Marchetti, Piero

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

Lyssenko, V., Nagorny, C. L. F., Erdos, M. R., Wierup, N., Jonsson, A., Spégel, P., Bugliani, M., Saxena, R., Fex, M., Pulizzi, N., et al. (2009) · Nature Genetics

Pancreatic function and diabetesCircadian rhythm and melatonin

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Proceedings from an international consensus meeting on posttransplantation diabetes mellitus: recommendations and future directions

Sharif, A., Hecking, M., de Vries, A. P. J., Porrini, E., Hornum, M., Rasoul-Rockenschaub, S., Berlakovich, G., Krebs, M., Kautzky-Willer, A., Schernthaner, G., et al. (2014) · American Journal of Transplantation

Renal Transplantation Outcomes and TreatmentsDiabetes Management and Research

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Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion

Ling, C., Del Guerra, S., Lupi, R., Rönn, T., Granhall, C., Luthman, H., Masiello, P., Marchetti, P., Groop, L., & Del Prato, S. (2008) · Diabetologia

Pancreatic function and diabetesDiabetes and associated disorders

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Functional and Molecular Defects of Pancreatic Islets in Human Type 2 Diabetes

Del Guerra, S., Lupi, R., Marselli, L., Masini, M., Bugliani, M., Sbrana, S., Torri, S., Pollera, M., Boggi, U., Mosca, F., et al. (2005) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

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The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines

Eizirik, D. L., Sammeth, M., Bouckenooghe, T., Bottu, G., Sisino, G., Igoillo-Esteve, M., Ortis, F., Santin, I., Colli, M. L., Barthson, J., et al. (2012) · PLoS Genetics

Diabetes and associated disordersPancreatic function and diabetes

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Beta cell hubs dictate pancreatic islet responses to glucose

Johnston, N. R., Mitchell, R. K., Haythorne, E., Pessoa, M. P., Semplici, F., Ferrer, J., Piemonti, L., Marchetti, P., Bugliani, M., Bosco, D., et al. (2016) · Cell Metabolism

Pancreatic function and diabetesDiabetes and associated disorders

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DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

Volkmar, M., Dedeurwaerder, S., Cunha, D. A., Ndlovu, M. N., Defrance, M., Deplus, R., Calonne, E., Volkmar, U., Igoillo‐Esteve, M., Naamane, N., et al. (2012) · The EMBO Journal

Epigenetics and DNA MethylationPancreatic function and diabetes

Cited by 420

The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients

Marchetti, P., Bugliani, M., Lupi, R., Marselli, L., Masini, M., Boggi, U., Filipponi, F., Weir, G. C., Eizirik, D. L., & Cnop, M. (2007) · Diabetologia

Endoplasmic Reticulum Stress and DiseasePancreatic function and diabetes

Cited by 413

Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients

Anello, M., Lupi, R., Spampinato, D., Piro, S., Masini, M., Boggi, U., Del Prato, S., Rabuazzo, A. M., Purrello, F., & Marchetti, P. (2005) · Diabetologia

Pancreatic function and diabetesMitochondrial Function and Pathology

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Encapsulated islets for diabetes therapy: History, current progress, and critical issues requiring solution

Scharp, D. W., & Marchetti, P. (2014) · Advanced Drug Delivery Reviews

Pancreatic function and diabetesDiabetes Management and Research

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Gene Expression Profiles of Beta-Cell Enriched Tissue Obtained by Laser Capture Microdissection from Subjects with Type 2 Diabetes

Marselli, L., Thorne, J., Dahiya, S., Sgroi, D. C., Sharma, A., Bonner-Weir, S., Marchetti, P., & Weir, G. C. (2010) · PLoS ONE

Pancreatic function and diabetesDiabetes and associated disorders

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Lipotoxicity disrupts incretin-regulated human β cell connectivity

Hodson, D. J., Mitchell, R. K., Bellomo, E. A., Sun, G., Vinet, L., Meda, P., Li, D., Li, W.-H., Bugliani, M., Marchetti, P., et al. (2013) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes Treatment and Management

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Interferon-α mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes

Marroqui, L., Dos Santos, R. S., Op de beeck, A., Coomans de Brachène, A., Marselli, L., Marchetti, P., & Eizirik, D. L. (2017) · Diabetologia

Diabetes and associated disordersEndoplasmic Reticulum Stress and Disease

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ADCY5 Couples Glucose to Insulin Secretion in Human Islets

Hodson, D. J., Mitchell, R. K., Marselli, L., Pullen, T. J., Gimeno Brias, S., Semplici, F., Everett, K. L., Cooper, D. M. F., Bugliani, M., Marchetti, P., et al. (2014) · Diabetes

Pancreatic function and diabetesDiabetes and associated disorders

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Insulin Autoimmune Syndrome (Hirata Disease): A Comprehensive Review Fifty Years After Its First Description

Cappellani, D., Macchia, E., Falorni, A., & Marchetti, P. (2020) · Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy

Diabetes and associated disordersAdrenal Hormones and Disorders

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Are we overestimating the loss of beta cells in type 2 diabetes?

Marselli, L., Suleiman, M., Masini, M., Campani, D., Bugliani, M., Syed, F., Martino, L., Focosi, D., Scatena, F., Olimpico, F., et al. (2014) · Diabetologia

Pancreatic function and diabetesDiabetes Treatment and Management

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Glucose‐ and arginine‐induced insulin secretion by human pancreatic β‐cells: the role of HERG K + channels in firing and release

Rosati, B., Marchetti, P., Crociani, O., Lecchi, M., Lupi, R., Arcangeli, A., Olivotto, M., & Wanke, E. (2000) · The FASEB Journal

Pancreatic function and diabetesIon channel regulation and function

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Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress–Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis

Cunha, D. A., Igoillo-Esteve, M., Gurzov, E. N., Germano, C. M., Naamane, N., Marhfour, I., Fukaya, M., Vanderwinden, J.-M., Gysemans, C., Mathieu, C., et al. (2012) · Diabetes

Endoplasmic Reticulum Stress and DiseasePancreatic function and diabetes

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Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells

Demine, S., Schiavo, A. A., Marín-Cañas, S., Marchetti, P., Cnop, M., & Eizirik, D. L. (2020) · Stem Cell Research & Therapy

Pancreatic function and diabetesDiabetes and associated disorders

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IFN-α induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells

Coomans de Brachène, A., Dos Santos, R. S., Marroqui, L., Colli, M. L., Marselli, L., Mirmira, R. G., Marchetti, P., & Eizirik, D. L. (2018) · Diabetologia

Diabetes and associated disordersPancreatic function and diabetes

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The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward

Ndiaye, F. K., Huyvaert, M., Ortalli, A., Canouil, M., Lecoeur, C., Verbanck, M., Lobbens, S., Khamis, A., Marselli, L., Marchetti, P., et al. (2020) · International Journal of Obesity

Genetic Associations and EpidemiologyNutrition, Genetics, and Disease

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Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

Fine, N. H. F., Doig, C. L., Elhassan, Y. S., Vierra, N. C., Marchetti, P., Bugliani, M., Nano, R., Piemonti, L., Rutter, G. A., Jacobson, D. A., et al. (2018) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

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Upregulation of mitochondrial peripheral benzodiazepine receptor expression by cytokine-induced damage of human pancreatic islets

Trincavelli, M. L., Marselli, L., Falleni, A., Gremigni, V., Ragge, E., Dotta, F., Santangelo, C., Marchetti, P., Lucacchini, A., & Martini, C. (2002) · Journal of Cellular Biochemistry

Pancreatic function and diabetesDiabetes and associated disorders

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