Hyman, Anthony A.

Liquid-Liquid Phase Separation in Biology

Hyman, A. A., Weber, C. A., & Jülicher, F. (2014) · Annual Review of Cell and Developmental Biology

RNA Research and SplicingProtein Structure and Dynamics

Cited by 3,155

A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

Hein, M. Y., Hubner, N. C., Poser, I., Cox, J., Nagaraj, N., Toyoda, Y., Gak, I. A., Weisswange, I., Mansfeld, J., Buchholz, F., et al. (2015) · Cell

Bioinformatics and Genomic NetworksAdvanced Proteomics Techniques and Applications

Cited by 1,270

Tau protein liquid–liquid phase separation can initiate tau aggregation

Wegmann, S., Eftekharzadeh, B., Tepper, K., Zoltowska, K. M., Bennett, R. E., Dujardin, S., Laskowski, P. R., MacKenzie, D., Kamath, T., Commins, C., et al. (2018) · The EMBO Journal

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 1,102

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers

Vermeulen, M., Eberl, H. C., Matarese, F., Marks, H., Denissov, S., Butter, F., Lee, K. K., Olsen, J. V., Hyman, A. A., Stunnenberg, H. G., et al. (2010) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 806

Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner

Varga, V., Helenius, J., Tanaka, K., Hyman, A. A., Tanaka, T. U., & Howard, J. (2006) · Nature Cell Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 445

Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions

Hubner, N. C., Bird, A. W., Cox, J., Splettstoesser, B., Bandilla, P., Poser, I., Hyman, A., & Mann, M. (2010) · Journal of Cell Biology

Advanced Proteomics Techniques and ApplicationsBiotin and Related Studies

Cited by 440

Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase

Hernández-Vega, A., Braun, M., Scharrel, L., Jahnel, M., Wegmann, S., Hyman, B. T., Alberti, S., Diez, S., & Hyman, A. A. (2017) · Cell Reports

Microtubule and mitosis dynamicsAlzheimer's disease research and treatments

Cited by 395

A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility

Bassik, M. C., Kampmann, M., Lebbink, R. J., Wang, S., Hein, M. Y., Poser, I., Weibezahn, J., Horlbeck, M. A., Chen, S., Mann, M., et al. (2013) · Cell

Toxin Mechanisms and ImmunotoxinsRNA Interference and Gene Delivery

Cited by 365

Microtubule polymerases and depolymerases

Howard, J., & Hyman, A. A. (2007) · Current Opinion in Cell Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 294

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation

Naumann, M., Pal, A., Goswami, A., Lojewski, X., Japtok, J., Vehlow, A., Naujock, M., Günther, R., Jin, M., Stanslowsky, N., et al. (2018) · Nature Communications

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 275

Stoichiometry of chromatin-associated protein complexes revealed by label-free quantitative mass spectrometry-based proteomics

Smits, A. H., Jansen, P. W. T. C., Poser, I., Hyman, A. A., & Vermeulen, M. (2013) · Nucleic Acids Research

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 258

Structural changes accompanying GTP hydrolysis in microtubules: information from a slowly hydrolyzable analogue guanylyl-(alpha,beta)-methylene-diphosphonate.

Hyman, A. A., Chrétien, D., Arnal, I., & Wade, R. H. (1995) · The Journal of cell biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 240

Suppression of Ostwald ripening in active emulsions

Zwicker, D., Hyman, A. A., & Jülicher, F. (2015) · Physical Review E

Pickering emulsions and particle stabilizationMicro and Nano Robotics

Cited by 234

Site-specific cryo-focused ion beam sample preparation guided by 3D correlative microscopy

Arnold, J., Mahamid, J., Lucic, V., de Marco, A., Fernandez, J.-J., Laugks, T., Mayer, T., Hyman, A. A., Baumeister, W., & Plitzko, J. M. (2016) · Biophysical Journal

Advanced Electron Microscopy Techniques and ApplicationsAdvanced Materials Characterization Techniques

Cited by 221

Kinetically distinct phases of tau on microtubules regulate kinesin motors and severing enzymes

Siahaan, V., Krattenmacher, J., Hyman, A. A., Diez, S., Hernández-Vega, A., Lansky, Z., & Braun, M. (2019) · Nature Cell Biology

Alzheimer's disease research and treatmentsMicrotubule and mitosis dynamics

Cited by 169

Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy

Marrone, L., Poser, I., Casci, I., Japtok, J., Reinhardt, P., Janosch, A., Andree, C., Lee, H. O., Moebius, C., Koerner, E., et al. (2018) · Stem Cell Reports

Amyotrophic Lateral Sclerosis ResearchPluripotent Stem Cells Research

Cited by 104

A genomic toolkit to investigate kinesin and myosin motor function in cells

Maliga, Z., Junqueira, M., Toyoda, Y., Ettinger, A., Mora-Bermúdez, F., Klemm, R. W., Vasilj, A., Guhr, E., Ibarlucea-Benitez, I., Poser, I., et al. (2013) · Nature Cell Biology

Microtubule and mitosis dynamicsBiotin and Related Studies

Cited by 103

Microtubule-associated protein-dependent binding of phagosomes to microtubules

Blocker, A., Severin, F. F., Habermann, A., Hyman, A. A., Griffiths, G., & Burkhardt, J. K. (1996) · Journal of Biological Chemistry

Microtubule and mitosis dynamicsCellular transport and secretion

Cited by 81

Stem cells: the new “model organism”

Drubin, D. G., & Hyman, A. A. (2017) · Molecular Biology of the Cell

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 34