Howes, Oliver D.

The clinical significance of duration of untreated psychosis: an umbrella review and random‐effects meta‐analysis

Howes, O. D., Whitehurst, T., Shatalina, E., Townsend, L., Onwordi, E. C., Mak, T. L. A., Arumuham, A., O’Brien, O., Lobo, M., Vano, L., et al. (2021) · World Psychiatry

Schizophrenia research and treatmentMental Health Treatment and Access

Cited by 243

Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

Onwordi, E. C., Halff, E. F., Whitehurst, T., Mansur, A., Cotel, M.-C., Wells, L., Creeney, H., Bonsall, D., Rogdaki, M., Shatalina, E., et al. (2020) · Nature Communications

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 243

The methodology of TSPO imaging with positron emission tomography

Turkheimer, F. E., Rizzo, G., Bloomfield, P. S., Howes, O., Zanotti-Fregonara, P., Bertoldo, A., & Veronese, M. (2015) · Biochemical Society Transactions

Neuroinflammation and Neurodegeneration MechanismsMedical Imaging Techniques and Applications

Cited by 238

Abnormal Frontostriatal Interactions in People With Prodromal Signs of Psychosis: A Multimodal Imaging Study

Fusar-Poli, P., Howes, O. D., Allen, P., Broome, M., Valli, I., Asselin, M.-C., Grasby, P. M., & McGuire, P. K. (2010) · Archives of General Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 234

A Test of the Transdiagnostic Dopamine Hypothesis of Psychosis Using Positron Emission Tomographic Imaging in Bipolar Affective Disorder and Schizophrenia

Jauhar, S., Nour, M. M., Veronese, M., Rogdaki, M., Bonoldi, I., Azis, M., Turkheimer, F., McGuire, P., Young, A. H., & Howes, O. D. (2017) · JAMA Psychiatry

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 233

Dopaminergic basis of salience dysregulation in psychosis

Winton-Brown, T. T., Fusar-Poli, P., Ungless, M. A., & Howes, O. D. (2014) · Trends in Neurosciences

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 231

Is psychosis a multisystem disorder? A meta-review of central nervous system, immune, cardiometabolic, and endocrine alterations in first-episode psychosis and perspective on potential models

Pillinger, T., D’Ambrosio, E., McCutcheon, R., & Howes, O. D. (2019) · Molecular Psychiatry

Schizophrenia research and treatmentTryptophan and brain disorders

Cited by 230

Alterations in the serotonin system in schizophrenia: A systematic review and meta-analysis of postmortem and molecular imaging studies

Selvaraj, S., Arnone, D., Cappai, A., & Howes, O. (2014) · Neuroscience & Biobehavioral Reviews

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 223

Auditory verbal hallucinations and continuum models of psychosis: A systematic review of the healthy voice-hearer literature

Baumeister, D., Sedgwick, O., Howes, O., & Peters, E. (2017) · Clinical Psychology Review

Hallucinations in medical conditionsSchizophrenia research and treatment

Cited by 220

Effects of long-term prolactin-raising antipsychotic medication on bone mineral density in patients with schizophrenia

Meaney, A. M., Smith, S., Howes, O. D., O'Brien, M., Murray, R. M., & O'Keane, V. (2004) · British Journal of Psychiatry

Schizophrenia research and treatmentBone health and osteoporosis research

Cited by 217

Neuroinflammation in schizophrenia: meta-analysis of in vivo microglial imaging studies

Marques, T. R., Ashok, A. H., Pillinger, T., Veronese, M., Turkheimer, F. E., Dazzan, P., Sommer, I. E. C., & Howes, O. D. (2019) · Psychological Medicine

Schizophrenia research and treatmentNeuroinflammation and Neurodegeneration Mechanisms

Cited by 213

Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical high risk for psychosis

Fusar-Poli, P., Howes, O. D., Allen, P., Broome, M., Valli, I., Asselin, M.-C., Montgomery, A. J., Grasby, P. M., & McGuire, P. (2011) · Molecular Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 207

Neural and Behavioral Correlates of Aberrant Salience in Individuals at Risk for Psychosis

