Turecki, Gustavo

Genome-wide association study reveals two new risk loci for bipolar disorder

Mühleisen, T. W., Leber, M., Schulze, T. G., Strohmaier, J., Degenhardt, F., Treutlein, J., Mattheisen, M., Forstner, A. J., Schumacher, J., Breuer, R., et al. (2014) · Nature Communications

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 346

Differential Glucocorticoid Receptor Exon 1B, 1C, and 1H Expression and Methylation in Suicide Completers with a History of Childhood Abuse

Labonte, B., Yerko, V., Gross, J., Mechawar, N., Meaney, M. J., Szyf, M., & Turecki, G. (2012) · Biological Psychiatry

Stress Responses and CortisolSuicide and Self-Harm Studies

Cited by 345

International Society for Bipolar Disorders Task Force on Suicide: meta‐analyses and meta‐regression of correlates of suicide attempts and suicide deaths in bipolar disorder

Schaffer, A., Isometsä, E. T., Tondo, L., H Moreno, D., Turecki, G., Reis, C., Cassidy, F., Sinyor, M., Azorin, J., Kessing, L. V., et al. (2015) · Bipolar Disorders

Bipolar Disorder and TreatmentSuicide and Self-Harm Studies

Cited by 335

Impulsive-aggressive behaviours and completed suicide across the life cycle: a predisposition for younger age of suicide

McGirr, A., Renaud, J., Bureau, A., Seguin, M., Lesage, A., & Turecki, G. (2008) · Psychological Medicine

Suicide and Self-Harm StudiesHomicide, Infanticide, and Child Abuse

Cited by 332

Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus

Suderman, M., McGowan, P. O., Sasaki, A., Huang, T. C. T., Hallett, M. T., Meaney, M. J., Turecki, G., & Szyf, M. (2012) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationStress Responses and Cortisol

Cited by 327

MicroRNA Expression Is Down-Regulated and Reorganized in Prefrontal Cortex of Depressed Suicide Subjects

Smalheiser, N. R., Lugli, G., Rizavi, H. S., Torvik, V. I., Turecki, G., & Dwivedi, Y. (2012) · PLoS ONE

MicroRNA in disease regulationTreatment of Major Depression

Cited by 324

Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression

Golden, S. A., Christoffel, D. J., Heshmati, M., Hodes, G. E., Magida, J., Davis, K., Cahill, M. E., Dias, C., Ribeiro, E., Ables, J. L., et al. (2013) · Nature Medicine

Treatment of Major DepressionStress Responses and Cortisol

Cited by 322

miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment

Lopez, J. P., Lim, R., Cruceanu, C., Crapper, L., Fasano, C., Labonte, B., Maussion, G., Yang, J. P., Yerko, V., Vigneault, E., et al. (2014) · Nature Medicine

Treatment of Major DepressionMicroRNA in disease regulation

Cited by 308

Astrocytic abnormalities and global DNA methylation patterns in depression and suicide

Nagy, C., Suderman, M., Yang, J., Szyf, M., Mechawar, N., Ernst, C., & Turecki, G. (2015) · Molecular Psychiatry

Epigenetics and DNA MethylationTreatment of Major Depression

Cited by 301

The neurodevelopmental origins of suicidal behavior

Turecki, G., Ernst, C., Jollant, F., Labonté, B., & Mechawar, N. (2012) · Trends in Neurosciences

Suicide and Self-Harm StudiesStress Responses and Cortisol

Cited by 299

Suicide risk assessment and intervention in people with mental illness

Bolton, J. M., Gunnell, D., & Turecki, G. (2015) · BMJ

Suicide and Self-Harm StudiesPsychiatric care and mental health services

Cited by 294

Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression

Klempan, T. A., Sequeira, A., Canetti, L., Lalovic, A., Ernst, C., ffrench-Mullen, J., & Turecki, G. (2009) · Molecular Psychiatry

Suicide and Self-Harm StudiesTreatment of Major Depression

Cited by 294

The molecular bases of the suicidal brain

Turecki, G. (2014) · Nature Reviews Neuroscience

Suicide and Self-Harm StudiesNeurotransmitter Receptor Influence on Behavior

Cited by 281

A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders

Anguelova, M., Benkelfat, C., & Turecki, G. (2003) · Molecular Psychiatry

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 276

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., Power, R. A., Ripke, S., Stahl, E. A., Starnawska, A., et al. (2019) · American Journal of Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 270

BECon: a tool for interpreting DNA methylation findings from blood in the context of brain

Edgar, R. D., Jones, M. J., Meaney, M. J., Turecki, G., & Kobor, M. S. (2017) · Translational Psychiatry

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 261

Intravenous arketamine for treatment-resistant depression: open-label pilot study

Leal, G. C., Bandeira, I. D., Correia-Melo, F. S., Telles, M., Mello, R. P., Vieira, F., Lima, C. S., Jesus-Nunes, A. P., Guerreiro-Costa, L. N. F., Marback, R. F., et al. (2021) · European Archives of Psychiatry and Clinical Neuroscience

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 257

What is the meaning of treatment resistant/refractory major depression (TRD)? A systematic review of current randomized trials

Berlim, M. T., & Turecki, G. (2007) · European Neuropsychopharmacology

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 249

DNA methylation and childhood maltreatment: From animal models to human studies

Lutz, P.-E., & Turecki, G. (2014) · Neuroscience

Child Abuse and TraumaEpigenetics and DNA Methylation

Cited by 236

Alternative Splicing, Methylation State, and Expression Profile of Tropomyosin-Related Kinase B in the Frontal Cortex of Suicide Completers

Ernst, C., Deleva, V., Deng, X., Sequeira, A., Pomarenski, A., Klempan, T., Ernst, N., Quirion, R., Gratton, A., Szyf, M., et al. (2009) · Archives of General Psychiatry

Suicide and Self-Harm StudiesTreatment of Major Depression

Cited by 235

Genome-Wide Methylation Changes in the Brains of Suicide Completers

Labonté, B., Suderman, M., Maussion, G., Lopez, J. P., Navarro-Sánchez, L., Yerko, V., Mechawar, N., Szyf, M., Meaney, M. J., & Turecki, G. (2013) · American Journal of Psychiatry

Epigenetics and DNA MethylationSuicide and Self-Harm Studies

Cited by 212

Association of a history of child abuse with impaired myelination in the anterior cingulate cortex: convergent epigenetic, transcriptional, and morphological evidence

Lutz, P.-E., Tanti, A., Gasecka, A., Barnett-Burns, S., Kim, J. J., Zhou, Y., Chen, G. G., Wakid, M., Shaw, M., Almeida, D., et al. (2017) · American Journal of Psychiatry

Child Abuse and TraumaEpigenetics and DNA Methylation

Cited by 203

MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes

Lopez, J. P., Fiori, L. M., Cruceanu, C., Lin, R., Labonte, B., Cates, H. M., Heller, E. A., Vialou, V., Ku, S. M., Gerald, C., et al. (2017) · Nature Communications

Treatment of Major DepressionMicroRNA in disease regulation

Cited by 201

Efficacy and safety of adjunctive therapy using esketamine or racemic ketamine for adult treatment-resistant depression: A randomized, double-blind, non-inferiority study

Correia-Melo, F. S., Leal, G. C., Vieira, F., Jesus-Nunes, A. P., Mello, R. P., Magnavita, G., Caliman-Fontes, A. T., Echegaray, M. V. F., Bandeira, I. D., Silva, S. S., et al. (2020) · Journal of Affective Disorders

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 193