Cardiac contractile dysfunction in Lep/Lep obesity is accompanied by NADPH oxidase activation, oxidative modification of sarco(endo)plasmic reticulum Ca2+-ATPase and myosin heavy chain isozyme switch

Positional cloning of the mouse obese gene and its human homologue

Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419 · see citing works

Increased oxidative stress in obesity and its impact on metabolic syndrome

Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21625 · Cited by 5,508 · see citing works

Congenital leptin deficiency is associated with severe early-onset obesity in humans

Montague, C. T., Farooqi, I. S., Whitehead, J. P., Soos, M. A., Rau, H., Wareham, N. J., Sewter, C. P., Digby, J. E., Mohammed, S. N., Hurst, J. A., et al. (1997) · Nature · doi:10.1038/43185 · Cited by 2,936 · see citing works

Diabetes, Obesity, and the Brain

Schwartz, M. W., & Porte, D. (2005) · Science · doi:10.1126/science.1104344 · Cited by 841 · see citing works

The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases

Cai, H., Griendling, K. K., & Harrison, D. G. (2003) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(03)00233-5 · Cited by 687 · see citing works

S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide

Adachi, T. K., Weisbrod, R. M., Pimentel, D. R., Ying, J., Sharov, V. S., Schöneich, C., & Cohen, R. A. (2004) · Nature Medicine · doi:10.1038/nm1119 · Cited by 662 · see citing works

Characteristics of the Inhibition of NADPH Oxidase Activation in Neutrophils by Apocynin, a Methoxy-Substituted Catechol

Stolk, J. N., Hiltermann, T. J. N., Dijkman, J. H., & Verhoeven, A. J. (1994) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/ajrcmb.11.1.8018341 · Cited by 650 · see citing works

Expression of a Functionally Active gp91phox-Containing Neutrophil-Type NAD(P)H Oxidase in Smooth Muscle Cells From Human Resistance Arteries: Regulation by Angiotensin II

Touyz, R. M., Chen, X., Tabet, F., Yao, G., He, G., Quinn, M. T., Pagano, P. J., & Schiffrin, E. L. (2002) · Circulation Research · doi:10.1161/01.res.0000020404.01971.2f · Cited by 590 · see citing works

Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase

McClung, J. P., Roneker, C. A., Mu, W., Lisk, D. J., Langlais, P., Liu, F., & Lei, X. G. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308096101 · Cited by 536 · see citing works

Oxidative stress and protein aggregation during biological aging

Squier, T. C. (2001) · Experimental Gerontology · doi:10.1016/s0531-5565(01)00139-5 · Cited by 511 · see citing works

Reduced Mitochondrial Oxidative Capacity and Increased Mitochondrial Uncoupling Impair Myocardial Energetics in Obesity

Boudina, S., Sena, S., O’Neill, B. T., Tathireddy, P., Young, M. E., & Abel, E. D. (2005) · Circulation · doi:10.1161/circulationaha.105.554360 · Cited by 502 · see citing works

Myocardial Gene Expression in Dilated Cardiomyopathy Treated with Beta-Blocking Agents

Lowes, B. D., Gilbert, E. M., Abraham, W. T., Minobe, W. A., Larrabee, P., Ferguson, D. A., Wolfel, E. E., Lindenfeld, J., Tsvetkova, T. O., Robertson, A. D., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012630 · Cited by 500 · see citing works

What Mechanisms Underlie Diastolic Dysfunction in Heart Failure?

Kass, D. A., Bronzwaer, J. G. F., & Paulus, W. J. (2004) · Circulation Research · doi:10.1161/01.res.0000129254.25507.d6 · Cited by 474 · see citing works

Proteins as biomarkers of oxidative/nitrosative stress in diseases: The contribution of redox proteomics

Dalle‐Donne, I., Scaloni, A., Giustarini, D., Cavarra, E., Tell, G., Lungarella, G., Colombo, R., Rossi, R., & Milzani, A. (2004) · Mass Spectrometry Reviews · doi:10.1002/mas.20006 · Cited by 448 · see citing works

Impaired Cardiac Efficiency and Increased Fatty Acid Oxidation in Insulin-Resistant <i>ob/ob</i> Mouse Hearts

Mazumder, P. K., O’Neill, B. T., Roberts, M. W., Buchanan, J., Yun, U. J., Cooksey, R. C., Boudina, S., & Abel, E. D. (2004) · Diabetes · doi:10.2337/diabetes.53.9.2366 · Cited by 437 · see citing works

Intracellular Localization and Preassembly of the NADPH Oxidase Complex in Cultured Endothelial Cells

Li, J., & Shah, A. M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m110073200 · Cited by 395 · see citing works

Leptin and hyperleptinemia - from friend to foe for cardiovascular function

Ren, J. (2004) · Journal of Endocrinology · doi:10.1677/joe.0.1810001 · Cited by 305 · see citing works

Impact of beta-myosin heavy chain expression on cardiac function during stress

Krenz, M., & Robbins, J. M. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.09.044 · Cited by 259 · see citing works

Report of the National Heart, Lung, and Blood Institute-National Institute of Diabetes and Digestive and Kidney Diseases Working Group on the Pathophysiology of Obesity-Associated Cardiovascular Disease

Eckel, R. H., Barouch, W. W., & Ershow, A. G. (2002) · Circulation · doi:10.1161/01.cir.0000017823.53114.4c · Cited by 256 · see citing works

Decreased Sarcoplasmic Reticulum Activity and Contractility in Diabetic db/db Mouse Heart

Belke, D. D., Swanson, E. A., & DILLMANN, W. H. (2004) · Diabetes · doi:10.2337/diabetes.53.12.3201 · Cited by 253 · see citing works

