Herbig, Utz

Telomere Shortening Triggers Senescence of Human Cells through a Pathway Involving ATM, p53, and p21CIP1, but Not p16INK4a

Herbig, U., Jobling, W. A., Chen, B. P. C., Chen, D. J., & Sedivy, J. M. (2004) · Molecular Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,344

Cellular Senescence in Aging Primates

Herbig, U., Ferreira, M., Condel, L., Carey, D., & Sedivy, J. M. (2006) · Science

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,101

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

Fumagalli, M., Rossiello, F., Clerici, M., Barozzi, S., Cittaro, D., Kaplunov, J. M., Bucci, G., Dobreva, M., Matti, V., Beausejour, C. M., et al. (2012) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 851

Accumulation of senescent cells in Mitotic tissue of aging primates

Jeyapalan, J. C., Ferreira, M., Sedivy, J. M., & Herbig, U. (2007) · Mechanisms of Ageing and Development

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 571

Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology

Levy, D., Neuhausen, S. L., Hunt, S. C., Kimura, M., Hwang, S.-J., Chen, W., Bis, J. C., Fitzpatrick, A. L., Smith, E., Johnson, A. D., et al. (2010) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenetic Associations and Epidemiology

Cited by 259

Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells

Benhamed, M., Herbig, U., Ye, T., Dejean, A., & Bischof, O. (2012) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceMicroRNA in disease regulation

Cited by 252

AP-1 imprints a reversible transcriptional programme of senescent cells.

Martínez-Zamudio, R. I., Roux, P.-F., de Freitas, J. A. N. L. F., Robinson, L., Doré, G., Sun, B., Belenki, D., Milanovic, M., Herbig, U., Schmitt, C. A., et al. (2020) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 236

Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions.

Suram, A., Kaplunov, J., Patel, P. L., Ruan, H., Cerutti, A., Boccardi, V., Fumagalli, M., Di Micco, R., Mirani, N., Gurung, R. L., et al. (2012) · The EMBO Journal

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 227

Tracking and fixed ranking of leukocyte telomere length across the adult life course

Benetos, A., Kark, J. D., Susser, E., Kimura, M., Sinnreich, R., Chen, W., Steenstrup, T., Christensen, K., Herbig, U., von Bornemann Hjelmborg, J., et al. (2013) · Aging Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 223

Senescence‐associated β‐galactosidase reveals the abundance of senescent CD8+ T cells in aging humans

Martínez‐Zamudio, R. I., Dewald, H. K., Vasilopoulos, T., Gittens‐Williams, L., Fitzgerald‐Bocarsly, P., & Herbig, U. (2021) · Aging Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 213

Derepression of hTERT gene expression promotes escape from oncogene-induced cellular senescence

Patel, P. L., Suram, A., Mirani, N., Bischof, O., & Herbig, U. (2016) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 142

Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts

Wei, W., Herbig, U., Wei, S., Dutriaux, A., & Sedivy, J. M. (2003) · The EMBO Reports

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 88

Telomere dysfunction promotes transdifferentiation of human fibroblasts into myofibroblasts

Razdan, N., Vasilopoulos, T., & Herbig, U. (2018) · Aging Cell

Telomeres, Telomerase, and SenescenceTGF-β signaling in diseases

Cited by 74

RETRACTED: New intranasal and injectable gene therapy for healthy life extension

Jaijyan, D. K., Selariu, A., Cruz-Cosme, R., Tong, M., Yang, S., Stefa, A., Kekich, D., Sadoshima, J., Herbig, U., Tang, Q., et al. (2022) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchTelomeres, Telomerase, and Senescence

Cited by 57

Age-independent and targetable transcription factor networks regulating CD8+ T cell senescence in aging humans

Turano, P. S., Akbulut, E., Dewald, H. K., Vasilopoulos, T., Fitzgerald-Bocarsly, P., Herbig, U., & Martínez-Zamudio, R. I. (2026) · Cell Reports

T-cell and B-cell ImmunologyTelomeres, Telomerase, and Senescence

Cited by 16