Microtubule polymerases and depolymerases

Mechanics of Motor Proteins and the Cytoskeleton

Howard, & Clark (2002) · Applied Mechanics Reviews · doi:10.1115/1.1451234 · Cited by 2,909 · see citing works

Dynamics and mechanics of the microtubule plus end

Howard, J., & Hyman, A. A. (2003) · Nature · doi:10.1038/nature01600 · Cited by 750 · see citing works

Kin I kinesins are microtubule-destabilizing enzymes

Desai, A., Verma, S., Mitchison, T. J., & Walczak, C. E. (1999) · Cell · doi:10.1016/s0092-8674(00)80960-5 · Cited by 708 · see citing works

Assembly dynamics of microtubules at molecular resolution

Kerssemakers, J., Munteanu, E., Laan, L., Noetzel, T., Janson, M., & Dogterom, M. (2006) · Nature · doi:10.1038/nature04928 · Cited by 586 · see citing works

The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends

Helenius, J., Brouhard, G., Kalaidzidis, Y., Diez, S., & Howard, J. (2006) · Nature · doi:10.1038/nature04736 · Cited by 454 · see citing works

Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner

Varga, V., Helenius, J., Tanaka, K., Hyman, A. A., Tanaka, T. U., & Howard, J. (2006) · Nature Cell Biology · doi:10.1038/ncb1462 · Cited by 445 · see citing works

CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex

Mimori‐Kiyosue, Y., Grigoriev, I., Lansbergen, G. W. A., Sasaki, H., Matsui, C., Severin, F. F., Galjart, N., Grosveld, F. G., Vorobjev, I. A., Tsukita, S., et al. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200405094 · Cited by 413 · see citing works

The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends.

Hunter, A., Caplow, M., Coy, D. L., Hancock, W., Diez, S., Wordeman, L., & Howard, J. (2003) · Molecules and Cells · doi:10.1016/s1097-2765(03)00049-2 · Cited by 404 · see citing works

A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end.

Gard, D. L., & Kirschner, M. W. (1987) · The Journal of Cell Biology · doi:10.1083/jcb.105.5.2203 · Cited by 340 · see citing works

Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle

Gupta, M. L., Carvalho, P., Roof, D. M., & Pellman, D. S. (2006) · Nature Cell Biology · doi:10.1038/ncb1457 · Cited by 322 · see citing works

Microtubule plus-end-tracking proteins: mechanisms and functions

Akhmanova, A. S., & Hoogenraad, C. C. (2004) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2004.11.001 · Cited by 319 · see citing works

Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly

Wang, H., & Nogales, E. (2005) · Nature · doi:10.1038/nature03606 · Cited by 316 · see citing works

Formation of a Dynamic Kinetochore- Microtubule Interface through Assembly of the Dam1 Ring Complex

Westermann, S., Avila-Sakar, A., Wang, H., et al. (2005) · Molecular Cell · doi:10.1016/j.molcel.2004.12.019 · Cited by 298 · see citing works

The yeast DASH complex forms closed rings on microtubules

Miranda, J. L., Wulf, P. D., Sorger, P. K., & Harrison, S. C. (2005) · Nature Structural & Molecular Biology · doi:10.1038/nsmb896 · Cited by 277 · see citing works

Length Control of the Metaphase Spindle

Goshima, G., Wollman, R., Stuurman, N., Scholey, J. M., & Vale, R. D. (2005) · Current Biology · doi:10.1016/j.cub.2005.09.054 · Cited by 266 · see citing works

The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends

Westermann, S., Wang, H., Avila-Sakar, A., Drubin, D. G., Nogales, E., & Barnes, G. (2006) · Nature · doi:10.1038/nature04409 · Cited by 263 · see citing works

Force generation by dynamic microtubules

Dogterom, M., Kerssemakers, J. W. J., Romet‐Lemonne, G., & Janson, M. E. (2004) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2004.12.011 · Cited by 258 · see citing works

Flagellar Length Control System: Testing a Simple Model Based on Intraflagellar Transport and Turnover

Marshall, W. F., Qin, H., Rodrigo-Brenni, M. C., & Rosenbaum, J. L. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-07-0586 · Cited by 241 · see citing works

Microtubule Plus End: A Hub of Cellular Activities

Lansbergen, G. W. A., & Akhmanova, A. S. (2006) · Traffic · doi:10.1111/j.1600-0854.2006.00400.x · Cited by 235 · see citing works

Identification and Characterization of Factors Required for Microtubule Growth and Nucleation in the Early C. elegans Embryo

Srayko, M., Kaya-Çopur, A., Stamford, J., & Hyman, A. A. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.07.003 · Cited by 233 · see citing works

Architecture of the budding yeast kinetochore reveals a conserved molecular core

Westermann, S., Cheeseman, I. M., Anderson, S., Yates, J. R., Drubin, D. G., & Barnes, G. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200305100 · Cited by 215 · see citing works

Reconstitution of Physiological Microtubule Dynamics Using Purified Components

Kinoshita, K., Arnal, I., Desai, A. B., Drechsel, D. N., & Hyman, A. A. (2001) · Science · doi:10.1126/science.1064629 · Cited by 212 · see citing works

EB1 and EB3 Control CLIP Dissociation from the Ends of Growing Microtubules

Komarova, Y. A., Lansbergen, G. W. A., Galjart, N., Grosveld, F. G., Borisy, G. G., & Akhmanova, A. S. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-07-0614 · Cited by 200 · see citing works

Structural intermediates in microtubule assembly and disassembly: how and why?