Leptin Induces Hypertrophy via Endothelin-1–Reactive Oxygen Species Pathway in Cultured Neonatal Rat Cardiomyocytes

Xu, F.-P., Chen, M.-S., Wang, Y.-Z., Yi, Q., Lin, S.-B., Chen, A. F., & Luo, J.-D. (2004) · Circulation · doi:10.1161/01.cir.0000140766.52771.6d · Cited by 234 · see citing works

Leptin, obesity, and respiratory function

O'Donnell, C. P., Tankersley, C. G., Polotsky, V. P., Schwartz, A. R., & Smith, P. L. (2000) · Respiration Physiology · doi:10.1016/s0034-5687(99)00111-5 · Cited by 233 · see citing works

AT 1 Blockade Prevents Glucose-Induced Cardiac Dysfunction in Ventricular Myocytes

Privratsky, J. R., Wold, L. E., Sowers, J. R., Quinn, M. T., & Ren, J. T. (2003) · Hypertension · doi:10.1161/01.hyp.0000082814.62655.85 · Cited by 222 · see citing works

Leptin Attenuates Cardiac Contraction in Rat Ventricular Myocytes

Nickola, M. W., Wold, L. E., Colligan, P. B., Wang, G., Samson, W. K., & Ren, J. T. (2000) · Hypertension · doi:10.1161/01.hyp.36.4.501 · Cited by 184 · see citing works

Leptin attenuates respiratory complications associated with the obese phenotype

Tankersley, C. G., O'Donnell, C. P., Daood, M. J., Watchko, J. F., Mitzner, W., Schwartz, A. R., & Smith, P. L. (1998) · Journal of Applied Physiology · doi:10.1152/jappl.1998.85.6.2261 · Cited by 178 · see citing works

Electrophoretic separation and quantitation of cardiac myosin heavy chain isoforms in eight mammalian species

Reiser, P. J., & Kline, W. O. (1998) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1998.274.3.h1048 · Cited by 156 · see citing works

Impaired cardiac contractile function in ventricular myocytes from leptin-deficient ob/ob obese mice

Dong, F., Zhang, X., Yang, X., Esberg, L. B., Yang, H., Zhang, Z., Culver, B., & Ren, J. (2006) · Journal of Endocrinology · doi:10.1677/joe.1.06241 · Cited by 155 · see citing works

Leptin, obesity and cardiovascular disease

Correia, M., & Haynes, W. G. (2004) · Current Opinion in Nephrology & Hypertension · doi:10.1097/00041552-200403000-00010 · Cited by 153 · see citing works

Downregulation of Myocardial Myocyte Enhancer Factor 2C and Myocyte Enhancer Factor 2C–Regulated Gene Expression in Diabetic Patients With Nonischemic Heart Failure

Razeghi, P., Young, M. E., Cockrill, T. C., Frazier, O. H., & Taegtmeyer, H. (2002) · Circulation · doi:10.1161/01.cir.0000026392.80723.dc · Cited by 136 · see citing works

Enhanced Electrophoretic Separation and Resolution of Myosin Heavy Chains in Mammalian and Avian Skeletal Muscles

Blough, E. R., Rennie, E. R., Zhang, F., & Reiser, P. J. (1996) · Analytical Biochemistry · doi:10.1006/abio.1996.0003 · Cited by 125 · see citing works

Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification

Li, S., Du, ‬., Dolence, E. K., Fang, C. X., Mayer, G. E., Ceylan‐Isik, A. F., LaCour, K. H., Yang, X., Wilbert, C. J., Sreejayan, N., et al. (2005) · Aging Cell · doi:10.1111/j.1474-9728.2005.00146.x · Cited by 122 · see citing works

Oxidized proteins as a marker of oxidative stress during coronary heart surgery

Pantke, U., Volk, T. J., Schmutzler, M., Kox, W. J., Sitte, N., & Grune, T. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00144-6 · Cited by 118 · see citing works

Impact of β-myosin heavy chain isoform expression on cross-bridge cycling kinetics

Rundell, V. L. M., Manaves, V., Martin, A. F., & de Tombe, P. P. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00407.2004 · Cited by 117 · see citing works

Changes in Leptin, Plasminogen Activator Factor and Oxidative Stress in Morbidly Obese Patients following Open and Laparoscopic Swedish Adjustable Gastric Banding

Uzun, H., Zengin, K., Taşkın, M., Aydın, S., Şimşek, G., & Darıyerli, N. (2004) · Obesity Surgery · doi:10.1381/096089204323093453 · Cited by 116 · see citing works

Impaired insulin-induced vasodilation in small coronary arteries of Zucker obese rats is mediated by reactive oxygen species

Katakam, P. V. G., Tulbert, C. D., Snipes, J. A., Erdös, B., Miller, A. W., & Busija, D. W. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00715.2004 · Cited by 113 · see citing works

Reduced contractile response to insulin and IGF-I in ventricular myocytes from genetically obese Zucker rats

Ren, J. T., Sowers, J. R., Walsh, M. F., & Brown, R. A. (2000) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2000.279.4.h1708 · Cited by 111 · see citing works

Oxygen Free Radicals and Excitation-Contraction Coupling

Goldhaber, J. I., & Qayyum, M. S. (2000) · Antioxidants and Redox Signaling · doi:10.1089/ars.2000.2.1-55 · Cited by 103 · see citing works

Mouse models of mitochondrial dysfunction and heart failure

Russell, L. K., Finck, B. N., & Kelly, D. J. (2004) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2004.10.010 · Cited by 98 · see citing works

Abrogated Leptin-Induced Cardiac Contractile Response in Ventricular Myocytes Under Spontaneous Hypertension

