Chazin, Walter J.

Metal Chelation and Inhibition of Bacterial Growth in Tissue Abscesses

Corbin, B. D., Seeley, E. H., Raab, A., Feldmann, J., Miller, M. R., Torres, V. J., Anderson, K. L., Dattilo, B. M., Dunman, P. M., Gerads, R., et al. (2008) · Science

S100 Proteins and AnnexinsCalpain Protease Function and Regulation

Cited by 857

Nutrient Metal Sequestration by Calprotectin Inhibits Bacterial Superoxide Defense, Enhancing Neutrophil Killing of Staphylococcus aureus

Kehl-Fie, T. E., Chitayat, S., Hood, M. I., Damo, S., Restrepo, N., Garcia, C., Munro, K. A., Chazin, W. J., & Skaar, E. P. (2011) · Cell Host & Microbe

S100 Proteins and AnnexinsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 419

Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens

Damo, S. M., Kehl-Fie, T. E., Sugitani, N., Holt, M. E., Rathi, S., Murphy, W. J., Zhang, Y., Betz, C., Hench, L., Fritz, G., et al. (2013) · Proceedings of the National Academy of Sciences

S100 Proteins and AnnexinsAntimicrobial Peptides and Activities

Cited by 388

Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases

Pruneda, J. N., Littlefield, P. J., Soss, S. E., Nordquist, K. A., Chazin, W. J., Brzovic, P. S., & Klevit, R. E. (2012) · Molecular Cell

Ubiquitin and proteasome pathwaysEnzyme Structure and Function

Cited by 333

Zinc Sequestration by the Neutrophil Protein Calprotectin Enhances Salmonella Growth in the Inflamed Gut

Liu, J. Z., Jellbauer, S., Poe, A. J., Ton, V., Pesciaroli, M., Kehl-Fie, T. E., Restrepo, N. A., Hosking, M. P., Edwards, R. A., Battistoni, A., et al. (2012) · Cell Host & Microbe

Salmonella and Campylobacter epidemiologyS100 Proteins and Annexins

Cited by 328

Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection

Zackular, J. P., Moore, J. L., Jordan, A. T., Juttukonda, L. J., Noto, M. J., Nicholson, M. R., Crews, J. D., Semler, M. W., Zhang, Y., Ware, L. B., et al. (2016) · Nature Medicine

Clostridium difficile and Clostridium perfringens researchGut microbiota and health

Cited by 275

Identification of an Acinetobacter baumannii Zinc Acquisition System that Facilitates Resistance to Calprotectin-mediated Zinc Sequestration

Hood, M. I., Mortensen, B. L., Moore, J. L., Zhang, Y., Kehl-Fie, T. E., Sugitani, N., Chazin, W. J., Caprioli, R. M., & Skaar, E. P. (2012) · PLoS Pathogens

Bacterial Genetics and BiotechnologyAntibiotic Resistance in Bacteria

Cited by 255

Nutritional immunity: S100 proteins at the host–pathogen interface

Zackular, J. P., Chazin, W. J., & Skaar, E. P. (2015) · Journal of Biological Chemistry

S100 Proteins and AnnexinsAntimicrobial Peptides and Activities

Cited by 235

MntABC and MntH Contribute to Systemic Staphylococcus aureus Infection by Competing with Calprotectin for Nutrient Manganese

Kehl-Fie, T. E., Zhang, Y., Moore, J. L., Farrand, A. J., Hood, M. I., Rathi, S., Chazin, W. J., Caprioli, R. M., & Skaar, E. P. (2013) · Infection and Immunity

Antimicrobial Resistance in StaphylococcusBacterial Genetics and Biotechnology

Cited by 213

Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry

Zhao, W., Vaithiyalingam, S., San Filippo, J., Maranon, D. G., Jimenez-Sainz, J., Fontenay, G. V., Kwon, Y., Leung, S. G., Lu, L., Jensen, R. B., et al. (2015) · Molecular Cell

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 177

Salmonella Mitigates Oxidative Stress and Thrives in the Inflamed Gut by Evading Calprotectin-Mediated Manganese Sequestration

Diaz-Ochoa, V. E., Lam, D., Lee, C. S., Klaus, S., Behnsen, J., Liu, J. Z., Chim, N., Nuccio, S.-P., Rathi, S. G., Mastroianni, J. R., et al. (2016) · Cell Host & Microbe

Salmonella and Campylobacter epidemiologyBacterial Genetics and Biotechnology

Cited by 164

Zinc and Manganese Chelation by Neutrophil S100A8/A9 (Calprotectin) Limits Extracellular Aspergillus fumigatus Hyphal Growth and Corneal Infection

Clark, H. L., Jhingran, A., Sun, Y., Vareechon, C., de Jesus Carrion, S., Skaar, E. P., Chazin, W. J., Calera, J. A., Hohl, T. M., & Pearlman, E. (2016) · The Journal of Immunology

