Zhao, Zhongming

The repertoire of mutational signatures in human cancer

Alexandrov, L. B., Kim, J., Haradhvala, N. J., Huang, M. N., Tian Ng, A. W., Wu, Y., Boot, A., Covington, K. R., Gordenin, D. A., Bergstrom, E. N., et al. (2020) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 3,496

Pan-cancer analysis of whole genomes

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Aaltonen, L. A., Abascal, F., Abeshouse, A., Aburatani, H., Adams, D. J., Agrawal, N., Ahn, K. S., Ahn, S.-M., Aikata, H., et al. (2020) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 3,064

Asprosin is a centrally acting orexigenic hormone

Duerrschmid, C., He, Y., Wang, C., Li, C., Bournat, J. C., Romere, C., Saha, P. K., Lee, M. E., Phillips, K. J., Jain, M., et al. (2017) · Nature Medicine

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 357

Hdac3 is essential for the maintenance of chromatin structure and genome stability

Bhaskara, S., Knutson, S. K., Jiang, G., Chandrasekharan, M. B., Wilson, A. J., Zheng, S., Yenamandra, A., Locke, K., Yuan, J.-L., Bonine-Summers, A. R., et al. (2010) · Cancer Cell

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 353

Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC

Thomas, L. R., Wang, Q., Grieb, B. C., Phan, J., Foshage, A. M., Sun, Q., Olejniczak, E. T., Clark, T., Dey, S., Lorey, S., et al. (2015) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 310

Moderate mutation rate in the SARS coronavirus genome and its implications

Zhao, Z., Li, H., Wu, X., Zhong, Y., Zhang, K., Zhang, Y.-P., Boerwinkle, E., & Fu, Y.-X. (2004) · BMC Evolutionary Biology

SARS-CoV-2 and COVID-19 ResearchEvolution and Genetic Dynamics

Cited by 286

Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

Akdemir, K. C., Le, V. T., Chandran, S., Li, Y., Verhaak, R. G., Beroukhim, R., Campbell, P. J., Chin, L., Dixon, J. R., Futreal, P. A., et al. (2020) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 283

Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer

Lovly, C. M., McDonald, N. T., Chen, H., Ortiz-Cuaran, S., Heukamp, L. C., Yan, Y., Florin, A., Ozretić, L., Lim, D., Wang, L., et al. (2014) · Nature Medicine

Lung Cancer Treatments and MutationsLung Cancer Research Studies

Cited by 268

Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides

McGirt, L. Y., Jia, P., Baerenwald, D. A., Duszynski, R. J., Dahlman, K. B., Zic, J. A., Zwerner, J. P., Hucks, D., Dave, U., Zhao, Z., et al. (2015) · Blood

Cutaneous lymphoproliferative disorders researchLymphoma Diagnosis and Treatment

Cited by 232

Gene set analysis of genome-wide association studies: Methodological issues and perspectives

Wang, L., Jia, P., Wolfinger, R. D., Chen, X., & Zhao, Z. (2011) · Genomics

Bioinformatics and Genomic NetworksGenetic Associations and Epidemiology

Cited by 207

Gene2Vec: Distributed Representation of Genes Based on Co-Expression

Du, J., Jia, P., Dai, Y., Tao, C., Zhao, Z., & Zhi, D. (2018) · BMC Genomics

Bioinformatics and Genomic NetworksGene expression and cancer classification

Cited by 204

A Meta-analysis of Somatic Mutations from Next Generation Sequencing of 241 Melanomas: A Road Map for the Study of Genes with Potential Clinical Relevance

Xia, J., Jia, P., Hutchinson, K. E., Dahlman, K. B., Johnson, D., Sosman, J., Pao, W., & Zhao, Z. (2014) · Molecular Cancer Therapeutics

Melanoma and MAPK PathwaysCancer Genomics and Diagnostics

Cited by 94

Age-associated telomere attrition in adipocyte progenitors predisposes to metabolic disease

Gao, Z., Daquinag, A. C., Fussell, C., Zhao, Z., Dai, Y., Rivera, A., Snyder, B. E., Eckel-Mahan, K. L., & Kolonin, M. G. (2020) · Nature Metabolism

Adipose Tissue and MetabolismTelomeres, Telomerase, and Senescence

Cited by 92

Acquired Resistance of EGFR-Mutant Lung Adenocarcinomas to Afatinib plus Cetuximab Is Associated with Activation of mTORC1

Pirazzoli, V., Nebhan, C., Song, X., Wurtz, A., Walther, Z., Cai, G., Zhao, Z., Jia, P., de Stanchina, E., Shapiro, E. M., et al. (2014) · Cell Reports

Lung Cancer Treatments and MutationsPI3K/AKT/mTOR signaling in cancer

Cited by 71

Enzalutamide-induced signatures revealed by epigenetic plasticity using single-cell multi-omics sequencing in prostate cancer

Fan, H., Li, J., Manuel, A. M., & Zhao, Z. (2023) · Molecular Therapy - Nucleic Acids

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

Cited by 14