Wold, L. E., Relling, D. P., Duan, J., Norby, F. L., & Ren, J. T. (2002) · Hypertension · doi:10.1161/hy0102.100777 · Cited by 98 · see citing works

Regulation of intracellular Ca2+ in the heart during diabetes

Pierce, G. N. (1997) · Cardiovascular Research · doi:10.1016/s0008-6363(97)00010-2 · Cited by 91 · see citing works

A newly synthetic chromium complex – chromium(phenylalanine)3 improves insulin responsiveness and reduces whole body glucose tolerance

Yang, X., Palanichamy, K., Ontko, A. C., Rao, M. N. A., Fang, C. X., Ren, J. T., & Sreejayan, N. (2005) · FEBS Letters · doi:10.1016/j.febslet.2005.01.049 · Cited by 87 · see citing works

Combined loss of neuronal and endothelial nitric oxide synthase causes premature mortality and age-related hypertrophic cardiac remodeling in mice

Barouch, L. A. (2003) · Journal of Molecular and Cellular Cardiology · doi:10.1016/s0022-2828(03)00079-8 · Cited by 75 · see citing works

Depressed cardiac tension cost in experimental diabetes is due to altered myosin heavy chain isoform expression

Rundell, V. L. M., Geenen, D. L., Buttrick, P. M., & de Tombe, P. P. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00049.2004 · Cited by 59 · see citing works

Leptin repletion restores depressed β‐adrenergic contractility in <i>ob/ob</i> mice independently of cardiac hypertrophy

Minhas, K. M., Khan, S. A., Raju, S. V. Y., Phan, A. C., Gonzalez, D. R., Skaf, M. W., Lee, K., Tejani, A. D., Saliaris, A. P., Barouch, L. A., et al. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.084566 · Cited by 59 · see citing works

Identification of Oxidized Proteins Based on Sodium Dodecyl Sulfate–Polyacrylamide Gel Electrophoresis, Immunochemical Detection, Isoelectric Focusing, and Microsequencing

Yan, L., Orr, W. C., & Sohal, R. S. (1998) · Analytical Biochemistry · doi:10.1006/abio.1998.2799 · Cited by 58 · see citing works

Age-dependent changes in contraction and regional myocardial myosin heavy chain isoform expression in rats

Carnes, C. A., Geisbuhler, T. P., & Reiser, P. J. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00439.2003 · Cited by 54 · see citing works

Morphological and Functional Alterations in Ventricular Myocytes From Male Transgenic Mice With Hypertrophic Cardiomyopathy

Olsson, M. C., Palmer, B. M., Stauffer, B. L., Leinwand, L. A., & Moore, R. L. (2003) · Circulation Research · doi:10.1161/01.res.0000111521.40760.18 · Cited by 54 · see citing works

Physical conditioning modulates rat cardiac vascular endothelial growth factor gene expression in nitric oxide-deficient hypertension

Husain, K. M. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.06.058 · Cited by 48 · see citing works

Effects of Cardiac Support Device on reverse remodeling: molecular, biochemical, and structural mechanisms

Sabbah, H. N. (2004) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2004.09.009 · Cited by 26 · see citing works

Gender differences in myosin heavy chain-β and phosphorylated phospholamban in diabetic rat hearts

Zhong, Y., Reiser, P. J., & Matlib, M. A. (2003) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00547.2003 · Cited by 20 · see citing works

Lessons from the leptin paradox in cardiac regulation – too much versus too little

Ren, J. T. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.086678 · Cited by 10 · see citing works

Myocardial Fatty Acid Metabolism in Health and Disease

Lopaschuk, G. D., Ussher, J. R., Folmes, C. D. L., Jaswal, J. S., & Stanley, W. C. (2010) · Physiological Reviews · doi:10.1152/physrev.00015.2009 · Cited by 2,180 · see citing works

Diabetic Cardiomyopathy Revisited

Boudina, S., & Abel, E. D. (2007) · Circulation · doi:10.1161/circulationaha.106.679597 · Cited by 1,543 · see citing works

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity

Fu, S., Yang, L., Li, P., Hofmann, O., Dicker, L. H., Hide, W. A., Lin, X., Watkins, S. M., Ivanov, A. R., & Hotamışlıgil, G. S. (2011) · Nature · doi:10.1038/nature09968 · Cited by 1,024 · see citing works

Molecular mechanisms of diabetic cardiomyopathy

Bugger, H., & Abel, E. D. (2014) · Diabetologia · doi:10.1007/s00125-014-3171-6 · Cited by 903 · see citing works

Obesity and hypertension

Seravalle, G., & Grassi, G. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.05.013 · Cited by 909 · see citing works

Cardiac Metabolism and its Interactions With Contraction, Growth, and Survival of Cardiomyocytes

Kolwicz, S. C., Purohit, S., & Tian, R. (2013) · Circulation Research · doi:10.1161/circresaha.113.302095 · Cited by 810 · see citing works

Cardiac remodeling in obesity

Abel, E. D., Litwin, S. E., & Sweeney, G. (2008) · Physiological Reviews · doi:10.1152/physrev.00017.2007 · Cited by 736 · see citing works

Basic Mechanisms of Diabetic Heart Disease

Ritchie, R. H., & Abel, E. D. (2020) · Circulation Research · doi:10.1161/circresaha.120.315913 · Cited by 730 · see citing works

Heart Failure in Type 2 Diabetes Mellitus

Kenny, H., & Abel, E. D. (2019) · Circulation Research · doi:10.1161/circresaha.118.311371 · Cited by 671 · see citing works

Positive and Negative Regulation of Insulin Signaling by Reactive Oxygen and Nitrogen Species

