Fundamentals of microfluidic cell culture in controlled microenvironments

Monolithic Microfabricated Valves and Pumps by Multilayer Soft Lithography

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Culture of Animal Cells

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Flow-mediated endothelial mechanotransduction

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Growth Factors, Matrices, and Forces Combine and Control Stem Cells

Discher, D. E., Mooney, D. J., & Zandstra, P. W. (2009) · Science · doi:10.1126/science.1171643 · Cited by 2,666 · see citing works

Soft Lithography in Biology and Biochemistry

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Cells on chips

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Physics and Applications of Microfluidics in Biology

Beebe, D. J., Mensing, G. A., & Walker, G. M. (2002) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.4.112601.125916 · Cited by 1,803 · see citing works

Magnetism and microfluidics

Pamme, N. (2005) · Lab on a Chip · doi:10.1039/b513005k · Cited by 1,133 · see citing works

Review on micro molding of thermoplastic polymers

Heckele, M., & Schomburg, W. K. (2003) · Journal of Micromechanics and Microengineering · doi:10.1088/0960-1317/14/3/r01 · Cited by 924 · see citing works

Biological implications of polydimethylsiloxane-based microfluidic cell culture

Regehr, K. J., Domenech, M., Koepsel, J. T., Carver, K. C., Ellison-Zelski, S. J., Murphy, W. L., Schuler, L. A., Alarid, E. T., & Beebe, D. J. (2009) · Lab on a Chip · doi:10.1039/b903043c · Cited by 719 · see citing works

Microfluidic devices for cellomics: a review

Andersson, H., & van den Berg, A. (2003) · Sensors and Actuators B Chemical · doi:10.1016/s0925-4005(03)00266-1 · Cited by 661 · see citing works

Cell Mechanics: Integrating Cell Responses to Mechanical Stimuli

Janmey, P. A., & McCulloch, C. A. (2007) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.9.060906.151927 · Cited by 631 · see citing works

Versatile, Fully Automated, Microfluidic Cell Culture System

Gómez-Sjöberg, R., Leyrat, A. A., Pirone, D. M., Chen, C. S., & Quake, S. R. (2007) · Analytical Chemistry · doi:10.1021/ac071311w · Cited by 619 · see citing works

The organizing principle: microenvironmental influences in the normal and malignant breast

Bissell, M. J., Radisky, D. C., Rizki, A., Weaver, V. M., & PETERSEN, O. W. (2002) · Differentiation · doi:10.1046/j.1432-0436.2002.700907.x · Cited by 602 · see citing works

Biomolecular gradients in cell culture systems

Keenan, T. M., & Folch, A. (2008) · Lab Chip · doi:10.1039/b711887b · Cited by 596 · see citing works

Cell migration into scaffolds under co-culture conditions in a microfluidic platform

Chung, S. H., Sudo, R., Mack, P. J., Wan, C.-R., Vickerman, V., & Kamm, R. D. (2008) · Lab on a Chip · doi:10.1039/b807585a · Cited by 517 · see citing works

Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems

Huh, D., Fujioka, H., Tung, Y., Futai, N., Paine, R., Grotberg, J. B., & Takayama, S. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610868104 · Cited by 496 · see citing works

Microfluidics technology for manipulation and analysis of biological cells

Yi, C., Li, C., Ji, S., & Yang, M. (2006) · Analytica Chimica Acta · doi:10.1016/j.aca.2005.12.037 · Cited by 479 · see citing works

A practical guide to microfluidic perfusion culture of adherent mammalian cells

Kim, L. Y., Toh, Y., Joel Voldman, B., & Yu, H. (2007) · Lab on a Chip · doi:10.1039/b704602b · Cited by 457 · see citing works

The organ microenvironment and cancer metastasis

Fidler, I. J. (2002) · Differentiation · doi:10.1046/j.1432-0436.2002.700904.x · Cited by 428 · see citing works

Computerized microfluidic cell culture using elastomeric channels and Braille displays

Gu, W., Zhu, X. A., Futai, N., Cho, B. S., & Takayama, S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0404353101 · Cited by 403 · see citing works

Analysis of single mammalian cells on-chip

Sims, C. E., & Allbritton, N. L. (2007) · Lab on a Chip · doi:10.1039/b615235j · Cited by 400 · see citing works

