Beebe, David J.

The present and future role of microfluidics in biomedical research

Sackmann, E. K., Fulton, A. L., & Beebe, D. J. (2014) · Nature

Microfluidic and Capillary Electrophoresis ApplicationsMicrofluidic and Bio-sensing Technologies

Cited by 2,995

Biological implications of polydimethylsiloxane-based microfluidic cell culture

Regehr, K. J., Domenech, M., Koepsel, J. T., Carver, K. C., Ellison-Zelski, S. J., Murphy, W. L., Schuler, L. A., Alarid, E. T., & Beebe, D. J. (2009) · Lab on a Chip

Microfluidic and Capillary Electrophoresis Applications3D Printing in Biomedical Research

Cited by 719

Fundamentals of microfluidic cell culture in controlled microenvironments

Young, E. W. K., & Beebe, D. J. (2010) · Chemical Society Reviews

Microfluidic and Capillary Electrophoresis Applications3D Printing in Biomedical Research

Cited by 615

Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects

Sung, K. E., Yang, N., Pehlke, C., Keely, P. J., Eliceiri, K. W., Friedl, A., & Beebe, D. J. (2011) · Integr. Biol.

3D Printing in Biomedical ResearchCellular Mechanics and Interactions

Cited by 226

Microfluidic 3D models of cancer

Sung, K. E., & Beebe, D. J. (2014) · Advanced Drug Delivery Reviews

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 190

Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model

Ayuso, J. M., Truttschel, R., Gong, M. M., Humayun, M., Virumbrales-Munoz, M., Vitek, R., Felder, M., Gillies, S. D., Sondel, P., Wisinski, K. B., et al. (2019) · OncoImmunology

Immune Cell Function and Interaction3D Printing in Biomedical Research

Cited by 142

Managing evaporation for more robust microscale assays : Part 1. Volume loss in high throughput assays

Berthier, E., Warrick, J., Yu, H., & Beebe, D. J. (2008) · Lab on a Chip

Microfluidic and Capillary Electrophoresis ApplicationsInnovative Microfluidic and Catalytic Techniques Innovation

Cited by 114

Microfluidic model of ductal carcinoma in situ with 3D, organotypic structure

Bischel, L. L., Beebe, D. J., & Sung, K. E. (2015) · BMC Cancer

3D Printing in Biomedical ResearchCancer Cells and Metastasis

Cited by 110

Breast Fibroblasts and ECM Components Modulate Breast Cancer Cell Migration through the Secretion of MMPs in a 3D Microfluidic Co-Culture Model

Lugo-Cintrón, K. M., Gong, M. M., Ayuso, J. M., Tomko, L. A., Beebe, D. J., Virumbrales-Muñoz, M., & Ponik, S. M. (2020) · Cancers

Cellular Mechanics and InteractionsCancer Cells and Metastasis

Cited by 103

Human organotypic lymphatic vessel model elucidates microenvironment-dependent signaling and barrier function

Gong, M. M., Lugo-Cintron, K. M., White, B. R., Kerr, S. C., Harari, P. M., & Beebe, D. J. (2019) · Biomaterials

Lymphatic System and DiseasesLymphatic Disorders and Treatments

Cited by 87

Low-Volume Toolbox for the Discovery of Immunosuppressive Fungal Secondary Metabolites

Berthier, E., Lim, F. Y., Deng, Q., Guo, C.-J., Kontoyiannis, D. P., Wang, C. C. C., Rindy, J., Beebe, D. J., Huttenlocher, A., & Keller, N. P. (2013) · PLoS Pathogens

Microbial Natural Products and BiosynthesisAntifungal resistance and susceptibility

Cited by 63

Elucidating cancer-vascular paracrine signaling using a human organotypic breast cancer cell extravasation model

Humayun, M., Ayuso, J. M., Brenneke, R. A., Virumbrales-Muñoz, M., Lugo-Cintrón, K., Kerr, S., Ponik, S. M., & Beebe, D. J. (2021) · Biomaterials

Cancer Cells and MetastasisAngiogenesis and VEGF in Cancer

Cited by 46

Patient-specific organotypic blood vessels as an in vitro model for anti-angiogenic drug response testing in renal cell carcinoma

Jiménez-Torres, J. A., Virumbrales-Muñoz, M., Sung, K. E., Lee, M. H., Abel, E. J., & Beebe, D. J. (2019) · EBioMedicine

Angiogenesis and VEGF in Cancer3D Printing in Biomedical Research

Cited by 46

Toward improved in vitro models of human cancer

Ayuso, J. M., Park, K.-Y., Virumbrales-Muñoz, M., & Beebe, D. J. (2021) · APL Bioengineering

3D Printing in Biomedical ResearchCancer Cells and Metastasis

Cited by 40

Organotypic primary blood vessel models of clear cell renal cell carcinoma for single-patient clinical trials

Virumbrales-Muñoz, M., Chen, J., Ayuso, J., Lee, M., Abel, E. J., & Beebe, D. J. (2020) · Lab on a Chip

Angiogenesis and VEGF in Cancer3D Printing in Biomedical Research

Cited by 39

Microfluidic model with air-walls reveals fibroblasts and keratinocytes modulate melanoma cell phenotype, migration, and metabolism

Ayuso, J. M., Sadangi, S., Lares, M., Rehman, S., Humayun, M., Denecke, K. M., Skala, M. C., Beebe, D. J., & Setaluri, V. (2021) · Lab on a Chip

3D Printing in Biomedical ResearchCancer Cells and Metastasis

Cited by 39

Microphysiological head and neck cancer model identifies novel role of lymphatically secreted monocyte migration inhibitory factor in cancer cell migration and metabolism

Yada, R. C., Desa, D. E., Gillette, A. A., Bartels, E., Harari, P. M., Skala, M. C., Beebe, D. J., & Kerr, S. C. (2023) · Biomaterials

Macrophage Migration Inhibitory FactorLymphatic System and Diseases

Cited by 30

Models of renal cell carcinoma used to investigate molecular mechanisms and develop new therapeutics

Shapiro, D. D., Virumbrales-Muñoz, M., Beebe, D. J., & Abel, E. J. (2022) · Frontiers in Oncology

Renal cell carcinoma treatmentCancer Cells and Metastasis

Cited by 28

Transitions from mono- to co- to tri-culture uniquely affect gene expression in breast cancer, stromal, and immune compartments

Regier, M. C., Maccoux, L. J., Weinberger, E. M., Regehr, K. J., Berry, S. M., Beebe, D. J., & Alarid, E. T. (2016) · Biomedical Microdevices

3D Printing in Biomedical ResearchCancer Cells and Metastasis

Cited by 23

Microphysiological model of renal cell carcinoma to inform anti-angiogenic therapy

Virumbrales-Muñoz, M., Ayuso, J. M., Loken, J. R., Denecke, K. M., Rehman, S., Skala, M. C., Abel, E. J., & Beebe, D. J. (2022) · Biomaterials

3D Printing in Biomedical ResearchAngiogenesis and VEGF in Cancer

Cited by 20