Bashan, N., Kovsan, J., Kachko, I., Ovadia, H., & Rudich, A. (2009) · Physiological Reviews · doi:10.1152/physrev.00014.2008 · Cited by 542 · see citing works

Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications

Ren, J. T., Wu, N. N., Wang, S., Sowers, J. R., & Zhang, Y. (2021) · Physiological Reviews · doi:10.1152/physrev.00030.2020 · Cited by 377 · see citing works

The Physiology of Obese-Hyperglycemic Mice [ob/obMice]

Lindström, P. (2007) · The Scientific World JOURNAL · doi:10.1100/tsw.2007.117 · Cited by 353 · see citing works

Leptin Signaling and Obesity

Yang, R., & Barouch, L. A. (2007) · Circulation Research · doi:10.1161/circresaha.107.156596 · Cited by 331 · see citing works

Redox signaling in cardiac myocytes

Santos, C. X. C., Anilkumar, N. P., Zhang, M., Brewer, A. C., & Shah, A. M. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.01.003 · Cited by 312 · see citing works

Rodent models of diabetic cardiomyopathy

Bugger, H., & Abel, E. D. (2009) · Disease Models & Mechanisms · doi:10.1242/dmm.001941 · Cited by 284 · see citing works

Obesity, metabolic dysfunction, and cardiac fibrosis: pathophysiological pathways, molecular mechanisms, and therapeutic opportunities

Cavalera, M., Wang, J., & Frangogiannis, N. G. (2014) · Translational research · doi:10.1016/j.trsl.2014.05.001 · Cited by 269 · see citing works

Mitochondria in the diabetic heart

Bugger, H., & Abel, E. D. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq239 · Cited by 261 · see citing works

Resveratrol‐enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice

Wang, B., Yang, Q., Sun, Y., Xing, Y., Wang, Y., Lu, X., Bai, W., Liu, X., & Zhao, Y. (2014) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12312 · Cited by 228 · see citing works

Of mice and men: models and mechanisms of diabetic cardiomyopathy

Riehle, C., & Bauersachs, J. K. (2018) · Basic Research in Cardiology · doi:10.1007/s00395-018-0711-0 · Cited by 199 · see citing works

NADPH Oxidases in Heart Failure: Poachers or Gamekeepers?

Zhang, M., Perino, A., Ghigo, A., Hirsch, E., & Shah, A. M. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2012.4550 · Cited by 196 · see citing works

Signaling Pathways Related to Oxidative Stress in Diabetic Cardiomyopathy

Peng, M., Fu, Y., Wu, C.-W., Zhang, Y., Ren, H., & Zhou, S.-S. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.907757 · Cited by 179 · see citing works

Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy

Byrne, N. J., Rajasekaran, N. S., Abel, E. D., & Bugger, H. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.03.046 · Cited by 175 · see citing works

SGLT2 inhibition with empagliflozin improves coronary microvascular function and cardiac contractility in prediabetic ob/ob−/− mice

Adingupu, D. D., Göpel, S., Grönros, J., Behrendt, M., Soták, M., Miliotis, T., Dahlqvist, U., Gan, L., & Jönsson‐Rylander, A. (2019) · Cardiovascular Diabetology · doi:10.1186/s12933-019-0820-6 · Cited by 173 · see citing works

Molecular Dysfunction and Phenotypic Derangement in Diabetic Cardiomyopathy

Evangelista, I., Nuti, R., Picchioni, T., Dotta, F., & Palazzuoli, A. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20133264 · Cited by 170 · see citing works

Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: Role of autophagy

Guo, R., Zhang, Y., Turdi, S., & Ren, J. T. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.03.013 · Cited by 163 · see citing works

Vascular actions of insulin with implications for endothelial dysfunction

Potenza, M. A., Addabbo, F., & Montagnani, M. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00297.2009 · Cited by 162 · see citing works

The renin-angiotensin-aldosterone system (RAAS) and cardiac arrhythmias

Iravanian, S., & Dudley, S. C. (2008) · Heart Rhythm · doi:10.1016/j.hrthm.2008.02.025 · Cited by 153 · see citing works

ProteinO-GlcNAcylation: a new signaling paradigm for the cardiovascular system

Laczy, B., Hill, B. G., Wang, K., Paterson, A. J., White, C. R., Xing, D., Chen, Y.-F., Darley-Usmar, V. M., Oparil, S., & Chatham, J. C. (2008) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01056.2008 · Cited by 148 · see citing works

NADPH oxidase signaling and cardiac myocyte function

Akki, A. S., Zhang, M., Murdoch, C. E., Brewer, A. C., & Shah, A. M. (2009) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2009.04.004 · Cited by 142 · see citing works

NADPH oxidases and cardiac remodelling

Nabeebaccus, A., Zhang, M., & Shah, A. M. (2011) · Heart Failure Reviews · doi:10.1007/s10741-010-9186-2 · Cited by 138 · see citing works

Metallothionein Prevents High-Fat Diet–Induced Cardiac Contractile Dysfunction

Dong, F., Li, Q., Sreejayan, N., Nunn, J. M., & Ren, J. T. (2007) · Diabetes · doi:10.2337/db06-1596 · Cited by 136 · see citing works

Cardiac Dysfunction and Oxidative Stress in the Metabolic Syndrome: an Update on Antioxidant Therapies

Ilkun, O. L., & Boudina, S. (2013) · Current Pharmaceutical Design · doi:10.2174/1381612811319270003 · Cited by 137 · see citing works

Inhibition of NADPH oxidase reduces myocardial oxidative stress and apoptosis and improves cardiac function in heart failure after myocardial infarction

Qin, F., Simeone, M., & Patel, R. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.04.021 · Cited by 135 · see citing works

