Skripuletz, Thomas

Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination

Skripuletz, T., Hackstette, D., Bauer, K., Gudi, V., Pul, R., Voss, E., Berger, K., Kipp, M., Baumgärtner, W., & Stangel, M. (2013) · Brain

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 376

Glial response during cuprizone-induced de- and remyelination in the CNS: lessons learned

Gudi, V., Gingele, S., Skripuletz, T., & Stangel, M. (2014) · Frontiers in Cellular Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 375

Cortical Demyelination Is Prominent in the Murine Cuprizone Model and Is Strain-Dependent

Skripuletz, T., Lindner, M., Kotsiari, A., Garde, N., Fokuhl, J., Linsmeier, F., Trebst, C., & Stangel, M. (2008) · The American Journal of Pathology

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 271

Regional differences between grey and white matter in cuprizone induced demyelination

Gudi, V., Moharregh-Khiabani, D., Skripuletz, T., Koutsoudaki, P. N., Kotsiari, A., Skuljec, J., Trebst, C., & Stangel, M. (2009) · Brain Research

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 252

Characterisation of microglia during de- and remyelination: Can they create a repair promoting environment?

Voß, E. V., Škuljec, J., Gudi, V., Skripuletz, T., Pul, R., Trebst, C., & Stangel, M. (2012) · Neurobiology of Disease

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 202

Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration

Molina-Gonzalez, I., Holloway, R. K., Jiwaji, Z., Dando, O., Kent, S. A., Emelianova, K., Lloyd, A. F., Forbes, L. H., Mahmood, A., Skripuletz, T., et al. (2023) · Nature Communications

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 176

CXCL10 Triggers Early Microglial Activation in the Cuprizone Model

Clarner, T., Janssen, K., Nellessen, L., Stangel, M., Skripuletz, T., Krauspe, B., Hess, F.-M., Denecke, B., Beutner, C., Linnartz-Gerlach, B., et al. (2015) · The Journal of Immunology

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 150

Cuprizone [Bis(Cyclohexylidenehydrazide)] is Selectively Toxic for Mature Oligodendrocytes

Bénardais, K., Kotsiari, A., Škuljec, J., Koutsoudaki, P. N., Gudi, V., Singh, V., Vulinović, F., Skripuletz, T., & Stangel, M. (2013) · Neurotoxicity Research

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 148

Demyelination of the hippocampus is prominent in the cuprizone model

Koutsoudaki, P. N., Skripuletz, T., Gudi, V., Moharregh-Khiabani, D., Hildebrandt, H., Trebst, C., & Stangel, M. (2009) · Neuroscience Letters

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 119

Cerebellar Cortical Demyelination in the Murine Cuprizone Model

Skripuletz, T., Bussmann, J., Gudi, V., Koutsoudaki, P. N., Pul, R., Moharregh‐Khiabani, D., Lindner, M., & Stangel, M. (2010) · Brain Pathology

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 108

Spatial and temporal profiles of growth factor expression during CNS demyelination reveal the dynamics of repair priming

Gudi, V., Škuljec, J., Yildiz, Ö., Frichert, K., Skripuletz, T., Moharregh-Khiabani, D., Voß, E., Wissel, K., Wolter, S., & Stangel, M. (2011) · PLoS ONE

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 103

Synaptophysin Is a Reliable Marker for Axonal Damage

Gudi, V., Gai, L., Herder, V., Tejedor, L. S., Kipp, M., Amor, S., Sühs, K.-W., Hansmann, F., Beineke, A., Baumgärtner, W., et al. (2017) · Journal of Neuropathology & Experimental Neurology

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 87

Delayed Demyelination and Impaired Remyelination in Aged Mice in the Cuprizone Model

Gingele, S., Henkel, F., Heckers, S., Moellenkamp, T. M., Hümmert, M. W., Skripuletz, T., Stangel, M., & Gudi, V. (2020) · Cells

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 53

The increasing role of Kappa free light chains in the diagnosis of multiple sclerosis

Konen, F. F., Schwenkenbecher, P., Jendretzky, K. F., Gingele, S., Sühs, K.-W., Tumani, H., Süße, M., & Skripuletz, T. (2021) · Cells

Multiple Sclerosis Research StudiesPeripheral Neuropathies and Disorders

Cited by 47

Lack of cuprizone-induced demyelination in the murine spinal cord despite oligodendroglial alterations substantiates the concept of site-specific susceptibilities of the central nervous system: Scientific correspondence

Herder, V., Hansmann, F., Stangel, M., Skripuletz, T., Baumgärtner, W., & Beineke, A. (2011) · Neuropathology and Applied Neurobiology

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 45

Remyelination after cuprizone induced demyelination is accelerated in mice deficient in the polysialic acid synthesizing enzyme St8siaIV

Koutsoudaki, P. N., Hildebrandt, H., Gudi, V., Skripuletz, T., Škuljec, J., & Stangel, M. (2010) · Neuroscience

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 37

Oligoclonal bands and kappa free light chains: Competing parameters or complementary biomarkers?

Konen, F. F., Wurster, U., Schwenkenbecher, P., Gerritzen, A., Groß, C. C., Eichhorn, P., Harrer, A., Isenmann, S., Lewczuk, P., Lewerenz, J., et al. (2025) · Autoimmunity Reviews

Multiple Sclerosis Research StudiesPeripheral Neuropathies and Disorders

Cited by 31

Lipopolysaccharide delays demyelination and promotes oligodendrocyte precursor proliferation in the central nervous system

Skripuletz, T., Miller, E., Grote, L., Gudi, V., Pul, R., Voss, E., Škuljec, J., Moharregh-Khiabani, D., Trebst, C., & Stangel, M. (2011) · Brain, Behavior, and Immunity

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 31

Investigation of Cuprizone Inactivation by Temperature

Heckers, S., Held, N., Kronenberg, J., Skripuletz, T., Bleich, A., Gudi, V., & Stangel, M. (2017) · Neurotoxicity Research

Multiple Sclerosis Research StudiesImmunotoxicology and immune responses

Cited by 7

Implications of monoclonal gammopathy and isoelectric focusing pattern 5 on the free light chain kappa diagnostics in cerebrospinal fluid

Hannich, M. J., Konen, F. F., Gag, K., Alkhayer, A., Türker, S. N., Budde, K., Nauck, M., Wurster, U., Dressel, A., Skripuletz, T., et al. (2025) · Clinical Chemistry and Laboratory Medicine (CCLM)

Multiple Sclerosis Research StudiesClinical Laboratory Practices and Quality Control

Cited by 7

Added value of optic nerve lesions for multiple sclerosis diagnostic criteria

Mahmoudi, N., Renne, J., Konen, F. F., Jendretzky, K. F., Möhn, N., Grote-Levi, L., Gingele, S., Hümmert, M. W., Schwenkenbecher, P., Soldatov, A., et al. (2025) · Journal of Neurology

Multiple Sclerosis Research StudiesClinical Reasoning and Diagnostic Skills

Cited by 4

Applying the 2024-revised McDonald criteria for multiple sclerosis using conventional diagnostic tools: a single-centre prospective cohort study in Germany

Konen, F. F., Mahmoudi, N., Albers, L. M., Arrambide, G., Streichert, A. L., Haar, M., Soldatov, A., Bucak, E., Jendretzky, K. F., Nay, S., et al. (2026) · eClinicalMedicine

Multiple Sclerosis Research StudiesClinical Reasoning and Diagnostic Skills

Cited by 0