Nogales, E., & Wang, H. (2006) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2006.02.009 · Cited by 189 · see citing works

The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement

Asbury, C. L., Gestaut, D. R., Powers, A. F., Franck, A. D., & Davis, T. N. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602249103 · Cited by 186 · see citing works

Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase

Mennella, V., Rogers, G. C., Rogers, S. L., Buster, D. W., Vale, R. D., & Sharp, D. J. (2005) · Nature Cell Biology · doi:10.1038/ncb1222 · Cited by 154 · see citing works

A Kinesin-like Motor Inhibits Microtubule Dynamic Instability

Bringmann, H., Skiniotis, G., Spilker, A. C., Kandels-Lewis, S. E., Vernos, I., & Surrey, T. (2004) · Science · doi:10.1126/science.1094838 · Cited by 152 · see citing works

Mitotic motors in Saccharomyces cerevisiae

Hildebrandt, E. R., & Hoyt, M. A. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(00)00012-4 · Cited by 148 · see citing works

Distinct roles of doublecortin modulating the microtubule cytoskeleton

Moores, C. A., Perderiset, M., Kappeler, C., Kain, S., Drummond, D. R., Perkins, S. J., Chelly, J., Cross, R. A., Houdusse, A., & Francis, F. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601335 · Cited by 148 · see citing works

MCAK associates with the tips of polymerizing microtubules

Moore, A. T., Rankin, K. E., von Dassow, G., Peris, L., Wagenbach, M., Ovechkina, Y., Andrieux, A., Job, D., & Wordeman, L. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200411089 · Cited by 141 · see citing works

Cik1 Targets the Minus-End Kinesin Depolymerase Kar3 to Microtubule Plus Ends

Sproul, L. R., Anderson, D. J., Mackey, A. T., Saunders, W. S., & Gilbert, S. P. (2005) · Current Biology · doi:10.1016/j.cub.2005.06.066 · Cited by 130 · see citing works

Stu2p binds tubulin and undergoes an open-to-closed conformational change

Al‐Bassam, J., van Breugel, M., Harrison, S. C., et al. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200511010 · Cited by 128 · see citing works

Microtubule dynamics

Heald, R., & Nogales, E. (2002) · Journal of Cell Science · doi:10.1242/jcs.115.1.3 · Cited by 128 · see citing works

The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast

Sánchez‐Pérez, I., Renwick, S. J., Crawley, K., Karig, I., Buck, V., Meadows, J. C., Franco, A., Fleig, U. N., Toda, T., & Millar, J. B. A. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600761 · Cited by 124 · see citing works

Stu2p, the budding yeast member of the conserved Dis1/XMAP215 family of microtubule-associated proteins is a plus end–binding microtubule destabilizer

van Breugel, M., Drechsel, D. N., & Hyman, A. A. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200211097 · Cited by 121 · see citing works

The Nucleotide Switch of Tubulin and Microtubule Assembly: A Polymerization-Driven Structural Change

Buey, R. M., Díaz, J. F., & Andreu, J. M. (2006) · Biochemistry · doi:10.1021/bi060334m · Cited by 118 · see citing works

How motor proteins influence microtubule polymerization dynamics

Hunter, A. W., & Wordeman, L. G. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.24.4379 · Cited by 116 · see citing works

Analysis of kinesin motor function at budding yeast kinetochores

Tytell, J. D., & Sorger, P. K. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200509101 · Cited by 116 · see citing works

Identification of XMAP215 as a microtubule-destabilizing factor in Xenopus egg extract by biochemical purification

Shirasu‐Hiza, M., Coughlin, P., & Mitchison, T. J. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200211095 · Cited by 100 · see citing works

XMAP215 is a long thin molecule that does not increase microtubule stiffness

Cassimeris, L., Gard, D. L., Tran, P. T., et al. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.16.3025 · Cited by 99 · see citing works

Lucky 13-microtubule depolymerisation by kinesin-13 motors

Moores, C. A., & Milligan, R. A. (2006) · Journal of Cell Science · doi:10.1242/jcs.03224 · Cited by 92 · see citing works

Mini spindles, the XMAP215 homologue, suppresses pausing of interphase microtubules in Drosophila

