Morris, John A.

An atlas of genetic influences on osteoporosis in humans and mice

23andMe Research Team, Morris, J. A., Kemp, J. P., Youlten, S. E., Laurent, L., Logan, J. G., Chai, R. C., Vulpescu, N. A., Forgetta, V., Kleinman, A., et al. (2019) · Nature Genetics

Bone health and osteoporosis researchGenetic Associations and Epidemiology

Cited by 773

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells

Chen, L., Ge, B., Casale, F. P., Vasquez, L., Kwan, T., Garrido-Martín, D., Watt, S., Yan, Y., Kundu, K., Ecker, S., et al. (2016) · Cell

Genetic Associations and EpidemiologyEpigenetics and DNA Methylation

Cited by 679

Large-Scale Cellular-Resolution Gene Profiling in Human Neocortex Reveals Species-Specific Molecular Signatures

Zeng, H., Shen, E. H., Hohmann, J. G., Oh, S. W., Bernard, A., Royall, J. J., Glattfelder, K. J., Sunkin, S. M., Morris, J. A., Guillozet-Bongaarts, A. L., et al. (2012) · Cell

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 426

Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens

Morris, J. A., Caragine, C., Daniloski, Z., Domingo, J., Barry, T., Lu, L., Davis, K., Ziosi, M., Glinos, D. A., Hao, S., et al. (2023) · Science

Genetic Associations and EpidemiologyCRISPR and Genetic Engineering

Cited by 208

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease

Youlten, S. E., Kemp, J. P., Logan, J. G., Ghirardello, E. J., Sergio, C. M., Dack, M. R. G., Guilfoyle, S. E., Leitch, V. D., Butterfield, N. C., Komla-Ebri, D., et al. (2021) · Nature Communications

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 133

SCEPTRE improves calibration and sensitivity in single-cell CRISPR screen analysis

Barry, T., Wang, X., Morris, J. A., Roeder, K., & Katsevich, E. (2021) · Genome Biology

Single-cell and spatial transcriptomicsCRISPR and Genetic Engineering

Cited by 86

Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq

Wessels, H.-H., Méndez-Mancilla, A., Hao, Y., Papalexi, E., Mauck, W. M., Lu, L., Morris, J. A., Mimitou, E. P., Smibert, P., Sanjana, N. E., et al. (2023) · Nature Methods

CRISPR and Genetic EngineeringSingle-cell and spatial transcriptomics

Cited by 79

Partial demasculinization of several brain regions in adult male (XY) rats with a dysfunctional androgen receptor gene

Morris, J. A., Jordan, C. L., Dugger, B. N., & Breedlove, S. M. (2005) · The Journal of Comparative Neurology

Sexual Differentiation and DisordersGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Cited by 65

Nonlinear transcriptional responses to gradual modulation of transcription factor dosage

Domingo, J., Minaeva, M., Morris, J. A., Ghatan, S., Ziosi, M., Sanjana, N. E., & Lappalainen, T. (2024) · eLife

CRISPR and Genetic EngineeringGenomics and Chromatin Dynamics

Cited by 18

Non-linear transcriptional responses to gradual modulation of transcription factor dosage

Domingo, J., Minaeva, M., Morris, J. A., Ghatan, S., Ziosi, M., Sanjana, N. E., & Lappalainen, T. (2024) · eLife

Genomics and Chromatin DynamicsCRISPR and Genetic Engineering

Cited by 6