Jiang, Hualiang

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir

Yin, W., Mao, C., Luan, X., Shen, D.-D., Shen, Q., Su, H., Wang, X., Zhou, F., Zhao, W., Gao, M., et al. (2020) · Science

SARS-CoV-2 and COVID-19 ResearchEnzyme Structure and Function

Cited by 1,219

TransformerCPI: improving compound–protein interaction prediction by sequence-based deep learning with self-attention mechanism and label reversal experiments

Chen, L., Tan, X., Wang, D., Zhong, F., Liu, X., Yang, T., Luo, X., Chen, K., Jiang, H., & Zheng, M. (2020) · Bioinformatics

Computational Drug Discovery MethodsMachine Learning in Bioinformatics

Cited by 607

beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain.

Jiang, H., Burdick, D., Glabe, C. G., Cotman, C. W., & Tenner, A. J. (1994) · The Journal of Immunology

Alzheimer's disease research and treatmentsComplement system in diseases

Cited by 330

Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target

Zhang, B., Li, J., Yang, X., Wu, L., Zhang, J., Yang, Y., Zhao, Y., Zhang, L., Yang, X., Yang, X., et al. (2019) · Cell

Tuberculosis Research and EpidemiologyDrug Transport and Resistance Mechanisms

Cited by 263

Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors

Yang, Y., Zhang, R., Li, Z., Mei, L., Wan, S., Ding, H., Chen, Z., Xing, J., Feng, H., Han, J., et al. (2020) · Journal of Medicinal Chemistry

Histone Deacetylase Inhibitors ResearchProtein Degradation and Inhibitors

Cited by 132

Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations

Zhou, C., Fan, Z., Zhou, Z., Li, Y., Cui, R., Liu, C., Zhou, G., Diao, X., Jiang, H., Zheng, M., et al. (2022) · Journal of Medicinal Chemistry

Protein Degradation and InhibitorsProtein Kinase Regulation and GTPase Signaling

Cited by 94

AST1306, A Novel Irreversible Inhibitor of the Epidermal Growth Factor Receptor 1 and 2, Exhibits Antitumor Activity Both In Vitro and In Vivo

Xie, H., Lin, L., Tong, L., Jiang, Y., Zheng, M., Chen, Z., Jiang, X., Zhang, X., Ren, X., Qu, W., et al. (2011) · PLoS ONE

HER2/EGFR in Cancer ResearchLung Cancer Treatments and Mutations

Cited by 48

Recent advances in predicting protein–protein interactions with the aid of artificial intelligence algorithms

Li, S., Wu, S., Wang, L., Li, F., Jiang, H., & Bai, F. (2022) · Current Opinion in Structural Biology

Machine Learning in BioinformaticsBioinformatics and Genomic Networks

Cited by 42

Estimation of acute oral toxicity in rat using local lazy learning

Lu, J., Peng, J., Wang, J., Shen, Q., Bi, Y., Gong, L., Zheng, M., Luo, X., Zhu, W., Jiang, H., et al. (2014) · Journal of Cheminformatics

Computational Drug Discovery MethodsAnimal testing and alternatives

Cited by 42

Structural basis of peptide recognition and activation of endothelin receptors

Ji, Y., Duan, J., Yuan, Q., He, X., Yang, G., Zhu, S., Wu, K., Hu, W., Gao, T., Cheng, X., et al. (2023) · Nature Communications

Receptor Mechanisms and SignalingNitric Oxide and Endothelin Effects

Cited by 31