Linker, Sara B.

The role of adult hippocampal neurogenesis in brain health and disease

Toda, T., Parylak, S. L., Linker, S. B., & Gage, F. H. (2019) · Molecular Psychiatry

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 719

The role of retrotransposable elements in ageing and age-associated diseases

Gorbunova, V., Seluanov, A., Mita, P., McKerrow, W., Fenyö, D., Boeke, J. D., Linker, S. B., Gage, F. H., Kreiling, J. A., Petrashen, A. P., et al. (2021) · Nature

Chromosomal and Genetic VariationsGenetics, Aging, and Longevity in Model Organisms

Cited by 446

Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons

Krishnaswami, S. R., Grindberg, R. V., Novotny, M., Venepally, P., Lacar, B., Bhutani, K., Linker, S. B., Pham, S., Erwin, J. A., Miller, J. A., et al. (2016) · Nature Protocols

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 445

Nuclear RNA-seq of single neurons reveals molecular signatures of activation

Lacar, B., Linker, S. B., Jaeger, B. N., Krishnaswami, S. R., Barron, J. J., Kelder, M. J. E., Parylak, S. L., Paquola, A. C. M., Venepally, P., Novotny, M., et al. (2016) · Nature Communications

Single-cell and spatial transcriptomicsMemory and Neural Mechanisms

Cited by 405

Species-specific maturation profiles of human, chimpanzee and bonobo neural cells

Marchetto, M. C., Hrvoj-Mihic, B., Kerman, B. E., Yu, D. X., Vadodaria, K. C., Linker, S. B., Narvaiza, I., Santos, R., Denli, A. M., Mendes, A. P., et al. (2019) · eLife

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 132

Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons

Reid, D. A., Reed, P. J., Schlachetzki, J. C. M., Nitulescu, I. I., Chou, G., Tsui, E. C., Jones, J. R., Chandran, S., Lu, A. T., McClain, C. A., et al. (2021) · Science

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 121

IGF-1 treatment causes unique transcriptional response in neurons from individuals with idiopathic autism

Linker, S. B., Mendes, A. P. D., & Marchetto, M. C. (2020) · Molecular Autism

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 31

BrainImageR: spatiotemporal gene set analysis referencing the human brain

Linker, S. B., Hsu, J. Y., Pfaff, A., Amatya, D., Ko, S.-M., Voter, S., Wong, Q., & Gage, F. H. (2019) · Bioinformatics

Bioinformatics and Genomic NetworksSingle-cell and spatial transcriptomics

Cited by 7