Jackson, Peter K.

A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis

Nachury, M. V., Loktev, A. V., Zhang, Q., Westlake, C. J., Peränen, J., Merdes, A., Slusarski, D. C., Scheller, R. H., Bazan, J. F., Sheffield, V. C., et al. (2007) · Cell

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 1,384

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Maurer, T., Garrenton, L. S., Oh, A., Pitts, K., Anderson, D. J., Skelton, N. J., Fauber, B. P., Pan, B., Malek, S., Stokoe, D., et al. (2012) · Proceedings of the National Academy of Sciences

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 618

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA

Chen, J., Jackson, P. K., Kirschner, M. W., & Dutta, A. (1995) · Nature

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 548

The Ciliary G-Protein-Coupled Receptor Gpr161 Negatively Regulates the Sonic Hedgehog Pathway via cAMP Signaling

Mukhopadhyay, S., Wen, X., Ratti, N., Loktev, A., Rangell, L., Scales, S. J., & Jackson, P. K. (2013) · Cell

Genetic and Kidney Cyst DiseasesHedgehog Signaling Pathway Studies

Cited by 486

TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia

Mukhopadhyay, S., Wen, X., Chih, B., Nelson, C. D., Lane, W. S., Scales, S. J., & Jackson, P. K. (2010) · Genes & Development

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 435

CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities

Han, K., Pierce, S. E., Li, A., Spees, K., Anderson, G. R., Seoane, J. A., Lo, Y.-H., Dubreuil, M., Olivas, M., Kamber, R. A., et al. (2020) · Nature

CRISPR and Genetic EngineeringCancer Genomics and Diagnostics

Cited by 311

Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition

Boudreau, A., Purkey, H. E., Hitz, A., Robarge, K., Peterson, D., Labadie, S., Kwong, M., Hong, R., Gao, M., Del Nagro, C., et al. (2016) · Nature Chemical Biology

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 280

The primary cilium as a cellular receiver: organizing ciliary GPCR signaling

Hilgendorf, K. I., Johnson, C. T., & Jackson, P. K. (2016) · Current Opinion in Cell Biology

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 224

Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia

Loktev, A. V., & Jackson, P. K. (2013) · Cell Reports

Genetic and Kidney Cyst DiseasesRegulation of Appetite and Obesity

Cited by 212

Smoothened determines β-arrestin–mediated removal of the G protein–coupled receptor Gpr161 from the primary cilium

Pal, K., Hwang, S.-H., Somatilaka, B., Badgandi, H., Jackson, P. K., DeFea, K., & Mukhopadhyay, S. (2016) · Journal of Cell Biology

Genetic and Kidney Cyst DiseasesReceptor Mechanisms and Signaling

Cited by 141

The STARD9/Kif16a Kinesin Associates with Mitotic Microtubules and Regulates Spindle Pole Assembly

Torres, J. Z., Summers, M. K., Peterson, D., Brauer, M. J., Lee, J., Senese, S., Gholkar, A. A., Lo, Y.-C., Lei, X., Jung, K., et al. (2011) · Cell

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 80

Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A

Wu, J. Q., Hansen, D. V., Guo, Y., Wang, M. Z., Tang, W., Freel, C. D., Tung, J. J., Jackson, P. K., & Kornbluth, S. (2007) · Proceedings of the National Academy of Sciences

Microtubule and mitosis dynamicsCancer-related Molecular Pathways

Cited by 56

A hierarchical pathway for assembly of the distal appendages that organize primary cilia

Kanie, T., Love, J. F., Fisher, S. D., Gustavsson, A.-K., & Jackson, P. K. (2023) · eLife

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 32

LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer

Murray, C. W., Brady, J. J., Han, M., Cai, H., Tsai, M. K., Pierce, S. E., Cheng, R., Demeter, J., Feldser, D. M., Jackson, P. K., et al. (2022) · Nature Communications

Lung Cancer Research StudiesLung Cancer Treatments and Mutations

Cited by 22

A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3

Lahtela, J., Corson, L. B., Hemmes, A., Brauer, M. J., Koopal, S., Lee, J., Hunsaker, T. L., Jackson, P. K., & Verschuren, E. W. (2013) · Cell Cycle

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 20

TTBK2 kinase: linking primary cilia and cerebellar ataxias

Jackson, P. K. (2012) · Cell

Genetic and Kidney Cyst DiseasesGenetic Neurodegenerative Diseases

Cited by 17

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2

Karim, M., Mishra, M., Lo, C.-W., Saul, S., Cagirici, H. B., Gourdelier, M., Ghita, L., Ojha, A., Tran, D. H. N., Agrawal, A., et al. (2025) · Nature Communications

SARS-CoV-2 and COVID-19 ResearchAutophagy in Disease and Therapy

Cited by 16

Myristoylated Neuronal Calcium Sensor-1 captures the preciliary vesicle at distal appendages

Kanie, T., Ng, R., Abbott, K. L., Tanvir, N. M., Lorentzen, E., Pongs, O., & Jackson, P. K. (2025) · eLife

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 5