Almo, Steven C.

A metabolic pathway for bile acid dehydroxylation by the gut microbiome

Funabashi, M., Grove, T. L., Wang, M., Varma, Y., McFadden, M. E., Brown, L. C., Guo, C., Higginbottom, S., Almo, S. C., & Fischbach, M. A. (2020) · Nature

Steroid Chemistry and BiochemistryMicrobial Natural Products and Biosynthesis

Cited by 590

GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells

Smith, E. L., Harrington, K., Staehr, M., Masakayan, R., Jones, J., Long, T. J., Ng, K. Y., Ghoddusi, M., Purdon, T. J., Wang, X., et al. (2019) · Science Translational Medicine

CAR-T cell therapy researchMultiple Myeloma Research and Treatments

Cited by 391

Durable antitumor responses to CD47 blockade require adaptive immune stimulation

Sockolosky, J. T., Dougan, M., Ingram, J. R., Ho, C. C. M., Kauke, M. J., Almo, S. C., Ploegh, H. L., & Garcia, K. C. (2016) · Proceedings of the National Academy of Sciences

Phagocytosis and Immune RegulationCancer Immunotherapy and Biomarkers

Cited by 366

Recent advances in mammalian protein production

Bandaranayake, A. D., & Almo, S. C. (2014) · FEBS Letters

Viral Infectious Diseases and Gene Expression in InsectsProtein purification and stability

Cited by 222

Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin

Metcalf, B., Chuang, C., Dufu, K., Patel, M. P., Silva-Garcia, A., Johnson, C., Lu, Q., Partridge, J. R., Patskovska, L., Patskovsky, Y., et al. (2017) · ACS Medicinal Chemistry Letters

Hemoglobinopathies and Related DisordersHemoglobin structure and function

Cited by 203

Panoramic view of a superfamily of phosphatases through substrate profiling

Huang, H., Pandya, C., Liu, C., Al-Obaidi, N. F., Wang, M., Zheng, L., Toews Keating, S., Aono, M., Love, J. D., Evans, B., et al. (2015) · Proceedings of the National Academy of Sciences

Enzyme Structure and FunctionGenomics and Phylogenetic Studies

Cited by 168

Structural Effects of Cofilin on Longitudinal Contacts in F-actin

Bobkov, A. A., Muhlrad, A., Kokabi, K., Vorobiev, S., Almo, S. C., & Reisler, E. (2002) · Journal of Molecular Biology

Cellular Mechanics and InteractionsProtein Structure and Dynamics

Cited by 70