Sarasin, Alain

High expression of DNA repair pathways is associated with metastasis in melanoma patients

Kauffmann, A., Rosselli, F., Lazar, V, Winnepenninckx, V, Mansuet-Lupo, A., Dessen, P., van den Oord, J. J., Spatz, A., & Sarasin, A. (2008) · Oncogene

Cutaneous Melanoma Detection and ManagementDNA Repair Mechanisms

Cited by 274

UV Irradiation Triggers Ubiquitin-Dependent Degradation of p21WAF1 to Promote DNA Repair

Bendjennat, M., Boulaire, J., Jascur, T., Brickner, H., Barbier, V., Sarasin, A., Fotedar, A., & Fotedar, R. (2003) · Cell

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 248

The molecular pathways of ultraviolet-induced carcinogenesis

Sarasin, A. (1999) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

DNA Repair MechanismsSkin Protection and Aging

Cited by 215

XPD Mutations Prevent TFIIH-Dependent Transactivation by Nuclear Receptors and Phosphorylation of RARα

Keriel, A., Stary, A., Sarasin, A., Rochette-Egly, C., & Egly, J.-M. (2002) · Cell

DNA Repair MechanismsNuclear Structure and Function

Cited by 192

The Role of UV Induced Lesions in Skin Carcinogenesis: An Overview of Oncogene and Tumor Suppressor Gene Modifications in Xeroderma Pigmentosum Skin Tumors

Daya-Grosjean, L., & Sarasin, A. (2005) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

DNA Repair MechanismsNonmelanoma Skin Cancer Studies

Cited by 142

CPDs and 6-4PPs play different roles in UV-induced cell death in normal and NER-deficient human cells

Lima-Bessa, K. M. D., Armelini, M. G., Chiganças, V., Jacysyn, J. F., Amarante-Mendes, G. P., Sarasin, A., & Menck, C. F. M. (2008) · DNA Repair

DNA Repair MechanismsSkin Protection and Aging

Cited by 87

Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irradiated human cells

Quinet, A., Martins, D. J., Vessoni, A. T., Biard, D., Sarasin, A., Stary, A., & Menck, C. F. M. (2016) · Nucleic Acids Research

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 76

Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome

Quinet, A., Vessoni, A. T., Rocha, C. R. R., Gottifredi, V., Biard, D., Sarasin, A., Menck, C. F. M., & Stary, A. (2014) · DNA Repair

DNA Repair MechanismsCarcinogens and Genotoxicity Assessment

Cited by 70

Molecular Responses to Photogenotoxic Stress Induced by the Antibiotic Lomefloxacin in Human Skin Cells: From DNA Damage to Apoptosis

Marrot, L., Belaïdi, J. P., Jones, C., Perez, P., Meunier, J. R., Riou, L., & Sarasin, A. (2003) · Journal of Investigative Dermatology

Skin Protection and AgingCarcinogens and Genotoxicity Assessment

Cited by 70

New insights for understanding the transcription-coupled repair pathway

Sarasin, A., & Stary, A. (2007) · DNA Repair

DNA Repair MechanismsNuclear Structure and Function

Cited by 66

Preclinical Corrective Gene Transfer in Xeroderma Pigmentosum Human Skin Stem Cells

Warrick, E., Garcia, M., Chagnoleau, C., Chevallier, O., Bergoglio, V., Sartori, D., Mavilio, F., Angulo, J. F., Avril, M.-F., Sarasin, A., et al. (2012) · Molecular Therapy

Virus-based gene therapy researchDNA Repair Mechanisms

Cited by 58

Predominant role of DNA polymerase eta and p53-dependent translesion synthesis in the survival of ultraviolet-irradiated human cells

Lerner, L. K., Francisco, G., Soltys, D. T., Rocha, C. R. R., Quinet, A., Vessoni, A. T., Castro, L. P., David, T. I. P., Bustos, S. O., Strauss, B. E., et al. (2017) · Nucleic Acids Research

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 53

Novel XPG ( ERCC5 ) Mutations Affect DNA Repair and Cell Survival after Ultraviolet but not Oxidative Stress

Soltys, D. T., Rocha, C. R. R., Lerner, L. K., de Souza, T. A., Munford, V., Cabral, F., Nardo, T., Stefanini, M., Sarasin, A., Cabral‐Neto, J. B., et al. (2013) · Human Mutation

DNA Repair MechanismsGenomics and Rare Diseases

Cited by 48

Differential repair of the two major UV-induced photolesions in trichothiodystrophy fibroblasts

Riou, L., Eveno, E., van Hoffen, A., van Zeeland, A. A., Sarasin, A., & Mullenders, L. H. F. (2004) · Cancer Research

DNA Repair MechanismsNuclear Structure and Function

Cited by 46

UVSSA and USP7: New players regulating transcription-coupled nucleotide excision repair in human cells

Sarasin, A. (2012) · Genome Medicine

DNA Repair MechanismsNuclear Structure and Function

Cited by 34

Characteristics of UV-induced Mutation Spectra in Human XP-D/ERCC2 Gene-mutated Xeroderma Pigmentosum and Trichothiodystrophy Cells

Marionnet, C., Benoit, A., Benhamou, S., Sarasin, A., & Stary, A. (1995) · Journal of Molecular Biology

DNA Repair MechanismsCarcinogens and Genotoxicity Assessment

Cited by 31

Adenovirus mediated transduction of the human DNA polymerase eta cDNA

Lima-Bessa, K. M., Chiganças, V., Stary, A., Kannouche, P., Sarasin, A., Armelini, M. G., de Fátima Jacysyn, J., Amarante-Mendes, G. P., Cordeiro-Stone, M., Cleaver, J. E., et al. (2006) · DNA Repair

DNA Repair MechanismsVirus-based gene therapy research

Cited by 11