McSorley, Henry J.

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

Buck, A. H., Coakley, G., Simbari, F., McSorley, H. J., Quintana, J. F., Le Bihan, T., Kumar, S., Abreu-Goodger, C., Lear, M., Harcus, Y., et al. (2014) · Nature Communications

Parasites and Host InteractionsExtracellular vesicles in disease

Cited by 770

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

Grainger, J. R., Smith, K. A., Hewitson, J. P., McSorley, H. J., Harcus, Y., Filbey, K. J., Finney, C. A. M., Greenwood, E. J. D., Knox, D. P., Wilson, M. S., et al. (2010) · Journal of Experimental Medicine

Parasites and Host InteractionsT-cell and B-cell Immunology

Cited by 469

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

Maizels, R. M., Smits, H. H., & McSorley, H. J. (2018) · Immunity

Parasites and Host InteractionsHelminth infection and control

Cited by 435

Extracellular vesicles from a helminth parasite suppress macrophage activation and constitute an effective vaccine for protective immunity

Coakley, G., McCaskill, J. L., Borger, J. G., Simbari, F., Robertson, E., Millar, M., Harcus, Y., McSorley, H. J., Maizels, R. M., & Buck, A. H. (2017) · Cell Reports

Parasites and Host InteractionsHelminth infection and control

Cited by 219

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

Johnston, C. J. C., Smyth, D. J., Kodali, R. B., White, M. P. J., Harcus, Y., Filbey, K. J., Hewitson, J. P., Hinck, C. S., Ivens, A., Kemter, A. M., et al. (2017) · Nature Communications

Parasites and Host InteractionsT-cell and B-cell Immunology

Cited by 197

HpARI protein secreted by a helminth parasite suppresses interleukin-33

Osbourn, M., Soares, D. C., Vacca, F., Cohen, E. S., Scott, I. C., Gregory, W. F., Smyth, D. J., Toivakka, M., Kemter, A. M., le Bihan, T., et al. (2017) · Immunity

IL-33, ST2, and ILC PathwaysParasites and Host Interactions

Cited by 178

Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy

McSorley, H. J., Blair, N. F., Smith, K. A., McKenzie, A. N. J., & Maizels, R. M. (2014) · Mucosal Immunology

IL-33, ST2, and ILC PathwaysAsthma and respiratory diseases

Cited by 163

Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity

Hewitson, J. P., Ivens, A. C., Harcus, Y., Filbey, K. J., McSorley, H. J., Murray, J., Bridgett, S., Ashford, D., Dowle, A. A., & Maizels, R. M. (2013) · PLoS Pathogens

Parasites and Host InteractionsHelminth infection and control

Cited by 71

Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis

Robb, C. T., McSorley, H. J., Lee, J., Aoki, T., Yu, C., Crittenden, S., Astier, A., Felton, J. M., Parkinson, N., Ayele, A., et al. (2018) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 68

TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus

Smyth, D. J., Harcus, Y., White, M. P. J., Gregory, W. F., Nahler, J., Stephens, I., Toke-Bjolgerud, E., Hewitson, J. P., Ivens, A., McSorley, H. J., et al. (2018) · International Journal for Parasitology

Parasites and Host InteractionsHelminth infection and control

Cited by 66