Arosio, Paolo

The ferritins: molecular properties, iron storage function and cellular regulation

Harrison, P. M., & Arosio, P. (1996) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 2,667

Ferritins: A family of molecules for iron storage, antioxidation and more

Arosio, P., Ingrassia, R., & Cavadini, P. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 886

Solving the structure of human H ferritin by genetically engineering intermolecular crystal contacts

Lawson, D. M., Artymiuk, P. J., Yewdall, S. J., Smith, J. M. A., Livingstone, J. C., Treffry, A., Luzzago, A., Levi, S., Arosio, P., Cesareni, G., et al. (1991) · Nature

Iron Metabolism and DisordersEnzyme Structure and Function

Cited by 777

The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging

Zecca, L., Stroppolo, A., Gatti, A., Tampellini, D., Toscani, M., Gallorini, M., Giaveri, G., Arosio, P., Santambrogio, P., Fariello, R. G., et al. (2004) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolism

Cited by 495

Ferritin, cellular iron storage and regulation

Arosio, P., Elia, L., & Poli, M. (2017) · IUBMB Life

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 480

A human mitochondrial ferritin encoded by an intronless gene

Levi, S., Corsi, B., Bosisio, M., Invernizzi, R., Volz, A., Sanford, D., Arosio, P., & Drysdale, J. (2001) · Journal of Biological Chemistry

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 400

A quantitative analysis of isoferritins in select regions of aged, parkinsonian, and Alzheimer's diseased brains

Connor, J. R., Snyder, B. S., Arosio, P., Loeffler, D. A., & LeWitt, P. (1995) · Journal of Neurochemistry

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 317

Identification of the ferroxidase centre in ferritin

Lawson, D. M., Treffry, A., Artymiuk, P. J., Harrison, P. M., Yewdall, S. J., Luzzago, A., Cesareni, G., Levi, S., & Arosio, P. (1989) · FEBS Letters

Iron Metabolism and DisordersMetal-Catalyzed Oxygenation Mechanisms

Cited by 312

Ferritin functions as a proinflammatory cytokine via iron‐independent protein kinase C zeta/nuclear factor kappaB–regulated signaling in rat hepatic stellate cells†

Ruddell, R. G., Hoang‐Le, D., Barwood, J. M., Rutherford, P. S., Piva, T. J., Watters, D. J., Santambrogio, P., Arosio, P., & Ramm, G. A. (2009) · Hepatology

Liver physiology and pathologyIron Metabolism and Disorders

Cited by 298

Overexpression of Wild Type and Mutated Human Ferritin H-chain in HeLa Cells

Cozzi, A., Corsi, B., Levi, S., Santambrogio, P., Albertini, A., & Arosio, P. (2000) · Journal of Biological Chemistry

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 242

Mitochondrial Ferritin: A New Player in Iron Metabolism

Drysdale, J., Arosio, P., Invernizzi, R., Cazzola, M., Volz, A., Corsi, B., Biasiotto, G., & Levi, S. (2002) · Blood Cells, Molecules, and Diseases

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 180

Dysregulation of Iron Homeostasis in the CNS Contributes to Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis

Jeong, S. Y., Rathore, K. I., Schulz, K., Ponka, P., Arosio, P., & David, S. (2009) · The Journal of Neuroscience

Amyotrophic Lateral Sclerosis ResearchNeurological diseases and metabolism

Cited by 174

Biology of ferritin in mammals: an update on iron storage, oxidative damage and neurodegeneration

Finazzi, D., & Arosio, P. (2014) · Archives of Toxicology

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 166

Heparin: a potent inhibitor of hepcidin expression in vitro and in vivo

Poli, M., Girelli, D., Campostrini, N., Maccarinelli, F., Finazzi, D., Luscieti, S., Nai, A., & Arosio, P. (2011) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 148

Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin

Cozzi, A., Corsi, B., Levi, S., Santambrogio, P., Biasiotto, G., & Arosio, P. (2004) · Blood

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 132

Hepcidin antagonists for potential treatments of disorders with hepcidin excess

Poli, M., Asperti, M., Ruzzenenti, P., Regoni, M., & Arosio, P. (2014) · Frontiers in Pharmacology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 124

Heavy chain ferritin activates regulatory T cells by induction of changes in dendritic cells

Gray, C. P., Arosio, P., & Hersey, P. (2002) · Blood

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 118

Crystal Structure and Biochemical Properties of the Human Mitochondrial Ferritin and its Mutant Ser144Ala

Langlois d'Estaintot, B., Santambrogio, P., Granier, T., Gallois, B., Chevalier, J. M., Précigoux, G., Levi, S., & Arosio, P. (2004) · Journal of Molecular Biology

Iron Metabolism and DisordersEnzyme Structure and Function

Cited by 113

The importance of eukaryotic ferritins in iron handling and cytoprotection

Arosio, P., Carmona, F., Gozzelino, R., Maccarinelli, F., & Poli, M. (2015) · Biochemical Journal

Iron Metabolism and DisordersHemoglobin structure and function

Cited by 104

Analysis of Ferritins in Lymphoblastoid Cell Lines and in the Lens of Subjects With Hereditary Hyperferritinemia-Cataract Syndrome

Levi, S., Girelli, D., Perrone, F., Pasti, M., Beaumont, C., Corrocher, R., Albertini, A., & Arosio, P. (1998) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 96

Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis

Silvestri, L., Pagani, A., Fazi, C., Gerardi, G., Levi, S., Arosio, P., & Camaschella, C. (2007) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 84

Immunosuppressive effects of melanoma-derived heavy-chain ferritin are dependent on stimulation of IL-10 production

Gray, C. P., Franco, A. V., Arosio, P., & Hersey, P. (2001) · International Journal of Cancer

Immune cells in cancerImmunotherapy and Immune Responses

Cited by 70

Mutant Ferritin L-chains That Cause Neurodegeneration Act in a Dominant-negative Manner to Reduce Ferritin Iron Incorporation

Luscieti, S., Santambrogio, P., Langlois d'Estaintot, B., Granier, T., Cozzi, A., Poli, M., Gallois, B., Finazzi, D., Cattaneo, A., Levi, S., et al. (2010) · Journal of Biological Chemistry

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 51

Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder

Cozzi, A., Santambrogio, P., Corsi, B., Campanella, A., Arosio, P., & Levi, S. (2006) · Neurobiology of Disease

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 38