Nagatsu, Toshiharu

Tumor necrosis factor-α (TNF-α) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

Mogi, M., Harada, M., Riederer, P., Narabayashi, H., Fujita, K., & Nagatsu, T. (1994) · Neuroscience Letters

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 986

Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients

Mogi, M., Harada, M., Kondo, T., Riederer, P., Inagaki, H., Minami, M., & Nagatsu, T. (1994) · Neuroscience Letters

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 855

Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains

Imamura, K., Hishikawa, N., Sawada, M., Nagatsu, T., Yoshida, M., & Hashizume, Y. (2003) · Acta Neuropathologica

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 791

Interleukin (IL)-1β, IL-2, IL-4, IL-6 and transforming growth factor-α levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease

Mogi, M., Harada, M., Narabayashi, H., Inagaki, H., Minami, M., & Nagatsu, T. (1996) · Neuroscience Letters

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 545

Role of cytokines in inflammatory process in Parkinson’s disease

Sawada, M., Imamura, K., & Nagatsu, T. (2006) · Parkinson’s Disease and Related Disorders

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 331

A link between stress and depression: Shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression

Miura, H., Ozaki, N., Sawada, M., Isobe, K., Ohta, T., & Nagatsu, T. (2008) · Stress

Tryptophan and brain disordersTreatment of Major Depression

Cited by 282

Quantification of mRNA of tyrosine hydroxylase and aromatic L-amino acid decarboxylase in the substantia nigra in Parkinson’s disease and schizophrenia

Ichinose, H., Ohye, T., Fujita, K., Pantucek, F., Lange, K., Riederer, P., & Nagatsu, T. (1994) · Journal of Neural Transmission - Parkinson's Disease and Dementia Section

Parkinson's Disease Mechanisms and TreatmentsNeurotransmitter Receptor Influence on Behavior

Cited by 107

Homospecific activity (activity per enzyme protein) of tyrosine hydroxylase increases in parkinsonian brain

Mogi, M., Harada, M., Kiuchi, K., Kojima, K., Kondo, T., Narabayashi, H., Rausch, D., Riederer, P., Jellinger, K., & Nagatsu, T. (1988) · Journal of Neural Transmission

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 101

IMMUNOFLUORESCENT STUDIES ON THE LOCALIZATION OF TYROSINE HYDROXYLASE AND DOPAMINE-β-HYDROXYLASE IN THE MES-, DI-, AND TELENCEPHALON OF THE RAT USING UNPERFUSED FRESH FROZEN SECTIONS

NAGATSU, I., INAGAKI, S., KONDO, Y., KARASAWA, N., & NAGATSU, T. (1979) · ACTA HISTOCHEMICA ET CYTOCHEMICA

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 98

Phosphorylation of the N-terminal portion of tyrosine hydroxylase triggers proteasomal digestion of the enzyme

Nakashima, A., Mori, K., Kaneko, Y. S., Hayashi, N., Nagatsu, T., & Ota, A. (2011) · Biochemical and Biophysical Research Communications

Ubiquitin and proteasome pathwaysParkinson's Disease Mechanisms and Treatments

Cited by 52

Parkinson’s Disease: Cells Succumbing to Lifelong Dopamine-Related Oxidative Stress and Other Bioenergetic Challenges

Watanabe, H., Dijkstra, J. M., & Nagatsu, T. (2024) · International Journal of Molecular Sciences

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 48

Inhibition of deubiquitinating activity of USP14 decreases tyrosine hydroxylase phosphorylated at Ser19 in PC12D cells

Nakashima, A., Ohnuma, S., Kodani, Y., Kaneko, Y. S., Nagasaki, H., Nagatsu, T., & Ota, A. (2016) · Biochemical and Biophysical Research Communications

Ubiquitin and proteasome pathwaysParkinson's Disease Mechanisms and Treatments

Cited by 22

Hypothesis: neural mechanism of psychotherapy for the treatment of Parkinson’s disease: cognitive behavioral therapy (CBT), acceptance and commitment therapy (ACT), and Morita therapy?

Nagatsu, T. (2020) · Journal of Neural Transmission

Mindfulness and Compassion InterventionsAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 8