A., Macías, D., González-Gómez, C., del Monte, A., Wittner, M., et al. (2019) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 315

Cellular Transformation and Malignancy Induced by ras Require c-jun

Johnson, R., Spiegelman, B., Hanahan, D., & Wisdom, R. (1996) · Molecular and Cellular Biology

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 282

Hypoxia inducible factor (HIF) function in innate immunity and infection

Zinkernagel, A. S., Johnson, R. S., & Nizet, V. (2007) · Journal of Molecular Medicine

Cancer, Hypoxia, and MetabolismImmune cells in cancer

Cited by 265

c-Jun Is Essential for Organization of the Epidermal Leading Edge

Li, G., Gustafson-Brown, C., Hanks, S. K., Nason, K., Arbeit, J. M., Pogliano, K., Wisdom, R. M., & Johnson, R. S. (2003) · Developmental Cell

Wound Healing and TreatmentsSkin and Cellular Biology Research

Cited by 224

Role of the hypoxia inducible factors HIF in iron metabolism

Peyssonnaux, C., Nizet, V., & Johnson, R. S. (2008) · Cell Cycle

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 217

Cytotoxic T-cells mediate exercise-induced reductions in tumor growth

Rundqvist, H., Veliça, P., Barbieri, L., Gameiro, P. A., Bargiela, D., Gojkovic, M., Mijwel, S., Reitzner, S. M., Wulliman, D., Ahlstedt, E., et al. (2020) · eLife

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 216

Loss of Skeletal Muscle HIF-1α Results in Altered Exercise Endurance

Mason, S. D., Howlett, R. A., Kim, M. J., Olfert, I. M., Hogan, M. C., McNulty, W., Hickey, R. P., Wagner, P. D., Kahn, C. R., Giordano, F. J., et al. (2004) · PLoS Biology

Cardiovascular and exercise physiologyMuscle Physiology and Disorders

Cited by 210

Cantuzumab Mertansine, a Maytansinoid Immunoconjugate Directed to the CanAg Antigen: A Phase I, Pharmacokinetic, and Biologic Correlative Study

Tolcher, A. W., Ochoa, L., Hammond, L. A., Patnaik, A., Edwards, T., Takimoto, C., Smith, L., de Bono, J., Schwartz, G., Mays, T., et al. (2003) · Journal of Clinical Oncology

Monoclonal and Polyclonal Antibodies ResearchToxin Mechanisms and Immunotoxins

Cited by 206

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice

Walmsley, S. R., Chilvers, E. R., Thompson, A. A., Vaughan, K., Marriott, H. M., Parker, L. C., Shaw, G., Parmar, S., Schneider, M., Sabroe, I., et al. (2011) · Journal of Clinical Investigation

Cell death mechanisms and regulationNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 191

Role of HIF‐1α in skeletal development

Wan, C., Shao, J., Gilbert, S. R., Riddle, R. C., Long, F., Johnson, R. S., Schipani, E., & Clemens, T. L. (2010) · Annals of the New York Academy of Sciences

Bone Metabolism and DiseasesBone Tissue Engineering Materials

Cited by 173

Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success

Branco-Price, C., Zhang, N., Schnelle, M., Evans, C., Katschinski, D. M., Liao, D., Ellies, L., & Johnson, R. S. (2012) · Cancer Cell

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 168

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia

Koh, H. S., Chang, C. Y., Jeon, S.-B., Yoon, H. J., Ahn, Y.-H., Kim, H.-S., Kim, I.-H., Jeon, S. H., Johnson, R. S., & Park, E. J. (2015) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 141

Hypoxia inducible factor 1α regulates T cell receptor signal transduction

Neumann, A. K., Yang, J., Biju, M. P., Joseph, S. K., Johnson, R. S., Haase, V. H., Freedman, B. D., & Turka, L. A. (2005) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismT-cell and B-cell Immunology

Cited by 120

A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection

Okumura, C. Y. M., Hollands, A., Tran, D. N., Olson, J., Dahesh, S., von Köckritz-Blickwede, M., Thienphrapa, W., Corle, C., Jeung, S. N., Kotsakis, A., et al. (2012) · Journal of Molecular Medicine

Cancer, Hypoxia, and MetabolismAntimicrobial Resistance in Staphylococcus

Cited by 115

Influence of hypoxia-inducible factor 1α on dendritic cell differentiation and migration

Köhler, T., Reizis, B., Johnson, R. S., Weighardt, H., & Förster, I. (2012) · European Journal of Immunology

Immunotherapy and Immune ResponsesCancer, Hypoxia, and Metabolism

Cited by 108

The response of c-Jun/AP-1 to chronic hypoxia is hypoxia-inducible factor 1α dependent

Laderoute, K. R., Calaoagan, J. M., Gustafson-Brown, C., Knapp, A. M., Li, G.-C., Mendonca, H. L., Ryan, H. E., Wang, Z., & Johnson, R. S. (2002) · Molecular and Cellular Biology

Cancer, Hypoxia, and MetabolismKruppel-like factors research

Cited by 105

Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells

Hong, J., Tobin, N. P., Rundqvist, H., Li, T., Lavergne, M., García-Ibáñez, Y., Qin, H., Paulsson, J., Zeitelhofer, M., Adzemovic, M. Z., et al. (2015) · Journal of the National Cancer Institute

Immune cells in cancerAngiogenesis and VEGF in Cancer

Cited by 75

HIF-2α is essential for carotid body development and function

Macias, D., Cowburn, A. S., Torres-Torrelo, H., Ortega-Sáenz, P., López-Barneo, J., & Johnson, R. S. (2018) · eLife

Neuroscience of respiration and sleepCancer, Hypoxia, and Metabolism

Cited by 59

Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart

Ashmore, T., Fernandez, B. O., Branco‐Price, C., West, J. A., Cowburn, A. S., Heather, L. C., Griffin, J. L., Johnson, R. S., Feelisch, M., & Murray, A. J. (2014) · The Journal of Physiology

Nitric Oxide and Endothelin EffectsHigh Altitude and Hypoxia

Cited by 58

Modified Hypoxia-Inducible Factor Expression in CD8+ T Cells Increases Antitumor Efficacy

Veliça, P., Cunha, P. P., Vojnovic, N., Foskolou, I. P., Bargiela, D., Gojkovic, M., Rundqvist, H., & Johnson, R. S. (2021) · Cancer Immunology Research

Cancer, Hypoxia, and MetabolismImmunotherapy and Immune Responses

Cited by 52