Impact of Type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart

Fülöp, N., Mason, M. M., Dutta, K., Wang, P., Davidoff, A. J., Marchase, R. B., & Chatham, J. C. (2006) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00422.2006 · Cited by 130 · see citing works

Production of Reactive Oxygen Species in the Diabetic Heart

Teshima, Y., Takahashi, N., Nishio, S., Saito, S., Kondo, H., Fukui, A., Aoki, K., Yufu, K., Nakagawa, M., & Saikawa, T. (2013) · Circulation Journal · doi:10.1253/circj.cj-13-1187 · Cited by 130 · see citing works

Common mechanisms underlying diabetic vascular complications: focus on the interaction of metabolic disorders, immuno-inflammation, and endothelial dysfunction

Xue, C., Chen, K., Gao, Z., Bao, T., Dong, L., Zhao, L., Tong, X., & Li, X. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-022-01016-w · Cited by 137 · see citing works

Oxidative stress: a key contributor to diabetic cardiomyopathyThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.

Khullar, M., Al‐Shudiefat, A. A., Lüdke, A., Binepal, G., & Singal, P. K. (2010) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y10-016 · Cited by 110 · see citing works

Angiotensin II and Oxidative Stress in the Failing Heart

Zablocki, D., & Sadoshima, J. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2012.4588 · Cited by 110 · see citing works

Chromium Alleviates Glucose Intolerance, Insulin Resistance, and Hepatic ER Stress in Obese Mice

Sreejayan, N., Dong, F., Kandadi, M. R., Yang, X., & Ren, J. T. (2008) · Obesity · doi:10.1038/oby.2008.217 · Cited by 107 · see citing works

Hypertrophic cardiomyopathy in high-fat diet-induced obesity: role of suppression of forkhead transcription factor and atrophy gene transcription

Fang, C. X., Dong, F., Thomas, D. P., Ma, H., He, L., & Ren, J. T. (2008) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00319.2008 · Cited by 104 · see citing works

Cardiac-specific overexpression of insulin-like growth factor 1 attenuates aging-associated cardiac diastolic contractile dysfunction and protein damage

Li, Q., Wu, S., Li, S., Norby, F. L., Du, ‬., Kajstura, J., Anversa, P., & Ren, J. T. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01036.2006 · Cited by 103 · see citing works

Herbal and Traditional Chinese Medicine for the Treatment of Cardiovascular Complications in Diabetes Mellitus

Ceylan‐Isik, A. F., Fliethman, R., Wold, L. E., & Ren, J. T. (2008) · Current Diabetes Reviews · doi:10.2174/157339908786241142 · Cited by 94 · see citing works

Oxidative stress in cardiomyocytes contributes to decreased SERCA2a activity in rats with metabolic syndrome

Balderas‐Villalobos, J., Molina-Muñoz, T., Mailloux‐Salinas, P., Bravo, G., Carvajal, K., & Gómez-Viquez, N. L. (2013) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00211.2013 · Cited by 92 · see citing works

Interaction between maternal and postnatal high fat diet leads to a greater risk of myocardial dysfunction in offspring via enhanced lipotoxicity, IRS-1 serine phosphorylation and mitochondrial defects

Turdi, S., Ge, W., Hu, N., Bradley, K. M., Wang, X., & Ren, J. (2013) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2012.12.007 · Cited by 88 · see citing works

Aldehyde dehydrogenase-2 (ALDH2) ameliorates chronic alcohol ingestion-induced myocardial insulin resistance and endoplasmic reticulum stress

Li, S., Gilbert, S. A. B., Li, Q., & Ren, J. T. (2009) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2009.03.017 · Cited by 86 · see citing works

Dyslipidaemia in type II diabetic mice does not aggravate contractile impairment but increases ventricular stiffness

den Bergh, A. V., Vanderper, A., Vangheluwe, P., Desjardins, F., Nevelsteen, I., Verreth, W., Wuytack, F., Holvoet, P., Flameng, W. J., Balligand, J., et al. (2007) · Cardiovascular Research · doi:10.1093/cvr/cvm001 · Cited by 82 · see citing works

Magnetic resonance imaging of progressive cardiomyopathic changes in the <i>db/db</i> mouse

Yue, P., Arai, T., Terashima, M., Sheikh, A. Y., Cao, F., Charo, D., Hoyt, G., Robbins, R. C., Ashley, E. A., Wu, J., et al. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00856.2006 · Cited by 81 · see citing works

Long-term in vivo resistin overexpression induces myocardial dysfunction and remodeling in rats

Chemaly, E. R., Hadri, L., Zhang, S., Kim, M., Kohlbrenner, E., Sheng, J., Liang, L., Chen, J., Purushothaman, K., Hajjar, R. J., et al. (2011) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2011.04.006 · Cited by 81 · see citing works

Diabetes-related cardiomyopathy: the sweet story of glucose overload from epidemiology to cellular pathways

Joubert, M., Manrique, A., Cariou, B., & Prieur, X. (2019) · Diabetes &amp; Metabolism · doi:10.1016/j.diabet.2018.07.003 · Cited by 81 · see citing works

Heart failure with preserved ejection fraction (HFpEF) in type 2 diabetes mellitus: from pathophysiology to therapeutics

Abudureyimu, M., Luo, X., Wang, X., Sowers, J. R., Wang, W., Ge, J., Ren, J. T., & Zhang, Y. (2022) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjac028 · Cited by 82 · see citing works

Nox4- and Nox2-dependent oxidant production is required for VEGF-induced SERCA cysteine-674 S-glutathiolation and endothelial cell migration

Evangelista, A. M., Thompson, M. D., Bolotina, V. M., Tong, X., & Cohen, R. A. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.10.546 · Cited by 78 · see citing works

