Perlin, David S.

The global problem of antifungal resistance: prevalence, mechanisms, and management

Perlin, D. S., Rautemaa-Richardson, R., & Alastruey-Izquierdo, A. (2017) · The Lancet Infectious Diseases

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 1,055

Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory Concentrations

Alexander, B. D., Johnson, M. D., Pfeiffer, C. D., Jiménez-Ortigosa, C., Catania, J., Booker, R., Castanheira, M., Messer, S. A., Perlin, D. S., & Pfaller, M. A. (2013) · Clinical Infectious Diseases

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 778

Frequency and Evolution of Azole Resistance in Aspergillus fumigatus Associated with Treatment Failure1

Howard, S. J., Cerar, D., Anderson, M. J., Albarrag, A., Fisher, M. C., Pasqualotto, A. C., Laverdiere, M., Arendrup, M. C., Perlin, D. S., & Denning, D. W. (2009) · Emerging Infectious Diseases

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 750

Mechanisms of Antifungal Drug Resistance

Cowen, L. E., Sanglard, D., Howard, S. J., Rogers, P. D., & Perlin, D. S. (2015) · Cold Spring Harbor Perspectives in Medicine

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 647

A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance

Chowdhary, A., Prakash, A., Sharma, C., Kordalewska, M., Kumar, A., Sarma, S., Tarai, B., Singh, A., Upadhyaya, G., Upadhyay, S., et al. (2018) · Journal of Antimicrobial Chemotherapy

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 577

Resistance to echinocandin-class antifungal drugs.

Perlin, D. S. (2007) · Drug Resistance Updates

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 512

Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical Candida sp. Isolates

Park, S., Kelly, R., Kahn, J. N., Robles, J., Hsu, M.-J., Register, E., Li, W., Vyas, V., Fan, H., Abruzzo, G., et al. (2005) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 434

Echinocandin resistance in Candida.

Perlin, D. S. (2015) · Clinical Infectious Diseases

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 374

Effect of Candida glabrata FKS1 and FKS2 Mutations on Echinocandin Sensitivity and Kinetics of 1,3-β- d -Glucan Synthase: Implication for the Existing Susceptibility Breakpoint

Garcia-Effron, G., Lee, S., Park, S., Cleary, J. D., & Perlin, D. S. (2009) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 323

A Naturally Occurring Proline-to-Alanine Amino Acid Change in Fks1p in Candida parapsilosis , Candida orthopsilosis , and Candida metapsilosis Accounts for Reduced Echinocandin Susceptibility

Garcia-Effron, G., Katiyar, S. K., Park, S., Edlind, T. D., & Perlin, D. S. (2008) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 323

High-frequency Triazole Resistance Found In Nonculturable Aspergillus fumigatus from Lungs of Patients with Chronic Fungal Disease

Denning, D. W., Park, S., Lass-Florl, C., Fraczek, M. G., Kirwan, M., Gore, R., Smith, J., Bueid, A., Moore, C. B., Bowyer, P., et al. (2011) · Clinical Infectious Diseases

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 313

Mechanisms of echinocandin antifungal drug resistance

Perlin, D. S. (2015) · Annals of the New York Academy of Sciences

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 313

Echinocandin resistance: an emerging clinical problem?

Arendrup, M. C., & Perlin, D. S. (2014) · Current Opinion in Infectious Diseases

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 299

Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance.

Healey, K. R., Zhao, Y., Perez, W. B., Lockhart, S. R., Sobel, J. D., Farmakiotis, D., Kontoyiannis, D. P., Sanglard, D., Taj-Aldeen, S. J., Alexander, B. D., et al. (2016) · Nature Communications

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 276

Current Perspectives on Echinocandin Class Drugs

Perlin, D. S. (2011) · Future Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 274

Correlating Echinocandin MIC and Kinetic Inhibition of fks1 Mutant Glucan Synthases for Candida albicans : Implications for Interpretive Breakpoints

Garcia-Effron, G., Park, S., & Perlin, D. S. (2009) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 256

Understanding Echinocandin Resistance in the Emerging Pathogen Candida auris

Kordalewska, M., Lee, A., Park, S., Berrio, I., Chowdhary, A., Zhao, Y., & Perlin, D. S. (2018) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 247

Assessing Resistance to the Echinocandin Antifungal Drug Caspofungin in Candida albicans by Profiling Mutations in FKS1

Balashov, S. V., Park, S., & Perlin, D. S. (2006) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 225

Requirement for Ergosterol in V-ATPase Function Underlies Antifungal Activity of Azole Drugs

Zhang, Y.-Q., Gamarra, S., Garcia-Effron, G., Park, S., Perlin, D. S., & Rao, R. (2010) · PLoS Pathogens

Antifungal resistance and susceptibilityATP Synthase and ATPases Research

Cited by 206

Breakthrough invasive candidiasis in patients on micafungin.

Pfeiffer, C. D., Garcia-Effron, G., Zaas, A. K., Perfect, J. R., Perlin, D. S., & Alexander, B. D. (2010) · Journal of Clinical Microbiology

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 196

Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrata

Healey, K. R., & Perlin, D. S. (2018) · Journal of Fungi

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 194

Fungal resistance to echinocandins and the MDR phenomenon in Candida glabrata

Healey, K., & Perlin, D. S. (2018) · Journal of Fungi

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 194

Calcineurin Target CrzA Regulates Conidial Germination, Hyphal Growth, and Pathogenesis of Aspergillus fumigatus

Cramer, R. A., Perfect, B. Z., Pinchai, N., Park, S., Perlin, D. S., Asfaw, Y. G., Heitman, J., Perfect, J. R., & Steinbach, W. J. (2008) · Eukaryotic Cell

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 172

Limited ERG11 Mutations Identified in Isolates of Candida auris Directly Contribute to Reduced Azole Susceptibility

Healey, K. R., Kordalewska, M., Jiménez Ortigosa, C., Singh, A., Berrío, I., Chowdhary, A., & Perlin, D. S. (2018) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 165