Brittle, A. L., & Ohkura, H. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600629 · Cited by 85 · see citing works

S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent mannerPreprint

Grallert, Á., Beuter, C., Craven, R. A., et al. (2006) · Genes & Development · doi:10.1101/gad.381306 · Cited by 58 · see citing works

Kinesin-13s form rings around microtubules

Tan, D., Asenjo, A. B., Mennella, V., Sharp, D. J., & Sosa, H. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200605194 · Cited by 55 · see citing works

Drosophila Nod Protein Binds Preferentially to the Plus Ends of Microtubules and Promotes Microtubule Polymerization In Vitro

Cui, W., Sproul, L. R., Gustafson, S. M., et al. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-06-0582 · Cited by 47 · see citing works

Microtubule binding proteins CLIP‐170, EB1, and p150Glued form distinct plus‐end complexes

Ligon, L. A., Shelly, S. S., Tokito, M. K., et al. (2006) · FEBS Letters · doi:10.1016/j.febslet.2006.01.050 · Cited by 45 · see citing works

The Role of the Kinesin-13 Neck in Microtubule Depolymerization

Moores, C. A., Cooper, J. R., Wagenbach, M., et al. (2006) · Cell Cycle · doi:10.4161/cc.5.16.3134 · Cited by 42 · see citing works

Kar3 interaction with Cik1 alters motor structure and function

Chu, H. M. A., Yun, M., Anderson, D. E., Sage, H. J., Park, H., & Endow, S. A. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600790 · Cited by 37 · see citing works

Global and local control of microtubule destabilization promoted by a catastrophe kinesin MCAK/XKCM1

Kinoshita, K., Noetzel, T. L., Arnal, I., Drechsel, D. N., & Hyman, A. A. (2006) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-005-9045-2 · Cited by 24 · see citing works

A comparison of the ability of XMAP215 and tau to inhibit the microtubule destabilizing activity of XKCM1

Noetzel, T. L., Drechsel, D. N., Hyman, A. A., & Kinoshita, K. (2005) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2004.1613 · Cited by 22 · see citing works

A minimal midzone protein module controls formation and length of antiparallel microtubule overlaps

Bieling, P., Telley, I. A., & Surrey, T. (2010) · Cell · doi:10.1016/j.cell.2010.06.033 · Cited by 326 · see citing works

A complex of Kif18b and MCAK promotes microtubule depolymerization and is negatively regulated by Aurora kinases

Tanenbaum, M. E., Macurek, L., van der Vaart, B., Galli, M., Akhmanova, A., & Medema, R. H. (2011) · Current Biology · doi:10.1016/j.cub.2011.07.017 · Cited by 148 · see citing works

In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends

Montenegro Gouveia, S., Leslie, K., Kapitein, L. C., Buey, R. M., Grigoriev, I., Wagenbach, M., Smal, I., Meijering, E., Hoogenraad, C. C., Wordeman, L., et al. (2010) · Current Biology · doi:10.1016/j.cub.2010.08.020 · Cited by 147 · see citing works

Aurora A phosphorylates MCAK to control ran-dependent spindle bipolarity

Zhang, X., Ems-McClung, S. C., & Walczak, C. E. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-02-0198 · Cited by 123 · see citing works

Kif18B interacts with EB1 and controls astral microtubule length during mitosis

Stout, J. R., Yount, A. L., Powers, J. A., LeBlanc, C., Ems-McClung, S. C., & Walczak, C. E. (2011) · Molecular Biology of the Cell · doi:10.1091/mbc.e11-04-0363 · Cited by 111 · see citing works

MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport

Tymanskyj, S. R., Yang, B. H., Verhey, K. J., & Ma, L. (2018) · eLife · doi:10.7554/elife.36374 · Cited by 77 · see citing works

Single-molecule investigation of the interference between kinesin, tau and MAP2c

Seitz, A., Kojima, H., Oiwa, K., Mandelkow, E.-M., Song, Y.-H., & Mandelkow, E. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf503 · Cited by 257 · see citing works

The Balance Between τ Protein's Microtubule Growth and Nucleation Activities: Implications for the Formation of Axonal Microtubules

Brandt, R., & Lee, G. S. (1993) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1993.tb03613.x · Cited by 60 · see citing works

Microtubule Acetylation Promotes Kinesin-1 Binding and Transport

Reed, N. A., Cai, D., Blasius, T. L., Jih, G. T., Meyhofer, E., Gaertig, J., & Verhey, K. J. (2006) · Current Biology · doi:10.1016/j.cub.2006.09.014 · Cited by 919 · see citing works

Elucidating the mechanism of cortical microtubule reorientation in plant cells

Wymer, C. L., Fisher, D. D., Moore, R. C., & Cyr, R. J. (1996) · Cell Motility and the Cytoskeleton · doi:10.1002/(sici)1097-0169(1996)35:2 · Cited by 40 · see citing works