Gasparini, Laura

Antidiabetic drug metformin (Glucophage R ) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription

Chen, Y., Zhou, K., Wang, R., Liu, Y., Kwak, Y.-D., Ma, T., Thompson, R. C., Zhao, Y., Smith, L., Gasparini, L., et al. (2009) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 390

Non‐steroidal anti‐inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action

Gasparini, L., Ongini, E., & Wenk, G. (2004) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 226

Communication breaks-Down: From neurodevelopment defects to cognitive disabilities in Down syndrome

Contestabile, A., Benfenati, F., & Gasparini, L. (2010) · Progress in Neurobiology

Down syndrome and intellectual disability researchAlzheimer's disease research and treatments

Cited by 134

Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability

Gasparini, L., Anthony Crowther, R., Martin, K. R., Berg, N., Coleman, M., Goedert, M., & Spillantini, M. G. (2011) · Neurobiology of Aging

Alzheimer's disease research and treatmentsGlaucoma and retinal disorders

Cited by 133

Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy

Barini, E., Antico, O., Zhao, Y., Asta, F., Tucci, V., Catelani, T., Marotta, R., Xu, H., & Gasparini, L. (2016) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 126

Effect of energy shortage and oxidative stress on amyloid precursor protein metabolism in COS cells

Gasparini, L., Racchi, M., Benussi, L., Curti, D., Binetti, G., Bianchetti, A., Trabucchi, M., & Govoni, S. (1997) · Neuroscience Letters

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 89

Oxidative metabolism in cultured fibroblasts derived from sporadic Alzheimer's disease (AD) patients

Curti, D., Rognoni, F., Gasparini, L., Cattaneo, A., Paolillo, M., Racchi, M., Zani, L., Bianchetti, A., Trabucchi, M., Bergamaschi, S., et al. (1997) · Neuroscience Letters

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 80

N368-Tau fragments generated by legumain are detected only in trace amount in the insoluble Tau aggregates isolated from AD brain

Schlegel, K., Awwad, K., Heym, R. G., Holzinger, D., Doell, A., Barghorn, S., Jahn, T. R., Klein, C., Mordashova, Y., Schulz, M., et al. (2019) · Acta Neuropathologica Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 30