Park, B. Kevin

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Bell, C. C., Hendriks, D. F. G., Moro, S. M. L., Ellis, E., Walsh, J., Renblom, A., Fredriksson Puigvert, L., Dankers, A. C. A., Jacobs, F., Snoeys, J., et al. (2016) · Scientific Reports

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 739

Role of Drug Disposition in Drug Hypersensitivity: A Chemical, Molecular, and Clinical Perspective

Park, B. K., Pirmohamed, M., & Kitteringham, N. R. (1998) · Chemical Research in Toxicology

Drug-Induced Adverse ReactionsPharmacogenetics and Drug Metabolism

Cited by 267

Assessing the Safety of Stem Cell Therapeutics

Goldring, C. E. P., Duffy, P. A., Benvenisty, N., Andrews, P. W., Ben-David, U., Eakins, R., French, N., Hanley, N. A., Kelly, L., Kitteringham, N. R., et al. (2011) · Cell Stem Cell

Biomedical Ethics and RegulationPluripotent Stem Cells Research

Cited by 245

Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity—Implications for therapeutic targeting of Nrf2

Olayanju, A., Copple, I. M., Bryan, H. K., Edge, G. T., Sison, R. L., Wong, M. W., Lai, Z.-Q., Lin, Z.-X., Dunn, K., Sanderson, C. M., et al. (2015) · Free Radical Biology and Medicine

Genomics, phytochemicals, and oxidative stressBioactive Compounds and Antitumor Agents

Cited by 232

Alternatively activated macrophages promote resolution of necrosis following acute liver injury

Starkey Lewis, P., Campana, L., Aleksieva, N., Cartwright, J. A., Mackinnon, A., O'Duibhir, E., Kendall, T., Vermeren, M., Thomson, A., Gadd, V., et al. (2020) · Journal of Hepatology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 209

The utility of HepG2 cells to identify direct mitochondrial dysfunction in the absence of cell death

Kamalian, L., Chadwick, A. E., Bayliss, M., French, N. S., Monshouwer, M., Snoeys, J., & Park, B. K. (2015) · Toxicology in Vitro

Drug-Induced Hepatotoxicity and ProtectionMitochondrial Function and Pathology

Cited by 160

Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation

Lauschke, V. M., Vorrink, S. U., Moro, S. M. L., Rezayee, F., Nordling, Å., Hendriks, D. F. G., Bell, C. C., Sison‐Young, R., Park, B. K., Goldring, C. E., et al. (2016) · Hepatology

Liver physiology and pathologyMicroRNA in disease regulation

Cited by 121

The effect of genetic polymorphisms in CYP2C9 on sulphamethoxazole N-hydroxylation

Gill, H. J., Tjia, J. F., Kitteringham, N. R., Pirmohamed, M., Back, D. J., & Park, B. K. (1999) · Pharmacogenetics

Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection

Cited by 48

Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolites

Sanderson, J. P., Hollis, F. J., Maggs, J. L., Clarke, S. E., Naisbitt, D. J., & Park, B. K. (2008) · Drug Metabolism and Disposition

Pharmacogenetics and Drug MetabolismDrug-Induced Adverse Reactions

Cited by 8