Microenvironment design considerations for cellular scale studies

Walker, G. M., Zeringue, H. C., & Beebe, D. J. (2004) · Lab on a Chip · doi:10.1039/b311214d · Cited by 387 · see citing works

Engineering microscale cellular niches for three-dimensional multicellular co-cultures

Huang, C. P., Lu, J., Seon, H., Lee, A. P., Flanagan, L. A., Kim, H.-Y., Putnam, A. J., & Jeon, N. L. (2009) · Lab on a Chip · doi:10.1039/b818401a · Cited by 384 · see citing works

Flow-induced deformation of shallow microfluidic channels

Gervais, T., El-Ali, J., Günther, A., & Jensen, K. F. (2006) · Lab on a Chip · doi:10.1039/b513524a · Cited by 361 · see citing works

Microenvironment-induced cancer metastasis

Rofstad, E. K. (2000) · International Journal of Radiation Biology · doi:10.1080/095530000138259 · Cited by 330 · see citing works

Microfluidic Endothelium for Studying the Intravascular Adhesion of Metastatic Breast Cancer Cells

Song, J. W., Cavnar, S. P., Walker, A. C., Luker, K. E., Gupta, M., Tung, Y.-C., Luker, G. D., & Takayama, S. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005756 · Cited by 317 · see citing works

An integrated microfluidic system for long-term perfusion culture and on-line monitoring of intestinal tissue models

Kimura, H., Yamamoto, T., Sakai, H., Sakai, Y., & Fujii, T. (2008) · Lab on a Chip · doi:10.1039/b717091b · Cited by 293 · see citing works

Culturing Life: How Cells Became Technologies

Landecker, H. L. (2007) · Cited by 283 · see citing works

Characterization and Resolution of Evaporation-Mediated Osmolality Shifts That Constrain Microfluidic Cell Culture in Poly(dimethylsiloxane) Devices

Heo, Y. S., Cabrera, L. M., Song, J. W., Futai, N., Tung, Y., Smith, G. D., & Takayama, S. (2006) · Analytical Chemistry · doi:10.1021/ac061990v · Cited by 245 · see citing works

Microfluidics meet cell biology: bridging the gap by validation and application of microscale techniques for cell biological assays

Paguirigan, A. L., & Beebe, D. J. (2008) · BioEssays · doi:10.1002/bies.20804 · Cited by 207 · see citing works

Combinatorial Signaling Microenvironments for Studying Stem Cell Fate

Flaim, C. J., Teng, D., Chien, S., & Bhatia, S. N. (2008) · Stem Cells and Development · doi:10.1089/scd.2007.0085 · Cited by 195 · see citing works

Flow rate analysis of a surface tension driven passive micropump

Berthier, E., & Beebe, D. J. (2007) · Lab on a Chip · doi:10.1039/b707637a · Cited by 191 · see citing works

Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments

LaBarge, M. A., Nelson, C. M., Villadsen, R., Fridriksdottir, A. J., Ruth, J. R., Stampfer, M. R., PETERSEN, O. W., & Bissell, M. J. (2008) · Integrative Biology · doi:10.1039/b816472j · Cited by 177 · see citing works

Automated cell culture in high density tubeless microfluidic device arrays

Meyvantsson, I., Warrick, J. W., Hayes, S. A., Skoien, A., & Beebe, D. J. (2008) · Lab on a Chip · doi:10.1039/b715375a · Cited by 172 · see citing works

A gel-free 3D microfluidic cell culture system

Ong, S.-M., Zhang, C., Toh, Y.-C., Kim, S. H., Foo, H. L., Tan, C. H., van Noort, D., Park, S., & Yu, H. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.04.022 · Cited by 172 · see citing works

Shrinky-Dink microfluidics: 3D polystyrene chips

Chen, C., Breslauer, D. N., Luna, J. I., Grimes, A., Chin, W., Lee, L. P., & Khine, M. (2008) · Lab on a Chip · doi:10.1039/b719029h · Cited by 152 · see citing works

Diffusion dependent cell behavior in microenvironments

Yu, H., Meyvantsson, I., Shkel, I. A., & Beebe, D. J. (2005) · Lab on a Chip · doi:10.1039/b504403k · Cited by 146 · see citing works

From the cellular perspective: exploring differences in the cellular baseline in macroscale and microfluidic cultures

