Brandner, Sebastian

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

Skibinski, G., Parkinson, N. J., Brown, J. M., Chakrabarti, L., Lloyd, S. L., Hummerich, H., Nielsen, J. E., Hodges, J. R., Spillantini, M. G., Thusgaard, T., et al. (2005) · Nature Genetics

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 822

The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study

Charidimou, A., Boulouis, G., Frosch, M. P., Baron, J.-C., Pasi, M., Albucher, J. F., Banerjee, G., Barbato, C., Bonneville, F., Brandner, S., et al. (2022) · The Lancet Neurology

Intracerebral and Subarachnoid Hemorrhage ResearchCerebrovascular and genetic disorders

Cited by 723

Amyloid β oligomers constrict human capillaries in Alzheimer's disease via signaling to pericytes

Nortley, R., Korte, N., Izquierdo, P., Hirunpattarasilp, C., Mishra, A., Jaunmuktane, Z., Kyrargyri, V., Pfeiffer, T., Khennouf, L., Madry, C., et al. (2019) · Science

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 682

Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy

Jaunmuktane, Z., Mead, S., Ellis, M., Wadsworth, J. D. F., Nicoll, A. J., Kenny, J., Launchbury, F., Linehan, J., Richard-Loendt, A., Walker, A. S., et al. (2015) · Nature

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 518

An Aneuploid Mouse Strain Carrying Human Chromosome 21 with down Syndrome Phenotypes.

O'Doherty, A., Ruf, S., Mulligan, C., Hildreth, V., Errington, M. L., Cooke, S., Sesay, A., Modino, S., Vanes, L., Hernandez, D., et al. (2005) · Science

Down syndrome and intellectual disability researchGenomic variations and chromosomal abnormalities

Cited by 434

H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas

Pathania, M., De Jay, N., Maestro, N., Harutyunyan, A. S., Nitarska, J., Pahlavan, P., Henderson, S., Mikael, L. G., Richard-Londt, A., Zhang, Y., et al. (2017) · Cancer Cell

Glioma Diagnosis and TreatmentChromatin Remodeling and Cancer

Cited by 264

Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes

Jacques, T. S., Swales, A., Brzozowski, M. J., Henriquez, N. V., Linehan, J. M., Mirzadeh, Z., O' Malley, C., Naumann, H., Alvarez‐Buylla, A., & Brandner, S. (2010) · The EMBO Journal

Glioma Diagnosis and TreatmentNeurogenesis and neuroplasticity mechanisms

Cited by 214

Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone

Purro, S. A., Farrow, M. A., Linehan, J., Nazari, T., Thomas, D. X., Chen, Z., Mengel, D., Saito, T., Saido, T., Rudge, P., et al. (2018) · Nature

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 191

Extracting structured information from unstructured histopathology reports using generative pre‐trained transformer 4 ( GPT ‐4)

Truhn, D., Loeffler, C. M., Müller‐Franzes, G., Nebelung, S., Hewitt, K. J., Brandner, S., Bressem, K. K., Foersch, S., & Kather, J. N. (2024) · The Journal of Pathology

Artificial Intelligence in Healthcare and EducationAI in cancer detection

Cited by 124

Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice

Ghazi-Noori, S., Froud, K. E., Mizielinska, S., Powell, C., Smidak, M., Fernandez de Marco, M., O’Malley, C., Farmer, M., Parkinson, N., Fisher, E. M. C., et al. (2012) · Brain

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 115

A clinical study of kuru patients with long incubation periods at the end of the epidemic in Papua New Guinea

Collinge, J., Whitfield, J., McKintosh, E., Frosh, A., Mead, S., Hill, A. F., Brandner, S., Thomas, D., & Alpers, M. P. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences

Prion Diseases and Protein MisfoldingAmyloidosis: Diagnosis, Treatment, Outcomes

Cited by 110

Peripheral Administration of a Humanized Anti-PrP Antibody Blocks Alzheimer's Disease Aβ Synaptotoxicity

Klyubin, I., Nicoll, A. J., Khalili-Shirazi, A., Farmer, M., Canning, S., Mably, A., Linehan, J., Brown, A., Wakeling, M., Brandner, S., et al. (2014) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 74

c-Jun expression in human neuropathies: a pilot study

Hutton, E. J., Carty, L., Laurá, M., Houlden, H., Lunn, M. P. T., Brandner, S., Mirsky, R., Jessen, K., & Reilly, M. M. (2011) · Journal of the Peripheral Nervous System

Nerve injury and regenerationPeripheral Neuropathies and Disorders

Cited by 63

Mutation in FAM134B causing severe hereditary sensory neuropathy: Figure 1

Murphy, S. M., Davidson, G. L., Brandner, S., Houlden, H., & Reilly, M. M. (2012) · Journal of Neurology, Neurosurgery & Psychiatry

Hereditary Neurological DisordersGenetic Neurodegenerative Diseases

Cited by 62

Large language models as a diagnostic support tool in neuropathology

Hewitt, K. J., Wiest, I. C., Carrero, Z. I., Bejan, L., Millner, T. O., Brandner, S., & Kather, J. N. (2024) · The Journal of Pathology: Clinical Research

Artificial Intelligence in Healthcare and EducationMachine Learning in Healthcare

Cited by 27

Pharmacological removal of serum amyloid P component from intracerebral plaques and cerebrovascular Aβ amyloid deposits in vivo

Al-Shawi, R., Tennent, G. A., Millar, D. J., Richard-Londt, A., Brandner, S., Werring, D. J., Simons, J. P., & Pepys, M. B. (2016) · Open Biology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 26