Wohlschlegel, James A.

ProLuCID: An improved SEQUEST-like algorithm with enhanced sensitivity and specificity

Xu, T., Park, S. K., Venable, J. D., Wohlschlegel, J. A., Diedrich, J. K., Cociorva, D., Lu, B., Liao, L., Hewel, J., Han, X., et al. (2015) · Journal of Proteomics

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 511

Control of iron homeostasis by an iron-regulated ubiquitin ligase

Vashisht, A. A., Zumbrennen, K. B., Huang, X., Powers, D. N., Durazo, A., Sun, D., Bhaskaran, N., Persson, A., Uhlen, M., Sangfelt, O., et al. (2009) · Science

Iron Metabolism and DisordersUbiquitin and proteasome pathways

Cited by 429

Human-specific transcriptional regulation of CNS development genes by FOXP2

Konopka, G., Bomar, J. M., Winden, K., Coppola, G., Jonsson, Z. O., Gao, F., Peng, S., Preuss, T. M., Wohlschlegel, J. A., & Geschwind, D. H. (2009) · Nature

Genetics and Neurodevelopmental DisordersLanguage and cultural evolution

Cited by 390

The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1

Machida, Y. J., Machida, Y., Vashisht, A. A., Wohlschlegel, J. A., & Dutta, A. (2009) · Journal of Biological Chemistry

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 274

Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu

Ho, C.-M., Li, X., Lai, M., Terwilliger, T. C., Beck, J. R., Wohlschlegel, J., Goldberg, D. E., Fitzpatrick, A. W. P., & Zhou, Z. H. (2020) · Nature Methods

Advanced Electron Microscopy Techniques and ApplicationsEnzyme Structure and Function

Cited by 115

FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

Shen, J. Z., Qiu, Z., Wu, Q., Finlay, D., Garcia, G., Sun, D., Rantala, J., Barshop, W., Hope, J. L., Gimple, R. C., et al. (2021) · Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 113

JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse

Berg, J. M., Lee, C., Chen, L., Galvan, L., Cepeda, C., Chen, J. Y., Peñagarikano, O., Stein, J. L., Li, A., Oguro-Ando, A., et al. (2015) · Neuron

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 45

An oxygen-dependent interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis

Mayank, A. K., Pandey, V., Vashisht, A. A., Barshop, W. D., Rayatpisheh, S., Sharma, T., Haque, T., Powers, D. N., & Wohlschlegel, J. A. (2019) · Molecular Cell

Iron Metabolism and DisordersUbiquitin and proteasome pathways

Cited by 45

Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome

Sanfilippo, P., Kim, A. J., Bhukel, A., Yoo, J., Mirshahidi, P. S., Pandey, V., Bevir, H., Yuen, A., Mirshahidi, P. S., Guo, P., et al. (2024) · Neuron

Neuroscience and Neuropharmacology ResearchNeurobiology and Insect Physiology Research

Cited by 36

Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome

Sanfilippo, P., Kim, A. J., Bhukel, A., Yoo, J., Mirshahidi, P. S., Pandey, V., Bevir, H., Yuen, A., Mirshahidi, P. S., Guo, P., et al. (2023) · Neuron

Neuroscience and Neuropharmacology ResearchNeurobiology and Insect Physiology Research

Cited by 36

Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal

Zinovyeva, A. Y., Veksler-Lublinsky, I., Vashisht, A. A., Wohlschlegel, J. A., & Ambros, V. R. (2015) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationRNA Interference and Gene Delivery

Cited by 29

ACD15, ACD21 and SLN regulate accumulation and mobility of MBD6 to silence genes and transposable elements

Boone, B. A., Ichino, L., Wang, S., Gardiner, J., Yun, J., Jami-Alahmadi, Y., Sha, J., Mendoza, C. P., Steelman, B. J., van Aardenne, A., et al. (2023) · Science Advances

Epigenetics and DNA MethylationPlant Molecular Biology Research

Cited by 21

Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection

Zhang, T., Li, Y., Pan, L., Sha, J., Bailey, M., Faure-Kumar, E., Williams, C. K., Wohlschlegel, J., Magaki, S., Niu, C., et al. (2024) · Nature Aging

Long-Term Effects of COVID-19SARS-CoV-2 and COVID-19 Research

Cited by 20

FAP106 is an interaction hub for assembling microtubule inner proteins at the cilium inner junction

Shimogawa, M. M., Wijono, A. S., Wang, H., Zhang, J., Sha, J., Szombathy, N., Vadakkan, S., Pelayo, P., Jonnalagadda, K., Wohlschlegel, J., et al. (2023) · Nature Communications

Genetic and Kidney Cyst DiseasesTrypanosoma species research and implications

Cited by 18

MOTS-c modulates skeletal muscle function by directly binding and activating CK2

Kumagai, H., Kim, S.-J., Miller, B., Zempo, H., Tanisawa, K., Natsume, T., Lee, S. H., Wan, J., Leelaprachakul, N., Kumagai, M. E., et al. (2024) · iScience

Muscle Physiology and DisordersMitochondrial Function and Pathology

Cited by 15

CLSY docking to Pol IV requires a conserved domain critical for small RNA biogenesis and transposon silencing

Felgines, L., Rymen, B., Martins, L. M., Xu, G., Matteoli, C., Himber, C., Zhou, M., Eis, J., Coruh, C., Böhrer, M., et al. (2023) · Nature Communications

Chromosomal and Genetic VariationsPlant Molecular Biology Research

Cited by 13

Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis

Blackwell, A. M., Jami-Alahmadi, Y., Nasamu, A. S., Kudo, S., Senoo, A., Slam, C., Tsumoto, K., Wohlschlegel, J. A., Caaveiro, J. M. M., Goldberg, D. E., et al. (2024) · eLife

Malaria Research and ControlHeme Oxygenase-1 and Carbon Monoxide

Cited by 5

Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis

Blackwell, A. M., Jami-Alahmadi, Y., Nasamu, A. S., Kudo, S., Senoo, A., Slam, C., Tsumoto, K., Wohlschlegel, J. A., Manuel Martinez Caaveiro, J., Goldberg, D. E., et al. (2024) · eLife

Malaria Research and ControlHeme Oxygenase-1 and Carbon Monoxide

Cited by 5