Concurrent diabetes and heart failure: interplay and novel therapeutic approaches

Karwi, Q. G., Ho, K. L., Pherwani, S., Ketema, E. B., Sun, Q., & Lopaschuk, G. D. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab120 · Cited by 78 · see citing works

Multiple Antioxidants Improve Cardiac Complications and Inhibit Cardiac Cell Death in Streptozotocin-Induced Diabetic Rats

Kumar, S., Prasad, S., & Sitasawad, S. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067009 · Cited by 73 · see citing works

Updating Experimental Models of Diabetic Cardiomyopathy

Fuentes‐Antrás, J., Picatoste, B., Gómez‐Hernández, A., Egido, J., Tuñón, J., & Lorenzo, Ó. (2015) · Journal of Diabetes Research · doi:10.1155/2015/656795 · Cited by 72 · see citing works

Targeted GLUT-4 deficiency in the heart induces cardiomyocyte hypertrophy and impaired contractility linked with Ca2+ and proton flux dysregulation

Domenighetti, A. A., Danes, V. R., Curl, C. L., Favaloro, J. M., Proietto, J., & Delbridge, L. M. D. (2009) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2009.11.017 · Cited by 72 · see citing works

Molecular mechanism of diabetic cardiomyopathy and modulation of microRNA function by synthetic oligonucleotides

Ghosh, N., & Katare, R. (2018) · Cardiovascular Diabetology · doi:10.1186/s12933-018-0684-1 · Cited by 71 · see citing works

Cardiac overexpression of antioxidant catalase attenuates aging-induced cardiomyocyte relaxation dysfunction

Ren, J. T., Li, Q., Wu, S., Li, S., & Babcock, S. A. (2006) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2006.12.007 · Cited by 71 · see citing works

Insights into the role of maladaptive hexosamine biosynthesis and O-GlcNAcylation in development of diabetic cardiac complications

Qin, C. X., Sleaby, R., Davidoff, A. J., Bell, J. R., Blasio, M. J. D., Delbridge, L. M. D., Chatham, J. C., & Ritchie, R. H. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.12.016 · Cited by 71 · see citing works

Systemic upregulation of NADPH oxidase in diet-induced obesity in rats

Jiang, F., Lim, H. K., Morris, M. J., Prior, L. J., Velkoska, E., Wu, X. L., & Dusting, G. J. (2011) · Redox Report · doi:10.1179/174329211x13049558293713 · Cited by 68 · see citing works

Genetic loss of insulin receptors worsens cardiac efficiency in diabetes

Bugger, H., Riehle, C., Jaishy, B. P., Wende, A. R., Tuinei, J., Chen, D., Soto, J. E., Pires, K. M. P., Boudina, S., Theobald, H. A., et al. (2012) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2012.02.001 · Cited by 64 · see citing works

Chromium (D-phenylalanine)3 Supplementation Alters Glucose Disposal, Insulin Signaling, and Glucose Transporter-4 Membrane Translocation in Insulin-Resistant Mice

Dong, F., Kandadi, M. R., Ren, J. T., & Sreejayan, N. (2008) · Journal of Nutrition · doi:10.1093/jn/138.10.1846 · Cited by 63 · see citing works

Prevention of Postoperative Atrial Fibrillation: Novel and Safe Strategy Based on the Modulation of the Antioxidant System

Rodrigo, R. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00093 · Cited by 59 · see citing works

Myocardial Metabolism in Diabetic Cardiomyopathy: Potential Therapeutic Targets

Sung, M. M. Y., Hamza, S. M., & Dyck, J. R. B. (2015) · Antioxidants and Redox Signaling · doi:10.1089/ars.2015.6305 · Cited by 57 · see citing works

Energy substrate metabolism and oxidative stress in metabolic cardiomyopathy

Chen, Z., Jin, Z., Cai, J., Li, R., Deng, K., Ji, Y., Lei, F., Li, H., Lu, Z., & Li, H. (2022) · Journal of Molecular Medicine · doi:10.1007/s00109-022-02269-1 · Cited by 57 · see citing works

Cardiac-Specific Overexpression of Metallothionein Rescues against Cigarette Smoking Exposure-Induced Myocardial Contractile and Mitochondrial Damage

Hu, N., Han, X., Lane, E., Gao, F., Zhang, Y., & Ren, J. T. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057151 · Cited by 55 · see citing works

Protective effects of Hsp70 on the structure and function of SERCA2a expressed in HEK-293 cells during heat stress

Fu, M., & Tupling, A. R. (2009) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01276.2008 · Cited by 53 · see citing works

New Insights into the Immunobiology of Mononuclear Phagocytic Cells and Their Relevance to the Pathogenesis of Cardiovascular Diseases

Sanmarco, L. M., Eberhardt, N., Ponce, N. E., Cano, R. C., Bonacci, G., & Aoki, M. P. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01921 · Cited by 52 · see citing works

Cathepsin K Knockout Alleviates Pressure Overload–Induced Cardiac Hypertrophy

Hua, Y., Xu, X., Shi, G., Chicco, A. J., Ren, J. T., & Nair, S. (2013) · Hypertension · doi:10.1161/hypertensionaha.111.00947 · Cited by 47 · see citing works

Nanothermometry Measure of Muscle Efficiency

Laha, S. S., Naik, A. R., Kuhn, E. R., Alvarez, M., Sujkowski, A. L., Wessells, R. J., & Jena, B. P. (2017) · Nano Letters · doi:10.1021/acs.nanolett.6b05092 · Cited by 46 · see citing works

Role of AMP-activated protein kinase on cardio-metabolic abnormalities in the development of diabetic cardiomyopathy: A molecular landscape

