Kang, Ho Chul

Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)

Wang, Y., Kim, N. S., Haince, J.-F., Kang, H. C., David, K. K., Andrabi, S. A., Poirier, G. G., Dawson, V. L., & Dawson, T. M. (2011) · Science Signaling

Cell death mechanisms and regulationPARP inhibition in cancer therapy

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Ribosomal Protein s15 Phosphorylation Mediates LRRK2 Neurodegeneration in Parkinson’s Disease

Martin, I., Kim, J. W., Lee, B. D., Kang, H. C., Xu, J.-C., Jia, H., Stankowski, J., Kim, M.-S., Zhong, J., Kumar, M., et al. (2014) · Cell

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

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Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death

Andrabi, S. A., Kang, H. C., Haince, J.-F., Lee, Y.-I., Zhang, J., Chi, Z., West, A. B., Koehler, R. C., Poirier, G. G., Dawson, T. M., et al. (2011) · Nature Medicine

Cell death mechanisms and regulationPARP inhibition in cancer therapy

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Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss

Lee, Y., Karuppagounder, S. S., Shin, J.-H., Lee, Y.-I., Ko, H. S., Swing, D., Jiang, H., Kang, S.-U., Lee, B. D., Kang, H. C., et al. (2013) · Nature Neuroscience

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

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LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase

Choi, I., Kim, B., Byun, J.-W., Baik, S. H., Huh, Y. H., Kim, J.-H., Mook-Jung, I., Song, W. K., Shin, J.-H., Seo, H., et al. (2015) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

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