Paguirigan, A. L., & Beebe, D. J. (2009) · Integrative Biology · doi:10.1039/b814565b · Cited by 136 · see citing works

A platform for assessing chemotactic migration within a spatiotemporally defined 3D microenvironment

Abhyankar, V. V., Toepke, M. W., Cortesio, C. L., Lokuta, M. A., Anna Huttenlocher, A., & Beebe, D. J. (2008) · Lab on a Chip · doi:10.1039/b803533d · Cited by 134 · see citing works

Hybrid microfluidics: A digital-to-channel interface for in-line sample processing and chemical separations

Abdelgawad, M. O., Watson, M. W. L., & Wheeler, A. R. (2009) · Lab on a Chip · doi:10.1039/b820682a · Cited by 122 · see citing works

Managing evaporation for more robust microscale assays : Part 1. Volume loss in high throughput assays

Berthier, E., Warrick, J., Yu, H., & Beebe, D. J. (2008) · Lab on a Chip · doi:10.1039/b717422e · Cited by 114 · see citing works

Hard Top Soft Bottom Microfluidic Devices for Cell Culture and Chemical Analysis

Mehta, G., Lee, J. S.-J., Cha, W., Tung, Y., Linderman, J. J., & Takayama, S. (2009) · Analytical Chemistry · doi:10.1021/ac802178u · Cited by 111 · see citing works

An active bubble trap and debubbler for microfluidic systems

Skelley, A. M., & Voldman, J. (2008) · Lab on a Chip · doi:10.1039/b807037g · Cited by 110 · see citing works

Rapid generation of spatially and temporally controllable long-range concentration gradients in a microfluidic device

Du, Y., Shim, J., Vidula, M. K., HANCOCK, M. J., Lo, E., Chung, B. G., Borenstein, J. T., Khabiry, M., Cropek, D. M., & Khademhosseini, A. (2008) · Lab on a Chip · doi:10.1039/b815990d · Cited by 89 · see citing works

A membrane-based microfluidic device for controlling the flux of platelet agonists into flowing blood

Neeves, K. B., & Diamond, S. L. (2008) · Lab on a Chip · doi:10.1039/b717824g · Cited by 85 · see citing works

Amperometric determination of nitric oxide derived from pulmonary artery endothelial cells immobilized in a microchip channel

Spence, D. M., Torrence, N. J., Kovarik, M. L., & Martin, R. S. (2004) · The Analyst · doi:10.1039/b410547h · Cited by 65 · see citing works

Integrated wavelength-selective optical waveguides for microfluidic-based laser-induced fluorescence detection

Bliss, C. L., McMullin, J. N., & Backhouse, C. (2007) · Lab on a Chip · doi:10.1039/b711601b · Cited by 57 · see citing works

Selective and tunable gradient device for cell culture and chemotaxis study

Kim, D., Lokuta, M. A., Anna Huttenlocher, A., & Beebe, D. J. (2009) · Lab on a Chip · doi:10.1039/b901613a · Cited by 56 · see citing works

A plate reader-compatible microchannel array for cell biology assays

Yu, H., Alexander, C. M., & Beebe, D. J. (2007) · Lab on a Chip · doi:10.1039/b612358a · Cited by 44 · see citing works

Automated High-Throughput Microchannel Assays for Cell Biology: Operational Optimization and Characterization

Puccinelli, J. P., Su, X., & Beebe, D. J. (2009) · JALA Journal of the Association for Laboratory Automation · doi:10.1016/j.jala.2009.10.002 · Cited by 34 · see citing works

Mass Transport and Shear Stress in a Microchannel Bioreactor: Numerical Simulation and Dynamic Similarity

Zeng, Y., Lee, T.-S., Yu, P., Roy, P., & Low, H. T. (2005) · Journal of Biomechanical Engineering · doi:10.1115/1.2170118 · Cited by 33 · see citing works

Computation of transient flow rates in passive pumping micro-fluidic systems

Chen, I.-J., Eckstein, E. C., & Lindner, E. (2008) · Lab on a Chip · doi:10.1039/b808660e · Cited by 28 · see citing works

Microfabricated curtains for controlled cell seeding in high throughput microfluidic systems