Haye, A., Ansari, M. A., Rahman, S. O., Shamsi, Y., Ahmed, D., & Sharma, M. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173376 · Cited by 46 · see citing works

Long-term administration of fasudil improves cardiomyopathy in streptozotocin-induced diabetic rats

Guan, S., Ma, Z., Wu, Y., Zhang, J., Liang, F., Weiss, J. W., Guo, Q., Wang, J.-Y., Ji, E., & Chu, L. (2012) · Food and Chemical Toxicology · doi:10.1016/j.fct.2012.03.006 · Cited by 46 · see citing works

Ca2+ mishandling and cardiac dysfunction in obesity and insulin resistance: Role of oxidative stress

Carvajal, K., Balderas‐Villalobos, J., Bello-Sánchez, M. D., Phillips-Farfán, B. V., Molina-Muñoz, T., Aldana-Quintero, H. A., & Gómez-Viquez, N. L. (2014) · Cell Calcium · doi:10.1016/j.ceca.2014.08.003 · Cited by 44 · see citing works

Enhanced oxidative stress sensitizes the mitochondrial permeability transition pore to opening in heart from Zucker Fa/fa rats with type 2 diabetes

Riojas-Hernández, A., Bernal‐Ramírez, J., Rodríguez-Mier, D., Morales, E., Domínguez-Barragán, E. M., Borja-Villa, C., Rivera-Álvarez, I., García‐Rivas, G., Altamirano, J., & Garcı́a, N. (2015) · Life Sciences · doi:10.1016/j.lfs.2015.09.018 · Cited by 43 · see citing works

High‐fat Diet‐induced Obesity Leads to Resistance to Leptin‐induced Cardiomyocyte Contractile Response

Ren, J. T., Zhu, B., Relling, D. P., Esberg, L. B., & Ceylan‐Isik, A. F. (2008) · Obesity · doi:10.1038/oby.2008.381 · Cited by 43 · see citing works

Diabetes-induced changes in cardiac voltage-gated ion channels

Öztürk, N., Uslu, S., & Özdemir, S. (2021) · World Journal of Diabetes · doi:10.4239/wjd.v12.i1.1 · Cited by 42 · see citing works

Salacia oblonga root decreases cardiac hypertrophy in Zucker diabetic fatty rats: inhibition of cardiac expression of angiotensin II type 1 receptor

Huang, T. H.-W., He, L., Qin, Q., Yang, Q., Peng, G., Harada, M., Qi, Y., YAMAHARA, J., Roufogalis, B. D., & Li, Y. J. (2007) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2007.00750.x · Cited by 39 · see citing works

Chromium ( d ‐Phenylalanine)3 Improves Obesity‐Induced Cardiac Contractile Defect in ob/ob Mice

Dong, F., Yang, X., Sreejayan, N., & Ren, J. T. (2007) · Obesity · doi:10.1038/oby.2007.322 · Cited by 38 · see citing works

Activation of IGF-1 receptors and Akt signaling by systemic hyperinsulinemia contributes to cardiac hypertrophy but does not regulate cardiac autophagy in obese diabetic mice

Pires, K. M. P., Buffolo, M., Schaaf, C., Symons, J. D., Cox, J. E., Abel, E. D., Selzman, C. H., & Boudina, S. (2017) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2017.10.001 · Cited by 38 · see citing works

20years of leptin: Role of leptin in cardiomyocyte physiology and physiopathology

Feijóo‐Bandín, S., Portolés, M., Roselló‐Lletí, E., Rivera, M., González‐Juanatey, J. R., & Lago, F. (2015) · Life Sciences · doi:10.1016/j.lfs.2015.02.016 · Cited by 36 · see citing works

Electrophysiological basis of metabolic-syndrome-induced cardiac dysfunction

Okatan, E. N., Durak, A. T., & Turan, B. (2016) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2015-0531 · Cited by 36 · see citing works

Ca2+ mishandling and mitochondrial dysfunction: a converging road to prediabetic and diabetic cardiomyopathy

de Giusti, C. J., Palomeque, J., & MATTIAZZI, A. R. (2022) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-021-02650-y · Cited by 34 · see citing works

The Falconoid Luteolin Mitigates the Myocardial Inflammatory Response Induced by High-Carbohydrate/High-Fat Diet in Wistar Rats

Abu‐Elsaad, N., & El-Karef, A. (2017) · Inflammation · doi:10.1007/s10753-017-0680-8 · Cited by 32 · see citing works

Molecular mechanism of lipid-induced cardiac insulin resistance and contractile dysfunction

Liu, Y., Neumann, D., Glatz, J. F. C., & Luiken, J. J. F. P. (2016) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2016.06.002 · Cited by 31 · see citing works

Left ventricular deformation associated with cardiomyocyte Ca2+ transients delay in early stage of low-dose of STZ and high-fat diet induced type 2 diabetic rats

Liu, X., Liu, F., Deng, C., Zhang, M., Yang, M., Xiao, D., Lin, Q., Cai, S.-T., Kuang, S., Chen, J., et al. (2016) · BMC Cardiovascular Disorders · doi:10.1186/s12872-016-0220-8 · Cited by 31 · see citing works

A TSPO ligand prevents mitochondrial sterol accumulation and dysfunction during myocardial ischemia-reperfusion in hypercholesterolemic rats

Musman, J., Paradis, S., Panel, M., Pons, S., Barau, C., Caccia, C., Leoni, V., Ghaleh, B., & Morin, D. (2017) · Biochemical Pharmacology · doi:10.1016/j.bcp.2017.06.125 · Cited by 31 · see citing works

Diabetic cardiomyopathy: the need for adjusting experimental models to meet clinical reality

