McVean, Gil

The UK Biobank resource with deep phenotyping and genomic data

Bycroft, C., Freeman, C., Petkova, D., Band, G., Elliott, L. T., Sharp, K., Motyer, A., Vukcevic, D., Delaneau, O., O’Connell, J., et al. (2018) · Nature

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 8,876

A new multipoint method for genome-wide association studies by imputation of genotypes

Marchini, J., Howie, B., Myers, S., McVean, G., & Donnelly, P. (2007) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,609

Mapping copy number variation by population-scale genome sequencing

1000 Genomes Project, Mills, R. E., Walter, K., Stewart, C., Handsaker, R. E., Chen, K., Alkan, C., Abyzov, A., Yoon, S. C., Ye, K., et al. (2011) · Nature

Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms

Cited by 1,140

A Fine-Scale Map of Recombination Rates and Hotspots Across the Human Genome

Myers, S., Bottolo, L., Freeman, C., McVean, G., & Donnelly, P. (2005) · Science

Genetic Associations and EpidemiologyChromosomal and Genetic Variations

Cited by 1,134

A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC

de Bakker, P. I. W., McVean, G., Sabeti, P. C., Miretti, M. M., Green, T., Marchini, J., Ke, X., Monsuur, A. J., Whittaker, P., Delgado, M., et al. (2006) · Nature Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 766

A Coalescent-Based Method for Detecting and Estimating Recombination From Gene Sequences

McVean, G., Awadalla, P., & Fearnhead, P. (2002) · Genetics

Evolution and Genetic DynamicsGenetic diversity and population structure

Cited by 708

Drive Against Hotspot Motifs in Primates Implicates the PRDM9 Gene in Meiotic Recombination

Myers, S., Bowden, R., Tumian, A., Bontrop, R. E., Freeman, C., MacFie, T. S., McVean, G., & Donnelly, P. (2010) · Science

Chromosomal and Genetic VariationsGenomics and Chromatin Dynamics

Cited by 683

Differential confounding of rare and common variants in spatially structured populations

Mathieson, I., & McVean, G. (2012) · Nature Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 385

Inferring whole-genome histories in large population datasets

Kelleher, J., Wong, Y., Wohns, A. W., Fadil, C., Albers, P. K., & McVean, G. (2019) · Nature Genetics

Forensic and Genetic ResearchGenetic diversity and population structure

Cited by 313

UK Biobank release and systematic evaluation of optimised polygenic risk scores for 53 diseases and quantitative traits

Thompson, D. J., Wells, D., Selzam, S., Peneva, I., Moore, R., Sharp, K., Tarran, W. A., Beard, E. J., Riveros-Mckay, F., Giner-Delgado, C., et al. (2022) · medRxiv

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 280

Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity

Dendrou, C. A., Cortes, A., Shipman, L., Evans, H. G., Attfield, K. E., Jostins, L., Barber, T., Kaur, G., Kuttikkatte, S. B., Leach, O. A., et al. (2016) · Science Translational Medicine

Genetic Associations and EpidemiologyRheumatoid Arthritis Research and Therapies

Cited by 264

A Statistical Method for Predicting Classical HLA Alleles from SNP Data

Leslie, S., Donnelly, P., & McVean, G. (2008) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 173

Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants

Panoutsopoulou, K., Hatzikotoulas, K., Xifara, D. K., Colonna, V., Farmaki, A.-E., Ritchie, G. R. S., Southam, L., Gilly, A., Tachmazidou, I., Fatumo, S., et al. (2014) · Nature Communications

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 70

A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability

Davies, B., Brown, L. A., Cais, O., Watson, J., Clayton, A. J., Chang, V. T., Biggs, D., Preece, C., Hernandez-Pliego, P., Krohn, J., et al. (2017) · Human Molecular Genetics

Sleep and Wakefulness ResearchCircadian rhythm and melatonin

Cited by 48