O’Neill, A. T., Monteiro-Riviere, N. A., & Walker, G. M. (2009) · Lab on a Chip · doi:10.1039/b819622b · Cited by 13 · see citing works

A practical guide to hydrogels for cell culture

Caliari, S. R., & Burdick, J. A. (2016) · Nature Methods · doi:10.1038/nmeth.3839 · Cited by 2,075 · see citing works

A guide to the organ-on-a-chip

Leung, C. M., de Haan, P., Ronaldson-Bouchard, K., Kim, G.-A., Ko, J., Rho, H. S., Chen, Z., Habibovic, P., Jeon, N. L., Takayama, S., et al. (2022) · Nature Reviews Methods Primers · doi:10.1038/s43586-022-00118-6 · Cited by 1,116 · see citing works

Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices

Halldorsson, S., Lucumi, E., Gómez-Sjöberg, R., & Fleming, R. M. T. (2015) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2014.07.029 · Cited by 1,027 · see citing works

Prebiotic Systems Chemistry: New Perspectives for the Origins of Life

Ruiz-Mirazo, K., Briones, C., & de la Escosura, A. (2014) · Chemical Reviews · doi:10.1021/cr2004844 · Cited by 930 · see citing works

Advances in Microfluidic Materials, Functions, Integration, and Applications

Nge, P. N., Rogers, C. I., & Woolley, A. T. (2013) · Chemical Reviews · doi:10.1021/cr300337x · Cited by 960 · see citing works

PDMS with designer functionalities—Properties, modifications strategies, and applications

Wolf, M., Salieb–Beugelaar, G. B., & Hunziker, P. (2018) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2018.06.001 · Cited by 855 · see citing works

Engineers are from PDMS-land, Biologists are from Polystyrenia

Berthier, E., Young, E. W. K., & Beebe, D. J. (2012) · Lab on a Chip · doi:10.1039/c2lc20982a · Cited by 800 · see citing works

Three-dimensional organotypic culture: experimental models of mammalian biology and disease

Shamir, E. R., & Ewald, A. J. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3873 · Cited by 719 · see citing works

Organ-on-a-chip: recent breakthroughs and future prospects

Wu, Q., Liu, J., Wang, X., Feng, L., Wu, J., Zhu, X., Wen, W., & Gong, X. (2020) · BioMedical Engineering OnLine · doi:10.1186/s12938-020-0752-0 · Cited by 704 · see citing works

Microfluidic blood–brain barrier model provides in vivo‐like barrier properties for drug permeability screening

Wang, Y. I., Abaci, H. E., & Shuler, M. L. (2016) · Biotechnology and Bioengineering · doi:10.1002/bit.26045 · Cited by 559 · see citing works

Micromilling: a method for ultra-rapid prototyping of plastic microfluidic devices

Guckenberger, D. J., de Groot, T. E., Wan, A. M. D., Beebe, D. J., & Young, E. W. K. (2015) · Lab on a Chip · doi:10.1039/c5lc00234f · Cited by 515 · see citing works

Application of microfluidic chip technology in pharmaceutical analysis: A review

Cui, P., & Wang, S. (2018) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2018.12.001 · Cited by 391 · see citing works

Droplet microfluidics: recent developments and future applications

Solvas, X. C. I., & deMello, A. J. (2010) · Chemical Communications · doi:10.1039/c0cc02474k · Cited by 352 · see citing works

Three-dimensional brain-on-a-chip with an interstitial level of flow and its application as an in vitro model of Alzheimer's disease

Park, J., Lee, B. K., Jeong, G. S., Hyun, J. K., Lee, C. J., & Lee, S. (2014) · Lab on a Chip · doi:10.1039/c4lc00962b · Cited by 351 · see citing works

Cell-Based Biosensors and Their Application in Biomedicine

Liu, Q., Wu, C., Cai, H., Hu, N., Zhou, J., & Wang, P. (2014) · Chemical Reviews · doi:10.1021/cr2003129 · Cited by 351 · see citing works

A three‐dimensional in vitro ovarian cancer coculture model using a high‐throughput cell patterning platform

Xu, F., Celli, J., Rizvi, I., Moon, S., Hasan, T., & Demirci, U. (2011) · Biotechnology Journal · doi:10.1002/biot.201000340 · Cited by 337 · see citing works