Lezoualc’h, F., Badimón, L., Baker, H. E., Bernard, M., Czibik, G., de Boer, R. A., d’Humières, T., Kergoat, M., Kowala, M. C., Rieusset, J., et al. (2022) · Cardiovascular Research · doi:10.1093/cvr/cvac152 · Cited by 29 · see citing works

Cardiospecific CD36 suppression by lentivirus-mediated RNA interference prevents cardiac hypertrophy and systolic dysfunction in high-fat-diet induced obese mice

Zhang, Y., Bao, M., Dai, M., Wang, X., He, W., Tan, T., Lin, D., Wang, W., Wen, Y. R., & Zhang, R. (2015) · Cardiovascular Diabetology · doi:10.1186/s12933-015-0234-z · Cited by 30 · see citing works

Regular treadmill exercise inhibits mitochondrial accumulation of cholesterol and oxysterols during myocardial ischemia-reperfusion in wild-type and ob/ob mice

Musman, J., Pons, S., Barau, C., Caccia, C., Leoni, V., Berdeaux, A., Ghaleh, B., & Morin, D. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.10.496 · Cited by 30 · see citing works

Metallothionein Alleviates Glutathione Depletion–Induced Oxidative Cardiomyopathy through CISD1-Dependent Regulation of Ferroptosis in Murine Hearts

Li, F., Fu, S., Ye, H., Hu, Y., Chen, J., Privratsky, J. R., Yu, W., Dong, F., Reiter, R. J., Dong, M., et al. (2024) · American Journal Of Pathology · doi:10.1016/j.ajpath.2024.02.009 · Cited by 27 · see citing works

SERCA2a dysfunction in the pathophysiology of heart failure with preserved ejection fraction: a direct role is yet to be established

Shooshtarian, A. K., O’Gallagher, K., Shah, A. M., & Zhang, M. (2025) · Heart Failure Reviews · doi:10.1007/s10741-025-10487-1 · Cited by 30 · see citing works

Cardiac oxidative stress in a mouse model of neutral lipid storage disease

Schrammel, A., Mußbacher, M., Winkler, S., Haemmerle, G., Stessel, H., Wölkart, G., Zechner, R., & Mayer, B. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.07.004 · Cited by 27 · see citing works

Dietary Interaction of High Fat and Marginal Copper Deficiency on Cardiac Contractile Function

Relling, D. P., Esberg, L. B., Johnson, W. T., Murphy, E. J., Carlson, E. C., Lukaski, H. C., Saari, J. T., & Ren, J. T. (2007) · Obesity · doi:10.1038/oby.2007.146 · Cited by 25 · see citing works

Inhibition of ER stress using tauroursodeoxycholic acid rescues obesity-evoked cardiac remodeling and contractile anomalies through regulation of ferroptosis

Li, F., Abudureyimu, M., Zhang, Z.-H., Tao, J., Ceylan, A. F., Lin, J., Yu, W., Reiter, R. J., Ashrafizadeh, M., Guo, J., et al. (2024) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2024.111104 · Cited by 24 · see citing works

Sex, sex steroids, and diabetic cardiomyopathy: making the case for experimental focus

Reichelt, M. E., Mellor, K. M., Bell, J. R., Chandramouli, C., Headrick, J. P., & Delbridge, L. M. D. (2013) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00141.2013 · Cited by 24 · see citing works

Platelet Functions are Decreased in Obesity and Restored after Weight Loss: Evidence for a Role of the SERCA3-Dependent ADP Secretion Pathway

Elaïb, Z., López, J., Coupaye, M., Zuber, K., Becker, Y., Kondratieff, A., Repérant, C., Pépin, M., Salomon, L., Teillet, F., et al. (2019) · Thrombosis and Haemostasis · doi:10.1055/s-0038-1677033 · Cited by 18 · see citing works

Physiological regulation of cardiac contractility by endogenous reactive oxygen species

Perjés, Á., Kubin, A., Kónyi, A., Szabados, S., Cziráki, A., Skoumal, R., Ruskoaho, H. J., & Szokodi, I. (2012) · Acta Physiologica · doi:10.1111/j.1748-1716.2012.02391.x · Cited by 23 · see citing works

Impaired cardiac contractile function in ventricular myocytes from leptin-deficient ob/ob obese mice

Dong, F., Zhang, X., Yang, X., Esberg, L. B., Yang, H., Zhang, Z., Culver, B., & Ren, J. (2006) · Journal of Endocrinology · doi:10.1677/joe.1.06241 · Cited by 155 · see citing works

Leptin Regulates Cardiomyocyte Contractile Function Through Endothelin-1 Receptor–NADPH Oxidase Pathway

Dong, F., Zhang, X., & Ren, J. T. (2005) · Hypertension · doi:10.1161/01.hyp.0000198555.51645.f1 · Cited by 123 · see citing works

Obesity is associated with increased myocardial oxidative stress

Vincent, H. K., Powers, S. K., Stewart, D., Shanely, R. A., Demirel, H. A., & Naıto, H. (1999) · International Journal of Obesity · doi:10.1038/sj.ijo.0800761 · Cited by 146 · see citing works

OBESITY IS ASSOCIATED WITH INCREASED OXIDATIVE STRESS IN THE MYOCARDIUM

Vincent, H. K., Powers, S. K., Demirel, H. A., Stewart, D. J., Naıto, H., & Shanely, R. A. (1998) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199805001-01829 · Cited by 1 · see citing works

NADPH Oxidase 2 Mediates Myocardial Oxygen Wasting in Obesity

Hafstad, A. D., Hansen, S. S., Lund, J., Santos, C. X. C., Boardman, N. T., Shah, A. M., & Aasum, E. (2020) · Antioxidants · doi:10.3390/antiox9020171 · Cited by 18 · see citing works