Nathan, Carl

Nitric oxide as a secretory product of mammalian cells

Nathan, C. (1992) · The FASEB Journal

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 4,350

Neutrophils and immunity: challenges and opportunities

Nathan, C. (2006) · Nature reviews. Immunology

Neutrophil, Myeloperoxidase and Oxidative MechanismsInflammation biomarkers and pathways

Cited by 2,971

Points of control in inflammation

Nathan, C. (2002) · Nature

Immune Response and InflammationNF-κB Signaling Pathways

Cited by 2,738

Secretory products of macrophages.

Nathan, C. F. (1987) · Journal of Clinical Investigation

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 2,615

Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.

Xie, Q. W., Kashiwabara, Y., & Nathan, C. (1994) · Journal of Biological Chemistry

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 2,212

Nonresolving Inflammation

Nathan, C., & Ding, A. (2010) · Cell

Fatty Acid Research and HealthPhagocytosis and Immune Regulation

Cited by 2,183

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.

Nathan, C. F., Murray, H. W., Wiebe, M. E., & Rubin, B. Y. (1983) · The Journal of experimental medicine

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmune cells in cancer

Cited by 1,962

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells

Stuehr, D. J., & Nathan, C. F. (1989) · The Journal of Experimental Medicine

Immune cells in cancerNitric Oxide and Endothelin Effects

Cited by 1,744

Beyond oxidative stress: an immunologist's guide to reactive oxygen species

Nathan, C., & Cunningham-Bussel, A. (2013) · Nature Reviews Immunology

Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 1,619

Role of nitric oxide synthesis in macrophage antimicrobial activity

Nathan, C. F., & Hibbs, J. B. (1991) · Current Opinion in Immunology

Nitric Oxide and Endothelin EffectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 1,523

Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens

Nathan, C., & Shiloh, M. U. (2000) · Proceedings of the National Academy of Sciences

Neutrophil, Myeloperoxidase and Oxidative MechanismsTuberculosis Research and Epidemiology

Cited by 1,469

Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages

Schnappinger, D., Ehrt, S., Voskuil, M. I., Liu, Y., Mangan, J. A., Monahan, I. M., Dolganov, G., Efron, B., Butcher, P. D., Nathan, C., et al. (2003) · The Journal of Experimental Medicine

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 1,420

Identification of nitric oxide synthase as a protective locus against tuberculosis

MacMicking, J. D., North, R. J., LaCourse, R., Mudgett, J. S., Shah, S. K., & Nathan, C. F. (1997) · Proceedings of the National Academy of Sciences

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

Cited by 1,180

Reduced Biopterin as a Cofactor in the Generation of Nitrogen Oxides by Murine Macrophages

Kwon, N. S., Nathan, C. F., & Stuehr, D. J. (1989) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 570

Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

Yin, F., Banerjee, R., Thomas, B., Zhou, P., Qian, L., Jia, T., Ma, X., Ma, Y., Iadecola, C., Beal, M. F., et al. (2010) · Journal of Experimental Medicine

Neuroinflammation and Neurodegeneration MechanismsAmyotrophic Lateral Sclerosis Research

Cited by 480

Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide

Stuehr, D. J., Gross, S. S., Sakuma, I., Levi, R., & Nathan, C. F. (1989) · The Journal of experimental medicine

Nitric Oxide and Endothelin EffectsImmune cells in cancer

Cited by 457

A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis

Vandal, O. H., Pierini, L. M., Schnappinger, D., Nathan, C. F., & Ehrt, S. (2008) · Nature Medicine

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 368

MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival

Kim, Y., Zhou, P., Qian, L., Chuang, J.-Z., Lee, J., Li, C., Iadecola, C., Nathan, C., & Ding, A. (2007) · The Journal of Experimental Medicine

Immune Response and InflammationNeuroinflammation and Neurodegeneration Mechanisms

Cited by 234

Identification of a copper-binding metallothionein in pathogenic mycobacteria

Gold, B., Deng, H., Bryk, R., Vargas, D., Eliezer, D., Roberts, J., Jiang, X., & Nathan, C. (2008) · Nature Chemical Biology

Trace Elements in HealthTuberculosis Research and Epidemiology

Cited by 217

Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase

Nathan, C., Calingasan, N., Nezezon, J., Ding, A., Lucia, M. S., La Perle, K., Fuortes, M., Lin, M., Ehrt, S., Kwon, N. S., et al. (2005) · The Journal of Experimental Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 214

Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-gamma and tumor necrosis factor-alpha.

Maciejewski, J. P., Selleri, C., Sato, T., Cho, H. J., Keefer, L. K., Nathan, C. F., & Young, N. S. (1995) · Journal of Clinical Investigation

Hematopoietic Stem Cell TransplantationNitric Oxide and Endothelin Effects

Cited by 209

Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia

Yin, F., Dumont, M., Banerjee, R., Ma, Y., Li, H., Lin, M. T., Beal, M. F., Nathan, C., Thomas, B., & Ding, A. (2010) · The FASEB Journal

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 180