Scaffold-based 3D cell culture models in cancer research

Abuwatfa, W. H., Pitt, W. G., & Husseini, G. A. (2024) · Journal of Biomedical Science · doi:10.1186/s12929-024-00994-y · Cited by 347 · see citing works

Organ-on-a-chip platforms: a convergence of advanced materials, cells, and microscale technologies

Ahadian, S., Civitarese, R., Bannerman, D., Mohammadi, M. H., Lu, R., Wang, E., Davenport‐Huyer, L., Lai, B., Zhang, B., Zhao, Y., et al. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201700506 · Cited by 315 · see citing works

Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery

Vladisavljević, G. T., Khalid, N., Neves, M. A., Kuroiwa, T., Nakajima, M., Uemura, K., Ichikawa, S., & Kobayashi, I. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.07.017 · Cited by 314 · see citing works

Microfluidic approaches for cancer cell detection, characterization, and separation

Chen, J., Li, J., & Sun, Y. (2012) · Lab on a Chip · doi:10.1039/c2lc21273k · Cited by 301 · see citing works

In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology

Tsai, M., Kita, A., Leach, J., Rounsevell, R., Huang, J. N., Moake, J., Ware, R. E., Fletcher, D. A., & Lam, W. A. (2012) · Journal of Clinical Investigation · doi:10.1172/jci58753 · Cited by 297 · see citing works

Axon diodes for the reconstruction of oriented neuronal networks in microfluidic chambers

Peyrin, J., Deleglise, B., Saïas, L., Vignes, M., Gougis, P., Magnifico, S., Bétuing, S., Pietri, M., Caboche, J., Vanhoutte, P., et al. (2011) · Lab on a Chip · doi:10.1039/c1lc20014c · Cited by 277 · see citing works

Spheroids-on-a-chip: Recent advances and design considerations in microfluidic platforms for spheroid formation and culture

Moshksayan, K., Kashaninejad, N., Warkiani, M. E., Lock, J. G., Moghadas, H., Firoozabadi, B., Saidi, M. S., & Nguyen, N.-T. (2018) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2018.01.223 · Cited by 267 · see citing works

Tubeless microfluidic angiogenesis assay with three-dimensional endothelial-lined microvessels

Bischel, L. L., Young, E. W. K., Mader, B. R., & Beebe, D. J. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.11.005 · Cited by 266 · see citing works

Nanotoxicology and Nanosafety: Safety-by-Design and Testing at a Glance

Zielińska, A., Costa, B. P., Ferreira, M. V., Miguéis, D., Louros, J. M. S., Durazzo, A., Lucarini, M., Eder, P., Chaud, M. V., Morsink, M. A. J., et al. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17134657 · Cited by 247 · see citing works

Advances in passively driven microfluidics and lab-on-chip devices: a comprehensive literature review and patent analysis

Narayanamurthy, V., Jeroish, Z. E., Bhuvaneshwari, K. S., Bayat, P., Premkumar, R., Samsuri, F., & Yusoff, M. M. (2020) · RSC Advances · doi:10.1039/d0ra00263a · Cited by 237 · see citing works

Microfluidics for Manipulating Cells

Mu, X., Zheng, W., Sun, J., Zhang, W., & Jiang, X. (2012) · Small · doi:10.1002/smll.201200996 · Cited by 214 · see citing works

Microfluidic lung airway-on-a-chip with arrayable suspended gels for studying epithelial and smooth muscle cell interactions

Humayun, M., Chow, C., & Young, E. W. K. (2018) · Lab on a Chip · doi:10.1039/c7lc01357d · Cited by 209 · see citing works

Microfluidic devices for cell cultivation and proliferation

Tehranirokh, M., Kouzani, A. Z., Francis, P. S., & Kanwar, J. R. (2013) · Biomicrofluidics · doi:10.1063/1.4826935 · Cited by 202 · see citing works

Microfluidic platforms for cell cultures and investigations

Coluccio, M. L., Perozziello, G., Malara, N., Parrotta, E. I., Zhang, P., Gentile, F., Limongi, T., Raj, P. M., Cuda, G., Candeloro, P., et al. (2019) · Microelectronic Engineering · doi:10.1016/j.mee.2019.01.004 · Cited by 199 · see citing works

