Perlin, David S.

Fitness and virulence costs of Candida albicans FKS1 hot spot mutations associated with echinocandin resistance.

Ben-Ami, R., Garcia-Effron, G., Lewis, R. E., Gamarra, S., Leventakos, K., Perlin, D. S., & Kontoyiannis, D. P. (2011) · The Journal of Infectious Diseases

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 162

Echinocandin Susceptibility Testing of Candida Species: Comparison of EUCAST EDef 7.1, CLSI M27-A3, Etest, Disk Diffusion, and Agar Dilution Methods with RPMI and IsoSensitest Media

Arendrup, M. C., Garcia-Effron, G., Lass-Flörl, C., Lopez, A. G., Rodriguez-Tudela, J.-L., Cuenca-Estrella, M., & Perlin, D. S. (2010) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityBacterial Identification and Susceptibility Testing

Cited by 158

Efficacy of oral cochleate-amphotericin B in a mouse model of systemic candidiasis

Santangelo, R., Paderu, P., Delmas, G., Chen, Z.-W., Mannino, R., Zarif, L., & Perlin, D. S. (2000) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityAdvanced Drug Delivery Systems

Cited by 150

Fks1 and Fks2 Are Functionally Redundant but Differentially Regulated in Candida glabrata: Implications for Echinocandin Resistance

Katiyar, S. K., Alastruey-Izquierdo, A., Healey, K. R., Johnson, M. E., Perlin, D. S., & Edlind, T. D. (2012) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 148

The Quiet and Underappreciated Rise of Drug-Resistant Invasive Fungal Pathogens

Arastehfar, A., Lass-Flörl, C., Garcia-Rubio, R., Daneshnia, F., Ilkit, M., Boekhout, T., Gabaldon, T., & Perlin, D. S. (2020) · Journal of Fungi

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 145

A Ser678Pro Substitution in Fks1p Confers Resistance to Echinocandin Drugs in Aspergillus fumigatus

Rocha, E. M. F., Garcia-Effron, G., Park, S., & Perlin, D. S. (2007) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 141

Molecular mechanisms of cryptococcal meningitis

Liu, T.-B., Perlin, D. S., & Xue, C. (2012) · Virulence

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 131

Rapid antifungal susceptibility testing by matrix-assisted laser desorption ionization-time of flight mass spectrometry analysis.

Vella, A., De Carolis, E., Vaccaro, L., Posteraro, P., Perlin, D. S., Kostrzewa, M., Posteraro, B., & Sanguinetti, M. (2013) · Journal of Clinical Microbiology

Bacterial Identification and Susceptibility TestingAntifungal resistance and susceptibility

Cited by 124

Antifungal Activity of Amphotericin B Cochleates against Candida albicans Infection in a Mouse Model

Zarif, L., Graybill, J. R., Perlin, D., Najvar, L., Bocanegra, R., & Mannino, R. J. (2000) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityNanoparticle-Based Drug Delivery

Cited by 122

Reduced Candida glabrata Susceptibility Secondary to an FKS1 Mutation Developed during Candidemia Treatment

Cleary, J. D., Garcia-Effron, G., Chapman, S. W., & Perlin, D. S. (2008) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 118

Acquired Echinocandin Resistance in a Candida krusei Isolate Due to Modification of Glucan Synthase

Kahn, J. N., Garcia-Effron, G., Hsu, M.-J., Park, S., Marr, K. A., & Perlin, D. S. (2007) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 118

Differential In Vivo Activities of Anidulafungin, Caspofungin, and Micafungin against Candida glabrata Isolates with and without FKS Resistance Mutations

Arendrup, M. C., Perlin, D. S., Jensen, R. H., Howard, S. J., Goodwin, J., & Hope, W. (2012) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 117

Unraveling drug penetration of echinocandin antifungals at the site of infection in an intra-abdominal abscess model

Zhao, Y., Prideaux, B., Nagasaki, Y., Lee, M. H., Chen, P.-Y., Blanc, L., Ho, H., Clancy, C. J., Nguyen, M. H., Dartois, V., et al. (2017) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityAntibiotics Pharmacokinetics and Efficacy

Cited by 102

Echinocandin Resistance, Susceptibility Testing and Prophylaxis: Implications for Patient Management

Perlin, D. S. (2014) · Drugs

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 99

Stepwise emergence of azole, echinocandin and amphotericin B multidrug resistance in vivo in Candida albicans orchestrated by multiple genetic alterations

Jensen, R. H., Astvad, K. M. T., Silva, L. V., Sanglard, D., Jørgensen, R., Nielsen, K. F., Mathiasen, E. G., Doroudian, G., Perlin, D. S., & Arendrup, M. C. (2015) · Journal of Antimicrobial Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 95

Genetic Drivers of Multidrug Resistance in Candida glabrata

Healey, K. R., Jimenez Ortigosa, C., Shor, E., & Perlin, D. S. (2016) · Frontiers in Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 93

De Novo Acquisition of Resistance to SCY-078 in Candida glabrata Involves FKS Mutations That both Overlap and Are Distinct from Those Conferring Echinocandin Resistance

Jiménez-Ortigosa, C., Perez, W. B., Angulo, D., Borroto-Esoda, K., & Perlin, D. S. (2017) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 89

Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in Cryptococcus neoformans

Huang, W., Liao, G., Baker, G. M., Wang, Y., Lau, R., Paderu, P., Perlin, D. S., & Xue, C. (2016) · mBio

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 88

Tolerance to Caspofungin in Candida albicans Is Associated with at Least Three Distinctive Mechanisms That Govern Expression of FKS Genes and Cell Wall Remodeling

Yang, F., Zhang, L., Wakabayashi, H., Myers, J., Jiang, Y., Cao, Y., Jimenez-Ortigosa, C., Perlin, D. S., & Rustchenko, E. (2017) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 81

CD101: a novel long-acting echinocandin

Zhao, Y., Perez, W. B., Jiménez‐Ortigosa, C., Hough, G., Locke, J. B., Ong, V., Bartizal, K., & Perlin, D. S. (2016) · Cellular Microbiology

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 81

Fluconazole and Echinocandin resistance of Candida glabrata correlates better with antifungal drug exposure rather than with MSH2 mutator genotype in a French Cohort of patients harboring low rates of resistance.

Dellière, S., Healey, K., Gits-Muselli, M., Carrara, B., Barbaro, A., Guigue, N., Lecefel, C., Touratier, S., Desnos-Ollivier, M., Perlin, D. S., et al. (2016) · Frontiers in Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 75

Emergence of Echinocandin Resistance Due to a Point Mutation in the fks1 Gene of Aspergillus fumigatus in a Patient with Chronic Pulmonary Aspergillosis

Jiménez-Ortigosa, C., Moore, C., Denning, D. W., & Perlin, D. S. (2017) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 72

Mechanism of the Synergistic Effect of Amiodarone and Fluconazole in Candida albicans

Gamarra, S., Rocha, E. M. F., Zhang, Y.-Q., Park, S., Rao, R., & Perlin, D. S. (2010) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 70

Echovirus 30, Jiangsu Province, China

Zhao, Y. N., Jiang, Q. W., Jiang, R. J., Chen, L., & Perlin, D. S. (2005) · Emerging infectious diseases

Viral Infections and Immunology ResearchInfectious Encephalopathies and Encephalitis

Cited by 68