S100 Proteins and AnnexinsAntifungal resistance and susceptibility

Cited by 149

The Response of Acinetobacter baumannii to Zinc Starvation

Nairn, B. L., Lonergan, Z. R., Wang, J., Braymer, J. J., Zhang, Y., Calcutt, M. W., Lisher, J. P., Gilston, B. A., Chazin, W. J., de Crécy-Lagard, V., et al. (2016) · Cell Host & Microbe

Bacterial Genetics and BiotechnologyTrace Elements in Health

Cited by 148

The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction

Wakeman, C. A., Moore, J. L., Noto, M. J., Zhang, Y., Singleton, M. D., Prentice, B. M., Gilston, B. A., Doster, R. S., Gaddy, J. A., Chazin, W. J., et al. (2016) · Nature Communications

Bacterial biofilms and quorum sensingS100 Proteins and Annexins

Cited by 137

XPA: A key scaffold for human nucleotide excision repair

Sugitani, N., Sivley, R. M., Perry, K. E., Capra, J. A., & Chazin, W. J. (2016) · DNA Repair

DNA Repair MechanismsNuclear Structure and Function

Cited by 116

Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis

Weiss, A., Murdoch, C. C., Edmonds, K. A., Jordan, M. R., Monteith, A. J., Perera, Y. R., Rodríguez Nassif, A. M., Petoletti, A. M., Beavers, W. N., Munneke, M. J., et al. (2022) · Cell

Trace Elements in HealthHeavy Metal Exposure and Toxicity

Cited by 113

Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut

Behnsen, J., Zhi, H., Aron, A. T., Subramanian, V., Santus, W., Lee, M. H., Gerner, R. R., Petras, D., Liu, J. Z., Green, K. D., et al. (2021) · Nature Communications

Bacterial Genetics and BiotechnologyEscherichia coli research studies

Cited by 101

Acinetobacter baumannii Response to Host-Mediated Zinc Limitation Requires the Transcriptional Regulator Zur

Mortensen, B. L., Rathi, S., Chazin, W. J., & Skaar, E. P. (2014) · Journal of Bacteriology

Bacterial Genetics and BiotechnologyAntibiotic Resistance in Bacteria

Cited by 94

Zinc Piracy as a Mechanism of Neisseria meningitidis for Evasion of Nutritional Immunity

Stork, M., Grijpstra, J., Bos, M. P., Mañas Torres, C., Devos, N., Poolman, J. T., Chazin, W. J., & Tommassen, J. (2013) · PLoS Pathogens

Bacterial Infections and VaccinesBacterial Genetics and Biotechnology

Cited by 87

The Host Protein Calprotectin Modulates the Helicobacter pylori cag Type IV Secretion System via Zinc Sequestration

Gaddy, J. A., Radin, J. N., Loh, J. T., Piazuelo, M. B., Kehl-Fie, T. E., Delgado, A. G., Ilca, F. T., Peek, R. M., Cover, T. L., Chazin, W. J., et al. (2014) · PLoS Pathogens

Helicobacter pylori-related gastroenterology studiesS100 Proteins and Annexins

Cited by 87

Checkpoint Kinase ATR Promotes Nucleotide Excision Repair of UV-induced DNA Damage via Physical Interaction with Xeroderma Pigmentosum Group A

Shell, S. M., Li, Z., Shkriabai, N., Kvaratskhelia, M., Brosey, C., Serrano, M. A., Chazin, W. J., Musich, P. R., & Zou, Y. (2009) · Journal of Biological Chemistry

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 86

An Acinetobacter baumannii, Zinc-Regulated Peptidase Maintains Cell Wall Integrity during Immune-Mediated Nutrient Sequestration

Lonergan, Z. R., Nairn, B. L., Wang, J., Hsu, Y.-P., Hesse, L. E., Beavers, W. N., Chazin, W. J., Trinidad, J. C., VanNieuwenhze, M. S., Giedroc, D. P., et al. (2019) · Cell Reports

Bacterial Genetics and BiotechnologyAntibiotic Resistance in Bacteria

Cited by 76

Multi-metal restriction by calprotectin impacts de novo flavin biosynthesis in Acinetobacter baumannii

Wang, J., Lonergan, Z. R., Gonzalez-Gutierrez, G., Nairn, B. L., Maxwell, C. N., Zhang, Y., Andreini, C., Karty, J. A., Chazin, W. J., Trinidad, J. C., et al. (2019) · Cell chemical biology

Bacterial Genetics and BiotechnologyBiochemical and Molecular Research

Cited by 76

S100 Proteins in the Innate Immune Response to Pathogens

Kozlyuk, N., Monteith, A. J., Garcia, V., Damo, S. M., Skaar, E. P., & Chazin, W. J. (2019) · Methods in Molecular Biology

S100 Proteins and AnnexinsAntimicrobial Peptides and Activities

Cited by 72