A modular approach to create a neurovascular unit-on-a-chip

Achyuta, A. K. H., Conway, A. J., Crouse, R. B., Bannister, E. C., Lee, R. N., Katnik, C. P., Behensky, A. A., Cuevas, J., & Sundaram, S. (2012) · Lab on a Chip · doi:10.1039/c2lc41033h · Cited by 191 · see citing works

Rapid formation of size-controllable multicellular spheroids via 3D acoustic tweezers

Chen, K., Wu, M., Guo, F., Li, P., Chan, C. Y., Mao, Z., Li, S., Ren, L., Zhang, R., & Huang, T. J. (2016) · Lab on a Chip · doi:10.1039/c6lc00444j · Cited by 181 · see citing works

Rapid Prototyping of Arrayed Microfluidic Systems in Polystyrene for Cell-Based Assays

Young, E. W. K., Berthier, E., Guckenberger, D. J., Sackmann, E. K., Lamers, C., Meyvantsson, I., Anna Huttenlocher, A., & Beebe, D. J. (2011) · Analytical Chemistry · doi:10.1021/ac102897h · Cited by 172 · see citing works

Development of glass-based microfluidic devices: A review on its fabrication and biologic applications

Aralekallu, S., Boddula, R., & Singh, V. (2022) · Materials & Design · doi:10.1016/j.matdes.2022.111517 · Cited by 176 · see citing works

Multi-analyte biosensor interface for real-time monitoring of 3D microtissue spheroids in hanging-drop networks

Misun, P., Rothe, J., Schmid, Y. R. F., Hierlemann, A., & Frey, O. (2016) · Microsystems & Nanoengineering · doi:10.1038/micronano.2016.22 · Cited by 150 · see citing works

Recent Advances on Cell Culture Platforms for In Vitro Drug Screening and Cell Therapies: From Conventional to Microfluidic Strategies

Cardoso, B. D., Castanheira, E. M. S., Lanceros-Méndez, S., & Cardoso, V. F. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202202936 · Cited by 168 · see citing works

PDMS-Based Microfluidic Devices for Cell Culture

Torino, S., Corrado, B., Iodice, M., & Coppola, G. (2018) · Inventions · doi:10.3390/inventions3030065 · Cited by 159 · see citing works

3D bioprinting: improving<i>in vitro</i>models of metastasis with heterogeneous tumor microenvironments

Albritton, J. L., & Miller, J. S. (2017) · Disease Models &amp; Mechanisms · doi:10.1242/dmm.025049 · Cited by 154 · see citing works

In Vitro Microfluidic Models for Neurodegenerative Disorders

Osaki, T., Shin, Y., Sivathanu, V., Campisi, M., & Kamm, R. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201700489 · Cited by 127 · see citing works

Microfluidics applications for high-throughput single cell sequencing

Zhou, W.-M., Yan, Y., Guo, Q.-R., Ji, H., Wang, H., Xu, T.-T., Makabel, B., Pilarsky, C. P., He, G., Yu, X.-Y., et al. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-01045-6 · Cited by 146 · see citing works

Cells, tissues, and organs on chips: challenges and opportunities for the cancer tumor microenvironment

Young, E. W. K. (2013) · Integrative Biology · doi:10.1039/c3ib40076j · Cited by 144 · see citing works

Online oxygen monitoring using integrated inkjet-printed sensors in a liver-on-a-chip system

Moya, A., Ortega‐Ribera, M., Villalba, X. G., Sowade, E., Zea, M., Illa, X., Ramón, E., Villa, R., Gracia‐Sancho, J., & Gabriel, G. (2018) · Lab on a Chip · doi:10.1039/c8lc00456k · Cited by 146 · see citing works

Characterization and evaluation of 3D printed microfluidic chip for cell processing

Lee, J. M., Zhang, M., & Yeong, W. Y. (2016) · Microfluidics and Nanofluidics · doi:10.1007/s10404-015-1688-8 · Cited by 142 · see citing works

Understanding the Impact of 2D and 3D Fibroblast Cultures on In Vitro Breast Cancer Models

Sung, K. E., Su, X., Berthier, E., Pehlke, C. A., Friedl, A., & Beebe, D. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076373 · Cited by 138 · see citing works

Microfluidic devices for studying heterotypic cell-cell interactions and tissue specimen cultures under controlled microenvironments

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Multi-Organs-on-Chips: Towards Long-Term Biomedical Investigations

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