Oldham, Michael C.

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

Sorrells, S. F., Paredes, M. F., Cebrian-Silla, A., Sandoval, K., Qi, D., Kelley, K. W., James, D., Mayer, S., Chang, J., Auguste, K. I., et al. (2018) · Nature

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 1,422

Is My Network Module Preserved and Reproducible?

Langfelder, P., Luo, R., Oldham, M. C., & Horvath, S. (2011) · PLoS Computational Biology

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 1,012

Molecular Identity of Human Outer Radial Glia during Cortical Development

Pollen, A. A., Nowakowski, T. J., Chen, J., Retallack, H., Sandoval-Espinosa, C., Nicholas, C. R., Shuga, J., Liu, S. J., Oldham, M. C., Diaz, A., et al. (2015) · Cell

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 908

Functional organization of the transcriptome in human brain

Oldham, M. C., Konopka, G., Iwamoto, K., Langfelder, P., Kato, T., Horvath, S., & Geschwind, D. H. (2008) · Nature Neuroscience

Gene expression and cancer classificationSingle-cell and spatial transcriptomics

Cited by 752

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

Lui, H., Zhang, J., Makinson, S. R., Cahill, M. K., Kelley, K. W., Huang, H.-Y., Shang, Y., Oldham, M. C., Martens, L. H., Gao, F., et al. (2016) · Cell

Neuroinflammation and Neurodegeneration MechanismsAmyotrophic Lateral Sclerosis Research

Cited by 729

Conservation and evolution of gene coexpression networks in human and chimpanzee brains

Oldham, M. C., Horvath, S., & Geschwind, D. H. (2006) · Proceedings of the National Academy of Sciences

Bioinformatics and Genomic NetworksGenomics and Phylogenetic Studies

Cited by 566

A Systems Level Analysis of Transcriptional Changes in Alzheimer's Disease and Normal Aging

Miller, J. A., Oldham, M. C., & Geschwind, D. H. (2008) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 385

Human brain evolution: insights from microarrays

Preuss, T. M., Cáceres, M., Oldham, M. C., & Geschwind, D. H. (2004) · Nature Reviews Genetics

Primate Behavior and EcologyGenomic variations and chromosomal abnormalities

Cited by 215

Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes

Kelley, K. W., Nakao-Inoue, H., Molofsky, A. V., & Oldham, M. C. (2018) · Nature Neuroscience

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 198

Neurons show distinctive DNA methylation profile and higher interindividual variations compared with non-neurons

Iwamoto, K., Bundo, M., Ueda, J., Oldham, M. C., Ukai, W., Hashimoto, E., Saito, T., Geschwind, D. H., & Kato, T. (2011) · Genome Research

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 189

Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex

Lui, J. H., Nowakowski, T. J., Pollen, A. A., Javaherian, A., Kriegstein, A. R., & Oldham, M. C. (2014) · Nature

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 166

Network methods for describing sample relationships in genomic datasets: Application to Huntington’s disease

Oldham, M. C., Langfelder, P., & Horvath, S. (2012) · BMC Systems Biology

Gene expression and cancer classificationBioinformatics and Genomic Networks

Cited by 154

Functional Genomic Analyses Identify Pathways Dysregulated by Progranulin Deficiency, Implicating Wnt Signaling

Rosen, E. Y., Wexler, E. M., Versano, R., Coppola, G., Gao, F., Winden, K. D., Oldham, M. C., Martens, L. H., Zhou, P., Farese, R. V., et al. (2011) · Neuron

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 128

The organization of the transcriptional network in specific neuronal classes

Winden, K. D., Oldham, M. C., Mirnics, K., Ebert, P. J., Swan, C. H., Levitt, P., Rubenstein, J. L., Horvath, S., & Geschwind, D. H. (2009) · Molecular Systems Biology

Bioinformatics and Genomic NetworksDevelopmental Biology and Gene Regulation

Cited by 112