Roiser, J. P., Howes, O. D., Chaddock, C. A., Joyce, E. M., & McGuire, P. (2013) · Schizophrenia Bulletin

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 205

A neurobiological hypothesis for the classification of schizophrenia: Type A (hyperdopaminergic) and type B (normodopaminergic)

Howes, O. D., & Kapur, S. (2014) · British Journal of Psychiatry

Schizophrenia research and treatmentMental Health and Psychiatry

Cited by 203

Midbrain dopamine function in schizophrenia and depression: A post-mortem and positron emission tomographic imaging study

Howes, O. D., Williams, M., Ibrahim, K., Leung, G., Egerton, A., McGuire, P. K., & Turkheimer, F. (2013) · Brain

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 198

A Meta-analysis of Immune Parameters, Variability, and Assessment of Modal Distribution in Psychosis and Test of the Immune Subgroup Hypothesis

Pillinger, T., Osimo, E. F., Brugger, S., Mondelli, V., McCutcheon, R. A., & Howes, O. D. (2019) · Schizophrenia Bulletin

Tryptophan and brain disordersSchizophrenia research and treatment

Cited by 190

Determinants of treatment response in first-episode psychosis: an 18F-DOPA PET study

Jauhar, S., Veronese, M., Nour, M. M., Rogdaki, M., Hathway, P., Turkheimer, F. E., Stone, J., Egerton, A., McGuire, P., Kapur, S., et al. (2019) · Molecular Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 183

Transition to Psychosis Associated With Prefrontal and Subcortical Dysfunction in Ultra High-Risk Individuals

Allen, P., Luigjes, J., Howes, O. D., Egerton, A., Hirao, K., Valli, I., Kambeitz, J., Fusar-Poli, P., Broome, M., & McGuire, P. (2012) · Schizophrenia Bulletin

Schizophrenia research and treatmentPsychopathy, Forensic Psychiatry, Sexual Offending

Cited by 129

Glucagon-Like Peptide 1 Receptor Agonists and Mental Health: A Systematic Review and Meta-Analysis

Pierret, A. C. S., Mizuno, Y., Saunders, P., Lim, E., De Giorgi, R., Howes, O. D., McCutcheon, R. A., McGowan, B., Sen Gupta, P., Smith, D., et al. (2025) · JAMA Psychiatry

Diabetes Treatment and ManagementPharmacology and Obesity Treatment

Cited by 116

The relationship between cortical glutamate and striatal dopamine in first-episode psychosis: a cross-sectional multimodal PET and magnetic resonance spectroscopy imaging study

Jauhar, S., McCutcheon, R., Borgan, F., Veronese, M., Nour, M., Pepper, F., Rogdaki, M., Stone, J., Egerton, A., Turkheimer, F., et al. (2018) · The Lancet Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 114

The effects of psychosocial stress on dopaminergic function and the acute stress response

Bloomfield, M. A., McCutcheon, R. A., Kempton, M., Freeman, T. P., & Howes, O. (2019) · eLife

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 112

Long-Term Heavy Ketamine Use is Associated with Spatial Memory Impairment and Altered Hippocampal Activation

Morgan, C. J. A., Dodds, C. M., Furby, H., Pepper, F., Fam, J., Freeman, T. P., Hughes, E., Doeller, C., King, J., Howes, O., et al. (2014) · Frontiers in Psychiatry

Memory and Neural MechanismsAnesthesia and Neurotoxicity Research

Cited by 110

Aberrant Salience, Information Processing, and Dopaminergic Signaling in People at Clinical High Risk for Psychosis

Howes, O. D., Hird, E. J., Adams, R. A., Corlett, P. R., & McGuire, P. (2020) · Biological Psychiatry

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 110

Mesolimbic Dopamine Function Is Related to Salience Network Connectivity: An Integrative Positron Emission Tomography and Magnetic Resonance Study

McCutcheon, R. A., Nour, M. M., Dahoun, T., Jauhar, S., Pepper, F., Expert, P., Veronese, M., Adams, R. A., Turkheimer, F., Mehta, M. A., et al. (2019) · Biological Psychiatry

Functional Brain Connectivity StudiesNeurotransmitter Receptor Influence on Behavior

Cited by 104